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Roles of eukaryotic topoisomerases in transcription, replication and genomic stability

Nature reviews. Molecular cell biology, 2016-11, Vol.17 (11), p.703-721

2016

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Excision repair of topoisomerase DNA-protein crosslinks (TOP-DPC)

DNA repair, 2020-05, Vol.89, p.102837-102837, Article 102837

2020

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Cardiac Events After Radiation Therapy: Combined Analysis of Prospective Multicenter Trials for Locally Advanced Non-Small-Cell Lung Cancer

Journal of clinical oncology, 2017-05, Vol.35 (13), p.1395-1402

2017

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Design of topology optimized compliant legs for bio-inspired quadruped robots

Scientific reports, 2023-03, Vol.13 (1), p.4875-4875, Article 4875

2023

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The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin

Nature cell biology, 2022-01, Vol.24 (1), p.62-73

2022

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PARP1-driven repair of topoisomerase IIIα DNA-protein crosslinks by FEN1

Cell reports (Cambridge), 2024-08, Vol.43 (8), p.114522, Article 114522

2024

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Radiation-Induced Insufficiency Fractures After Pelvic Irradiation for Gynecologic Malignancies: A Systematic Review

International journal of radiation oncology, biology, physics, 2020-11, Vol.108 (3), p.620-634

2020

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Levofloxacin Prophylaxis During Induction Therapy for Pediatric Acute Lymphoblastic Leukemia

Clinical infectious diseases, 2017-12, Vol.65 (11), p.1790-1798

2017

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Early HPV ctDNA Kinetics and Imaging Biomarkers Predict Therapeutic Response in p16+ Oropharyngeal Squamous Cell Carcinoma

Clinical cancer research, 2022-01, Vol.28 (2), p.350-359

2022

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PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylation

Nature communications, 2021-08, Vol.12 (1), p.5010-5010, Article 5010

2021

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Replication-associated formation and repair of human topoisomerase IIIα cleavage complexes

Nature communications, 2023-04, Vol.14 (1), p.1925-1925, Article 1925

2023

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Age, race, insurance type, and digital divide index are associated with video visit completion for patients seen for oncologic care in a large hospital system during the COVID-19 pandemic

PloS one, 2022-11, Vol.17 (11), p.e0277617-e0277617

2022

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The TDRD3-USP9X complex and MIB1 regulate TOP3B homeostasis and prevent deleterious TOP3B cleavage complexes

Nature communications, 2023-11, Vol.14 (1), p.7524-7524, Article 7524

2023

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PD-L1 induction via the MEK-JNK-AP1 axis by a neddylation inhibitor promotes cancer-associated immunosuppression

Cell death & disease, 2022-10, Vol.13 (10), p.844-844, Article 844

2022

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Design of a spider-inspired wheeled compliant leg for search mobile robots

Biomimetic intelligence and robotics, 2024-12, Vol.4 (4), p.100182, Article 100182

2024

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Quantitative Detection of DNA-Protein Crosslinks and Their Post-Translational Modifications

Journal of visualized experiments, 2023-04 (194)

Sun, Yilun

2023

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Targeting neddylation sensitizes colorectal cancer to topoisomerase I inhibitors by inactivating the DCAF13-CRL4 ubiquitin ligase complex

Nature communications, 2023-06, Vol.14 (1), p.3762-20, Article 3762

2023

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SUMO: A Swiss Army Knife for Eukaryotic Topoisomerases

Frontiers in molecular biosciences, 2022-04, Vol.9, p.871161-871161

2022

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Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity

eLife, 2020-02, Vol.9

2020

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Low Retinol-Binding Protein and Vitamin D Levels Are Associated with Severe Outcomes in Children Hospitalized with Lower Respiratory Tract Infection and Respiratory Syncytial Virus or Human Metapneumovirus Detection

The Journal of pediatrics, 2017-08, Vol.187, p.323-327

2017

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Stochastic Tree Search for Estimating Optimal Dynamic Treatment Regimes

Journal of the American Statistical Association, 2021-03, Vol.116 (533), p.421-432

2021

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Autophagy-Dependent Sensitization of Triple-Negative Breast Cancer Models to Topoisomerase II Poisons by Inhibition of the Nucleosome Remodeling Factor

Molecular cancer research, 2021-08, Vol.19 (8), p.1338-1349

2021

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Sensing and signaling of immunogenic extracellular RNAs restrain group 2 innate lymphoid cell-driven acute lung inflammation and airway hyperresponsiveness

PloS one, 2020-07, Vol.15 (7), p.e0236744

2020

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Immune Sensing of Aeroallergen-Associated Double-Stranded RNA Triggers an IFN Response and Modulates Type 2 Lung Inflammation

The Journal of immunology (1950), 2019-11, Vol.203 (9), p.2520-2531

2019

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Prediction of attributable mortality in pediatric patients with cancer admitted to the intensive care unit for suspected infection: A comprehensive evaluation of risk scores

Cancer medicine (Malden, MA), 2023-12, Vol.12 (23), p.21287-21292

2023

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Roles of eukaryotic topoisomerases in transcription, replication and genomic stability

Excision repair of topoisomerase DNA-protein crosslinks (TOP-DPC)

Cardiac Events After Radiation Therapy: Combined Analysis of Prospective Multicenter Trials for Locally Advanced Non-Small-Cell Lung Cancer

Design of topology optimized compliant legs for bio-inspired quadruped robots

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin

PARP1-driven repair of topoisomerase IIIα DNA-protein crosslinks by FEN1

Radiation-Induced Insufficiency Fractures After Pelvic Irradiation for Gynecologic Malignancies: A Systematic Review

Levofloxacin Prophylaxis During Induction Therapy for Pediatric Acute Lymphoblastic Leukemia

Early HPV ctDNA Kinetics and Imaging Biomarkers Predict Therapeutic Response in p16+ Oropharyngeal Squamous Cell Carcinoma

PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylation

Replication-associated formation and repair of human topoisomerase IIIα cleavage complexes

Age, race, insurance type, and digital divide index are associated with video visit completion for patients seen for oncologic care in a large hospital system during the COVID-19 pandemic

The TDRD3-USP9X complex and MIB1 regulate TOP3B homeostasis and prevent deleterious TOP3B cleavage complexes

PD-L1 induction via the MEK-JNK-AP1 axis by a neddylation inhibitor promotes cancer-associated immunosuppression

Design of a spider-inspired wheeled compliant leg for search mobile robots

Quantitative Detection of DNA-Protein Crosslinks and Their Post-Translational Modifications

Targeting neddylation sensitizes colorectal cancer to topoisomerase I inhibitors by inactivating the DCAF13-CRL4 ubiquitin ligase complex

SUMO: A Swiss Army Knife for Eukaryotic Topoisomerases

Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity

Low Retinol-Binding Protein and Vitamin D Levels Are Associated with Severe Outcomes in Children Hospitalized with Lower Respiratory Tract Infection and Respiratory Syncytial Virus or Human Metapneumovirus Detection

Stochastic Tree Search for Estimating Optimal Dynamic Treatment Regimes

Autophagy-Dependent Sensitization of Triple-Negative Breast Cancer Models to Topoisomerase II Poisons by Inhibition of the Nucleosome Remodeling Factor

Sensing and signaling of immunogenic extracellular RNAs restrain group 2 innate lymphoid cell-driven acute lung inflammation and airway hyperresponsiveness

Immune Sensing of Aeroallergen-Associated Double-Stranded RNA Triggers an IFN Response and Modulates Type 2 Lung Inflammation

Prediction of attributable mortality in pediatric patients with cancer admitted to the intensive care unit for suspected infection: A comprehensive evaluation of risk scores

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