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A computational approach to distinguish somatic vs. germline origin of genomic alterations from deep sequencing of cancer specimens without a matched normal

PLoS computational biology, 2018-02, Vol.14 (2), p.e1005965-e1005965

2018

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A direct characterization of human mutation based on microsatellites

Nature genetics, 2012-10, Vol.44 (10), p.1161-1165

2012

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A Novel Next-Generation Sequencing Approach to Detecting Microsatellite Instability and Pan-Tumor Characterization of 1000 Microsatellite Instability–High Cases in 67,000 Patient Samples

The Journal of molecular diagnostics : JMD, 2019-11, Vol.21 (6), p.1053-1066

2019

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Targeted Next Generation Sequencing Identifies Markers of Response to PD-1 Blockade

Cancer immunology research, 2016-11, Vol.4 (11), p.959-967

2016

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Genomic Profiling of a Large Set of Diverse Pediatric Cancers Identifies Known and Novel Mutations across Tumor Spectra

Cancer research (Chicago, Ill.), 2017-01, Vol.77 (2), p.509-519

2017

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Clinical Actionability of Comprehensive Genomic Profiling for Management of Rare or Refractory Cancers

The oncologist (Dayton, Ohio), 2016-11, Vol.21 (11), p.1315-1325

2016

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Broad Detection of Alterations Predicted to Confer Lack of Benefit From EGFR Antibodies or Sensitivity to Targeted Therapy in Advanced Colorectal Cancer

The oncologist (Dayton, Ohio), 2016-11, Vol.21 (11), p.1306-1314

2016

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Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies

JNCI : Journal of the National Cancer Institute, 2015-02, Vol.107 (2), p.1

2015

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Microsatellites Are Molecular Clocks That Support Accurate Inferences about History

Molecular biology and evolution, 2009-05, Vol.26 (5), p.1017-1027

2009

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Comprehensive Genomic Profiling of Clinically Advanced Medullary Thyroid Carcinoma

Oncology, 2016-01, Vol.90 (6), p.339-346

2016

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The cardiac output from blood pressure algorithms trial

Critical care medicine, 2009, Vol.37 (1), p.72-80

2009

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Abstract 1607: An ERBB2 follow-on companion diagnostic for clinical care of patients with breast cancer

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.1607-1607

2018

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Abstract 417: Comparative analysis of clinically validated NGS-based assays reveals high concordance across short variants

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.417-417

2018

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Abstract 4544: A validated diagnostic assay for identifying ovarian cancer patients with deleterious BRCA mutations and high genomic loss of heterozygosity (LOH)

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.4544-4544

2018

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Abstract 1893: A computational method for somatic versus germline variant status determination from targeted next-generation sequencing of clinical cancer specimens without a matched normal control

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.1893-1893

2014

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Abstract 4757: A clinically validated comprehensive companion diagnostic platform for care of patients with advanced cancer

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.4757-4757

2018

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Abstract A11: NGS-based tumor genomic profiling to identify ovarian cancer patients who benefit from the PARP inhibitor rucaparib

Clinical cancer research, 2016-01, Vol.22 (2_Supplement), p.A11-A11

2016

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Abstract 3394: CGP identifies largely non-overlapping high tumor mutational burden and HRD genomic alterations in 721 clinically advanced prostate acinar adenocarcinoma cases

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3394-3394

2017

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Abstract 611: Exploratory analyses suggest ovarian tumors with somatic or germline loss of function mutations in BRCA1 or BRCA2 are biologically similar and sensitive to PARP inhibition

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.611-611

2015

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Abstract 4927: Next-generation sequencing enables new approach to molecular cytogenetics

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.4927-4927

2015

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A signal abnormality index for arterial blood pressure waveforms

2006 Computers in Cardiology, 2006, p.13-16

2006

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iTAK： A Program for Genome-wide Prediction and Classification of Plant Transcription Factors, Transcriptional Regulators, and Protein Kinases

Molecular plant, 2016-12, Vol.9 (12), p.1667-1670

2016

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The relationship between the chemistry and biological activity of the bisphosphonates

Bone (New York, N.Y.), 2011-07, Vol.49 (1), p.20-33

2011

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A computational approach to distinguish somatic vs. germline origin of genomic alterations from deep sequencing of cancer specimens without a matched normal

BRCA Reversion Mutations in Circulating Tumor DNA Predict Primary and Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma

A direct characterization of human mutation based on microsatellites

A Novel Next-Generation Sequencing Approach to Detecting Microsatellite Instability and Pan-Tumor Characterization of 1000 Microsatellite Instability–High Cases in 67,000 Patient Samples

Targeted Next Generation Sequencing Identifies Markers of Response to PD-1 Blockade

Genomic Profiling of a Large Set of Diverse Pediatric Cancers Identifies Known and Novel Mutations across Tumor Spectra

Clinical Actionability of Comprehensive Genomic Profiling for Management of Rare or Refractory Cancers

Broad Detection of Alterations Predicted to Confer Lack of Benefit From EGFR Antibodies or Sensitivity to Targeted Therapy in Advanced Colorectal Cancer

Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies

Microsatellites Are Molecular Clocks That Support Accurate Inferences about History

Comprehensive Genomic Profiling of Clinically Advanced Medullary Thyroid Carcinoma

The cardiac output from blood pressure algorithms trial

First-in-human trial of multikinase VEGF inhibitor regorafenib and anti-EGFR antibody cetuximab in advanced cancer patients

Abstract 1607: An ERBB2 follow-on companion diagnostic for clinical care of patients with breast cancer

Abstract 417: Comparative analysis of clinically validated NGS-based assays reveals high concordance across short variants

Abstract 4544: A validated diagnostic assay for identifying ovarian cancer patients with deleterious BRCA mutations and high genomic loss of heterozygosity (LOH)

Abstract 1893: A computational method for somatic versus germline variant status determination from targeted next-generation sequencing of clinical cancer specimens without a matched normal control

Abstract 4757: A clinically validated comprehensive companion diagnostic platform for care of patients with advanced cancer

Abstract A11: NGS-based tumor genomic profiling to identify ovarian cancer patients who benefit from the PARP inhibitor rucaparib

Abstract 3394: CGP identifies largely non-overlapping high tumor mutational burden and HRD genomic alterations in 721 clinically advanced prostate acinar adenocarcinoma cases

Abstract 611: Exploratory analyses suggest ovarian tumors with somatic or germline loss of function mutations in BRCA1 or BRCA2 are biologically similar and sensitive to PARP inhibition

Abstract 4927: Next-generation sequencing enables new approach to molecular cytogenetics

A signal abnormality index for arterial blood pressure waveforms

iTAK： A Program for Genome-wide Prediction and Classification of Plant Transcription Factors, Transcriptional Regulators, and Protein Kinases

The relationship between the chemistry and biological activity of the bisphosphonates

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