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Olaparib hydroxamic acid derivatives as dual PARP and HDAC inhibitors for cancer therapy

Bioorganic & medicinal chemistry, 2017-08, Vol.25 (15), p.4100-4109

2017

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Antitumor Activity of s-Triazine Derivatives: A Systematic Review

Molecules (Basel, Switzerland), 2023-05, Vol.28 (11), p.4278

2023

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Branched rolling circle amplification method for measuring serum circulating microRNA levels for early breast cancer detection

Cancer science, 2018-09, Vol.109 (9), p.2897-2906

2018

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Combined inhibition of HDAC and DNMT1 induces p85α/MEK-mediated cell cycle arrest by dual target inhibitor 208 in U937 cells

Chinese chemical letters, 2019-06, Vol.30 (6), p.1233-1236

2019

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Design, synthesis and antitumor evaluations of nucleoside base hydroxamic acid derivatives as DNMT and HDAC dual inhibitors

Chinese chemical letters, 2021-08, Vol.32 (8), p.2479-2483

2021

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TRIP13, identified as a hub gene of tumor progression, is the target of microRNA-4693-5p and a potential therapeutic target for colorectal cancer

Cell death discovery, 2022-01, Vol.8 (1), p.35-35, Article 35

2022

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Design, synthesis and biological evaluation of novel phthalazinone acridine derivatives as dual PARP and Topo inhibitors for potential anticancer agents

Chinese chemical letters, 2020-02, Vol.31 (2), p.404-408

2020

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IBSP, a potential recurrence biomarker, promotes the progression of colorectal cancer via Fyn/β‐catenin signaling pathway

Cancer medicine (Malden, MA), 2021-06, Vol.10 (12), p.4030-4045

2021

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Exploration of acridine scaffold as a potentially interesting scaffold for discovering novel multi-target VEGFR-2 and Src kinase inhibitors

Bioorganic & medicinal chemistry, 2011-06, Vol.19 (11), p.3312-3319

2011

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Discovery of novel nucleoside derivatives as selective lysine acetyltransferase p300 inhibitors for cancer therapy

Bioorganic & medicinal chemistry letters, 2024-05, Vol.104, p.129742-129742, Article 129742

2024

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Current discovery strategies for hepatocellular carcinoma therapeutics

Expert opinion on drug discovery, 2020-02, Vol.15 (2), p.243-258

2020

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Design, synthesis and anticancer potential of NSC-319745 hydroxamic acid derivatives as DNMT and HDAC inhibitors

European journal of medicinal chemistry, 2017-07, Vol.134, p.281-292

2017

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Synthesis and biological evaluation of benzimidazole acridine derivatives as potential DNA-binding and apoptosis-inducing agents

Bioorganic & medicinal chemistry, 2015-04, Vol.23 (8), p.1800-1807

2015

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Quinazoline-based hydroxamic acid derivatives as dual histone methylation and deacetylation inhibitors for potential anticancer agents

Bioorganic & medicinal chemistry, 2022-01, Vol.53, p.116524-116524, Article 116524

2022

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Design, synthesis and evaluation of novel ErbB/HDAC multitargeted inhibitors with selectivity in EGFRT790M mutant cell lines

European journal of medicinal chemistry, 2021-03, Vol.213, p.113173, Article 113173

2021

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Novel synthetic acridine derivatives as potent DNA-binding and apoptosis-inducing antitumor agents

Bioorganic & medicinal chemistry, 2013-07, Vol.21 (14), p.4170-4177

2013

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Discovery of 1-(3-aryl-4-chlorophenyl)-3-(p-aryl)urea derivatives against breast cancer by inhibiting PI3K/Akt/mTOR and Hedgehog signalings

European journal of medicinal chemistry, 2017-12, Vol.141, p.721-733

2017

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Development of a versatile DNMT and HDAC inhibitor C02S modulating multiple cancer hallmarks for breast cancer therapy

Bioorganic chemistry, 2019-06, Vol.87, p.200-208

2019

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SP1 enhances Zbtb7A gene expression via direct binding to GC box in HePG2 cells

BMC research notes, 2009-09, Vol.2 (1), p.175-175

2009

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Antiproliferative activities of the second-generation antipsychotic drug sertindole against breast cancers with a potential application for treatment of breast-to-brain metastases

Scientific reports, 2018-10, Vol.8 (1), p.15753-13, Article 15753

2018

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Molecular design, synthesis and biological research of novel pyridyl acridones as potent DNA-binding and apoptosis-inducing agents

European journal of medicinal chemistry, 2015-03, Vol.93, p.214-226

2015

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Branched rolling circle amplification method for measuring serum circulating micro RNA levels for early breast cancer detection

Cancer science, 2018-09, Vol.109 (9), p.2897-2906

2018

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Metabolic Profiling of Amino Acids by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS) to Characterize the Significance of Glutamine in Triple-Negative Breast Cancer (TNBC)

Analytical letters, 2019-05, Vol.52 (7), p.1068-1082

2019

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Association study of FGF18 with developmental dyslexia in Chinese population

Psychiatric genetics, 2018-02, Vol.28 (1), p.8-11

2018

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Design, synthesis and evaluation of novel ErbB/HDAC multitargeted inhibitors with selectivity in EGFR T790M mutant cell lines

European journal of medicinal chemistry, 2021-03, Vol.213, p.113173

2021

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Olaparib hydroxamic acid derivatives as dual PARP and HDAC inhibitors for cancer therapy

Antitumor Activity of s-Triazine Derivatives: A Systematic Review

Branched rolling circle amplification method for measuring serum circulating microRNA levels for early breast cancer detection

Combined inhibition of HDAC and DNMT1 induces p85α/MEK-mediated cell cycle arrest by dual target inhibitor 208 in U937 cells

Design, synthesis and antitumor evaluations of nucleoside base hydroxamic acid derivatives as DNMT and HDAC dual inhibitors

TRIP13, identified as a hub gene of tumor progression, is the target of microRNA-4693-5p and a potential therapeutic target for colorectal cancer

Design, synthesis and biological evaluation of novel phthalazinone acridine derivatives as dual PARP and Topo inhibitors for potential anticancer agents

IBSP, a potential recurrence biomarker, promotes the progression of colorectal cancer via Fyn/β‐catenin signaling pathway

Exploration of acridine scaffold as a potentially interesting scaffold for discovering novel multi-target VEGFR-2 and Src kinase inhibitors

Discovery of novel nucleoside derivatives as selective lysine acetyltransferase p300 inhibitors for cancer therapy

Current discovery strategies for hepatocellular carcinoma therapeutics

Design, synthesis and anticancer potential of NSC-319745 hydroxamic acid derivatives as DNMT and HDAC inhibitors

Synthesis and biological evaluation of benzimidazole acridine derivatives as potential DNA-binding and apoptosis-inducing agents

Quinazoline-based hydroxamic acid derivatives as dual histone methylation and deacetylation inhibitors for potential anticancer agents

Design, synthesis and evaluation of novel ErbB/HDAC multitargeted inhibitors with selectivity in EGFRT790M mutant cell lines

Novel synthetic acridine derivatives as potent DNA-binding and apoptosis-inducing antitumor agents

Discovery of 1-(3-aryl-4-chlorophenyl)-3-(p-aryl)urea derivatives against breast cancer by inhibiting PI3K/Akt/mTOR and Hedgehog signalings

Development of a versatile DNMT and HDAC inhibitor C02S modulating multiple cancer hallmarks for breast cancer therapy

SP1 enhances Zbtb7A gene expression via direct binding to GC box in HePG2 cells

Antiproliferative activities of the second-generation antipsychotic drug sertindole against breast cancers with a potential application for treatment of breast-to-brain metastases

Molecular design, synthesis and biological research of novel pyridyl acridones as potent DNA-binding and apoptosis-inducing agents

Branched rolling circle amplification method for measuring serum circulating micro RNA levels for early breast cancer detection

Metabolic Profiling of Amino Acids by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS) to Characterize the Significance of Glutamine in Triple-Negative Breast Cancer (TNBC)

Association study of FGF18 with developmental dyslexia in Chinese population

Design, synthesis and evaluation of novel ErbB/HDAC multitargeted inhibitors with selectivity in EGFR T790M mutant cell lines

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