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NBI-921352, a first-in-class, NaV1.6 selective, sodium channel inhibitor that prevents seizures in Scn8a gain-of-function mice, and wild-type mice and rats

eLife, 2022-03, Vol.11

2022

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Applications of amide isosteres in medicinal chemistry

Bioorganic & medicinal chemistry letters, 2019-09, Vol.29 (18), p.2535-2550

2019

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Methyl-containing pharmaceuticals: Methylation in drug design

Bioorganic & medicinal chemistry letters, 2018-11, Vol.28 (20), p.3283-3289

2018

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Investigation on machinability of SiCp/Al composites under the synergistic effect of pulsed laser assisted and ultrasonic elliptical vibration cutting

Journal of materials processing technology, 2024-11, Vol.332, p.118561, Article 118561

2024

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Biologically active metabolites in drug discovery

Bioorganic & medicinal chemistry letters, 2021-09, Vol.48, p.128255-128255, Article 128255

2021

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Optimization of MRP quartz glass process parameters based on BP-PSO

Materials and manufacturing processes, 2024-09, Vol.39 (12), p.1689-1698

2024

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Chinese-language film or Chinese cinema? Review of an ongoing debate in the Chinese mainland

Journal of Chinese cinemas, 2016-01, Vol.10 (1), p.61-66

Sun, Shaoyi

2016

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Identification of key enzymes involved in the accumulation of carotenoids during fruit ripening of Lycium barbarum L. by a proteomic approach

International journal of food science & technology, 2021-10, Vol.56 (10), p.5050-5061

2021

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The contribution of Na V 1.6 to the efficacy of voltage-gated sodium channel inhibitors in wild type and Na V 1.6 gain-of-function (GOF) mouse seizure control

British journal of pharmacology, 2024-10, Vol.181 (20), p.3993-4011

2024

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The contribution of NaV1.6 to the efficacy of voltage‐gated sodium channel inhibitors in wild type and NaV1.6 gain‐of‐function (GOF) mouse seizure control

British journal of pharmacology, 2024-10, Vol.181 (20), p.3993-4011

2024

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The discovery of benzenesulfonamide-based potent and selective inhibitors of voltage-gated sodium channel Nav1.7

Bioorganic & medicinal chemistry letters, 2014-09, Vol.24 (18), p.4397-4401

2014

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Identification of aryl sulfonamides as novel and potent inhibitors of NaV1.5

Bioorganic & medicinal chemistry letters, 2021-08, Vol.45, p.128133-128133, Article 128133

2021

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The discovery of glycine and related amino acid-based factor Xa inhibitors

Bioorganic & medicinal chemistry, 2006-07, Vol.14 (13), p.4379-4392

2006

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Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNa V 1.7 Inhibitors for the Treatment of Pain

Journal of medicinal chemistry, 2018-06, Vol.61 (11), p.4810

2018

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Discovery of Acyl-sulfonamide Nav1.7 Inhibitors GDC-0276 and GDC-0310

Journal of medicinal chemistry, 2021-03, Vol.64 (6), p.2953-2966

2021

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The discovery of benzenesulfonamide-based potent and selective inhibitors of voltage-gated sodium channel Na(v)1.7

Bioorganic & medicinal chemistry letters, 2014-09, Vol.24 (18), p.4397

2014

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Discovery of Acyl-sulfonamide Na v 1.7 Inhibitors GDC-0276 and GDC-0310

Journal of medicinal chemistry, 2021-03, Vol.64 (6), p.2953-2966

2021

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Carbon Neutrality Goal Is Too Far Away? Residents’ Psychological Distance of Low-Carbon Policy Over Time and Space in China

Green and Low-Carbon Economy, 2023-04

2023

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Inhibitors of voltage-gated Sodium Channel Na v 1.7: Patent Applications Since 2010

Pharmaceutical patent analyst, 2014-09, Vol.3 (5), p.509-521

2014

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Discovery of Piperazin-1-ylpyridazine-Based Potent and Selective Stearoyl-CoA Desaturase‑1 Inhibitors for the Treatment of Obesity and Metabolic Syndrome

Journal of medicinal chemistry, 2013-01, Vol.56 (2), p.568-583

2013

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Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N -([1,2,4]Triazolo[4,3- a ]pyridin-3-yl)methane-sulfonamides as Potent and Selective h Na V 1.7 Inhibitors for the Treatment of Pain

Journal of medicinal chemistry, 2018-06, Vol.61 (11), p.4810-4831

2018

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Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N‑([1,2,4]Triazolo[4,3‑a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNaV1.7 Inhibitors for the Treatment of Pain

Journal of medicinal chemistry, 2018-06, Vol.61 (11), p.4810-4831

2018

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Discovery of triazolone derivatives as novel, potent stearoyl-CoA desaturase-1 (SCD1) inhibitors

Bioorganic & medicinal chemistry, 2015-02, Vol.23 (3), p.455-465

2015

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Inhibitors of voltage-gated sodium channel Nav1.7: patent applications since 2010

Pharmaceutical patent analyst, 2014-09, Vol.3 (5), p.509-521

2014

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NBI-921352, a first-in-class, NaV1.6 selective, sodium channel inhibitor that prevents seizures in Scn8a gain-of-function mice, and wild-type mice and rats

Applications of amide isosteres in medicinal chemistry

Methyl-containing pharmaceuticals: Methylation in drug design

Investigation on machinability of SiCp/Al composites under the synergistic effect of pulsed laser assisted and ultrasonic elliptical vibration cutting

Biologically active metabolites in drug discovery

Optimization of MRP quartz glass process parameters based on BP-PSO

Chinese-language film or Chinese cinema? Review of an ongoing debate in the Chinese mainland

Identification of key enzymes involved in the accumulation of carotenoids during fruit ripening of Lycium barbarum L. by a proteomic approach

The contribution of Na V 1.6 to the efficacy of voltage-gated sodium channel inhibitors in wild type and Na V 1.6 gain-of-function (GOF) mouse seizure control

The contribution of NaV1.6 to the efficacy of voltage‐gated sodium channel inhibitors in wild type and NaV1.6 gain‐of‐function (GOF) mouse seizure control

The discovery of benzenesulfonamide-based potent and selective inhibitors of voltage-gated sodium channel Nav1.7

Identification of Selective Acyl Sulfonamide–Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (NaV) 1.7 with Potent Analgesic Activity

Identification of aryl sulfonamides as novel and potent inhibitors of NaV1.5

The discovery of glycine and related amino acid-based factor Xa inhibitors

Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNa V 1.7 Inhibitors for the Treatment of Pain

Discovery of Acyl-sulfonamide Nav1.7 Inhibitors GDC-0276 and GDC-0310

The discovery of benzenesulfonamide-based potent and selective inhibitors of voltage-gated sodium channel Na(v)1.7

Discovery of Acyl-sulfonamide Na v 1.7 Inhibitors GDC-0276 and GDC-0310

Carbon Neutrality Goal Is Too Far Away? Residents’ Psychological Distance of Low-Carbon Policy Over Time and Space in China

Inhibitors of voltage-gated Sodium Channel Na v 1.7: Patent Applications Since 2010

Discovery of Piperazin-1-ylpyridazine-Based Potent and Selective Stearoyl-CoA Desaturase‑1 Inhibitors for the Treatment of Obesity and Metabolic Syndrome

Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N -([1,2,4]Triazolo[4,3- a ]pyridin-3-yl)methane-sulfonamides as Potent and Selective h Na V 1.7 Inhibitors for the Treatment of Pain

Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N‑([1,2,4]Triazolo[4,3‑a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNaV1.7 Inhibitors for the Treatment of Pain

Discovery of triazolone derivatives as novel, potent stearoyl-CoA desaturase-1 (SCD1) inhibitors

Inhibitors of voltage-gated sodium channel Nav1.7: patent applications since 2010

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