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Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model

eLife, 2020-01, Vol.9

2020

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Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection

Gut microbes, 2020-11, Vol.12 (1), p.1752125-1752125

2020

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Pleiotropic ZIP8 A391T implicates abnormal manganese homeostasis in complex human disease

JCI insight, 2020-10, Vol.5 (20)

2020

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Tu1432: MANGANESE HOMEOSTASIS IS PERTURBED IN THE SETTING OF INTESTINAL INFLAMMATION

Gastroenterology (New York, N.Y. 1943), 2022-05, Vol.162 (7), p.S-958

2022

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Hepatobiliary manganese homeostasis is dynamic in the setting of inflammation or infection in mice

The FASEB journal, 2023-09, Vol.37 (9), p.e23123-n/a

2023

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Fr147 CROHN'S DISEASE-ASSOCIATED GENETIC VARIATION IN METAL TRANSPORTER ZIP8 (A391T) REDUCES STABILITY OF PLASMA MEMBRANE ZIP8 IN HEK293 CELLS

Gastroenterology (New York, N.Y. 1943), 2021-05, Vol.160 (6), p.S-238-S-238

2021

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The zinc sensing receptor, ZnR/GPR39, in health and disease

Frontiers in bioscience, 2017-03, Vol.22 (9), p.1469-1492, Article 4554

2017

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The zinc sensing receptor, ZnR/GPR39, triggers metabotropic calcium signalling in colonocytes and regulates occludin recovery in experimental colitis

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2016-08, Vol.371 (1700), p.20150420

2016

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The Zn2+-sensing receptor, ZnR/GPR39, upregulates colonocytic Cl− absorption, via basolateral KCC1, and reduces fluid loss

Biochimica et biophysica acta. Molecular basis of disease, 2017-04, Vol.1863 (4), p.947-960

2017

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Mechanical Stimuli Affect Escherichia coli Heat-Stable Enterotoxin-Cyclic GMP Signaling in a Human Enteroid Intestine-Chip Model

Infection and immunity, 2020-02, Vol.88 (3)

2020

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Mo1794 CROHN'S DISEASE-ASSOCIATED PATHOGENIC MUTATION IN MANGANESE TRANSPORTER ZIP8 SHIFTS THE ILEAL AND RECTAL MUCOSAL MICROBIOTA IMPLICATING ABERRANT BILE ACID METABOLISM

Gastroenterology (New York, N.Y. 1943), 2024-05, Vol.166 (5), p.S-1114-S-1114

2024

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Fluid shear stress enhances differentiation of jejunal human enteroids in Intestine-Chip

American journal of physiology: Gastrointestinal and liver physiology, 2021-03, Vol.320 (3), p.G258-G271

2021

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Crohn’s Disease–Associated Pathogenic Mutation in the Manganese Transporter ZIP8 Shifts the Ileal and Rectal Mucosal Microbiota Implicating Aberrant Bile Acid Metabolism

Inflammatory bowel diseases, 2024-08, Vol.30 (8), p.1379-1388

2024

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Su1012 – Mechanical Stimuli Affect Enterotoxigenic E. Coli (ETEC) Heat Stable Enterotoxin (ST)-Cyclic Nucleotide Signaling by Altering Mrp4 Expression in a Human Enteroid Monolayer Model of Etec Diarrhea

Gastroenterology (New York, N.Y. 1943), 2019-05, Vol.156 (6), p.S-485-S-485

2019

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Correction to ‘The zinc sensing receptor, ZnR/GPR39, triggers metabotropic calcium signalling in colonocytes and regulates occludin recovery in experimental colitis’

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2016-09, Vol.371 (1703), p.20160331

2016

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The Zn 2+ -sensing receptor, ZnR/GPR39, upregulates colonocytic Cl - absorption, via basolateral KCC1, and reduces fluid loss

Biochimica et biophysica acta. Molecular basis of disease, 2017-04, Vol.1863 (4), p.947-960

2017

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197 - Enterotoxigenic E. Coli (ETEC) Pathogenesis Modeled in Human Enteroid Monolayers Demonstrates MRP-Related Cyclic Nucleotide Secretion

Gastroenterology (New York, N.Y. 1943), 2017-04, Vol.152 (5), p.S57-S57

2017

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Enterotoxigenic E. Coli (ETEC) Pathogenesis Modeled in Human Enteroid Monolayers Demonstrates MRP-Related Cyclic Nucleotide Secretion

Gastroenterology (New York, N.Y. 1943), 2017-04, Vol.152 (5), p.S57-S57

2017

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269 - A Novel Model of Human Enteroids in the Intestine-Chip (I-C) Platform that Includes Dynamic Flow and Cyclic Strain for Physiological and Phamacological Studies of Intestinal Ion Transport

Gastroenterology (New York, N.Y. 1943), 2018-05, Vol.154 (6), p.S-66-S-66

2018

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Prevalence of Metabolic Syndrome in Local Population of Patan

Medical journal of Shree Birendra Hospital, 2013-03, Vol.11 (1), p.27-31

2013

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Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model

Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection

Pleiotropic ZIP8 A391T implicates abnormal manganese homeostasis in complex human disease

Tu1432: MANGANESE HOMEOSTASIS IS PERTURBED IN THE SETTING OF INTESTINAL INFLAMMATION

Hepatobiliary manganese homeostasis is dynamic in the setting of inflammation or infection in mice

Fr147 CROHN'S DISEASE-ASSOCIATED GENETIC VARIATION IN METAL TRANSPORTER ZIP8 (A391T) REDUCES STABILITY OF PLASMA MEMBRANE ZIP8 IN HEK293 CELLS

The zinc sensing receptor, ZnR/GPR39, in health and disease

The zinc sensing receptor, ZnR/GPR39, triggers metabotropic calcium signalling in colonocytes and regulates occludin recovery in experimental colitis

The Zn2+-sensing receptor, ZnR/GPR39, upregulates colonocytic Cl− absorption, via basolateral KCC1, and reduces fluid loss

Mechanical Stimuli Affect Escherichia coli Heat-Stable Enterotoxin-Cyclic GMP Signaling in a Human Enteroid Intestine-Chip Model

Mo1794 CROHN'S DISEASE-ASSOCIATED PATHOGENIC MUTATION IN MANGANESE TRANSPORTER ZIP8 SHIFTS THE ILEAL AND RECTAL MUCOSAL MICROBIOTA IMPLICATING ABERRANT BILE ACID METABOLISM

Fluid shear stress enhances differentiation of jejunal human enteroids in Intestine-Chip

Crohn’s Disease–Associated Pathogenic Mutation in the Manganese Transporter ZIP8 Shifts the Ileal and Rectal Mucosal Microbiota Implicating Aberrant Bile Acid Metabolism

Su1012 – Mechanical Stimuli Affect Enterotoxigenic E. Coli (ETEC) Heat Stable Enterotoxin (ST)-Cyclic Nucleotide Signaling by Altering Mrp4 Expression in a Human Enteroid Monolayer Model of Etec Diarrhea

Correction to ‘The zinc sensing receptor, ZnR/GPR39, triggers metabotropic calcium signalling in colonocytes and regulates occludin recovery in experimental colitis’

The Zn 2+ -sensing receptor, ZnR/GPR39, upregulates colonocytic Cl - absorption, via basolateral KCC1, and reduces fluid loss

197 - Enterotoxigenic E. Coli (ETEC) Pathogenesis Modeled in Human Enteroid Monolayers Demonstrates MRP-Related Cyclic Nucleotide Secretion

Enterotoxigenic E. Coli (ETEC) Pathogenesis Modeled in Human Enteroid Monolayers Demonstrates MRP-Related Cyclic Nucleotide Secretion

269 - A Novel Model of Human Enteroids in the Intestine-Chip (I-C) Platform that Includes Dynamic Flow and Cyclic Strain for Physiological and Phamacological Studies of Intestinal Ion Transport

Prevalence of Metabolic Syndrome in Local Population of Patan

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