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Pathophysiological Role and Medicinal Chemistry of A2A Adenosine Receptor Antagonists in Alzheimer’s Disease

Molecules (Basel, Switzerland), 2022-04, Vol.27 (9), p.2680

2022

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Ligand design by targeting a binding site water

Chemical science (Cambridge), 2020-11, Vol.12 (3), p.96-968

2020

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Exploring allene chemistry using phosphorus-based allenes as scaffolds

Pure and applied chemistry, 2017-03, Vol.89 (3), p.367-377

2017

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Pharmacological characterization of DPTN and other selective A3 adenosine receptor antagonists

Purinergic signalling, 2021-12, Vol.17 (4), p.737-746

2021

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Expanding the repertoire of methanocarba nucleosides from purinergic signaling to diverse targets

RSC medicinal chemistry, 2021-11, Vol.12 (11), p.188-1825

2021

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Design and in vivo activity of A3 adenosine receptor agonist prodrugs

Purinergic signalling, 2020-09, Vol.16 (3), p.367-377

2020

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Fluorescent A2A and A3 adenosine receptor antagonists as flow cytometry probes

Purinergic signalling, 2023-09, Vol.19 (3), p.565-578

2023

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Convergent synthesis of 2-thioether-substituted ()-methanocarba-adenosines as purine receptor agonists

RSC advances, 2021-08, Vol.11 (44), p.27369-2738

2021

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Nucleotide P2Y1 receptor agonists are in vitro and in vivo prodrugs of A1/A3 adenosine receptor agonists: implications for roles of P2Y1 and A1/A3 receptors in physiology and pathology

Purinergic signalling, 2020-12, Vol.16 (4), p.543-559

2020

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Activation of adenosine A2A or A2B receptors causes hypothermia in mice

Neuropharmacology, 2018-09, Vol.139, p.268-278

2018

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Allosteric Antagonism of the A2A Adenosine Receptor by a Series of Bitopic Ligands

Cells (Basel, Switzerland), 2020-05, Vol.9 (5), p.1200

2020

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Lipid Trolling to Optimize A3 Adenosine Receptor-Positive Allosteric Modulators (PAMs)

Journal of medicinal chemistry, 2024-07, Vol.67 (14), p.12221-12247

2024

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Palladium-Catalyzed Annulation of Allenes with Indole-2-carboxylic Acid Derivatives: Synthesis of Indolo[2,3‑c]pyrane-1-ones via Ar–I Reactivity or C–H Functionalization

Journal of organic chemistry, 2012-08, Vol.77 (16), p.6959-6969

2012

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Lipid Trolling to Optimize A 3 Adenosine Receptor-Positive Allosteric Modulators (PAMs)

Journal of medicinal chemistry, 2024-07, Vol.67 (14), p.12221-12247

2024

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Structure–Activity Studies of 1H‑Imidazo[4,5‑c]quinolin-4-amine Derivatives as A3 Adenosine Receptor Positive Allosteric Modulators

Journal of medicinal chemistry, 2022-11, Vol.65 (22), p.15238-15262

2022

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Structure-Activity Studies of 1 H -Imidazo[4,5- c ]quinolin-4-amine Derivatives as A 3 Adenosine Receptor Positive Allosteric Modulators

Journal of medicinal chemistry, 2022-11, Vol.65 (22), p.15238-15262

2022

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Activation of adenosine A 2A or A 2B receptors causes hypothermia in mice

Neuropharmacology, 2018-09, Vol.139, p.268

2018

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Molecularly Nonstoichiometric Crystals in Phosphorus Compounds

Inorganic chemistry, 2007-11, Vol.46 (23), p.9819-9826

2007

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A2A adenosine receptor agonists, antagonists, inverse agonists and partial agonists

International review of neurobiology, 2023, Vol.170, p.1-27

2023

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2-Amino-5-arylethynyl-thiophen-3-yl-(phenyl)methanones as A 1 Adenosine Receptor Positive Allosteric Modulators

ACS medicinal chemistry letters, 2023-12, Vol.14 (12), p.1640-1646

2023

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Assay-Dependent Inverse Agonism at the A3 Adenosine Receptor: When Neutral Is Not Neutral

ACS pharmacology & translational science, 2023-09, Vol.6 (9), p.1266-1274

2023

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Assay-Dependent Inverse Agonism at the A 3 Adenosine Receptor: When Neutral Is Not Neutral

ACS pharmacology & translational science, 2023-09, Vol.6 (9), p.1266-1274

2023

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2‑Amino-5-arylethynyl-thiophen-3-yl-(phenyl)methanones as A1 Adenosine Receptor Positive Allosteric Modulators

ACS medicinal chemistry letters, 2023-12, Vol.14 (12), p.1640-1646

2023

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Selective A3 Adenosine Receptor Antagonist Radioligand for Human and Rodent Species

ACS medicinal chemistry letters, 2022-04, Vol.13 (4), p.623-631

2022

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Selective A 3 Adenosine Receptor Antagonist Radioligand for Human and Rodent Species

ACS medicinal chemistry letters, 2022-04, Vol.13 (4), p.623-631

2022

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Pathophysiological Role and Medicinal Chemistry of A2A Adenosine Receptor Antagonists in Alzheimer’s Disease

Ligand design by targeting a binding site water

Exploring allene chemistry using phosphorus-based allenes as scaffolds

Pharmacological characterization of DPTN and other selective A3 adenosine receptor antagonists

Expanding the repertoire of methanocarba nucleosides from purinergic signaling to diverse targets

Design and in vivo activity of A3 adenosine receptor agonist prodrugs

Fluorescent A2A and A3 adenosine receptor antagonists as flow cytometry probes

Convergent synthesis of 2-thioether-substituted ()-methanocarba-adenosines as purine receptor agonists

Nucleotide P2Y1 receptor agonists are in vitro and in vivo prodrugs of A1/A3 adenosine receptor agonists: implications for roles of P2Y1 and A1/A3 receptors in physiology and pathology

Activation of adenosine A2A or A2B receptors causes hypothermia in mice

Allosteric Antagonism of the A2A Adenosine Receptor by a Series of Bitopic Ligands

Lipid Trolling to Optimize A3 Adenosine Receptor-Positive Allosteric Modulators (PAMs)

Palladium-Catalyzed Annulation of Allenes with Indole-2-carboxylic Acid Derivatives: Synthesis of Indolo[2,3‑c]pyrane-1-ones via Ar–I Reactivity or C–H Functionalization

Lipid Trolling to Optimize A 3 Adenosine Receptor-Positive Allosteric Modulators (PAMs)

Structure–Activity Studies of 1H‑Imidazo[4,5‑c]quinolin-4-amine Derivatives as A3 Adenosine Receptor Positive Allosteric Modulators

Structure-Activity Studies of 1 H -Imidazo[4,5- c ]quinolin-4-amine Derivatives as A 3 Adenosine Receptor Positive Allosteric Modulators

Activation of adenosine A 2A or A 2B receptors causes hypothermia in mice

Molecularly Nonstoichiometric Crystals in Phosphorus Compounds

A2A adenosine receptor agonists, antagonists, inverse agonists and partial agonists

2-Amino-5-arylethynyl-thiophen-3-yl-(phenyl)methanones as A 1 Adenosine Receptor Positive Allosteric Modulators

Assay-Dependent Inverse Agonism at the A3 Adenosine Receptor: When Neutral Is Not Neutral

Assay-Dependent Inverse Agonism at the A 3 Adenosine Receptor: When Neutral Is Not Neutral

2‑Amino-5-arylethynyl-thiophen-3-yl-(phenyl)methanones as A1 Adenosine Receptor Positive Allosteric Modulators

Selective A3 Adenosine Receptor Antagonist Radioligand for Human and Rodent Species

Selective A 3 Adenosine Receptor Antagonist Radioligand for Human and Rodent Species

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