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Pore-forming activity and structural autoinhibition of the gasdermin family

Nature (London), 2016-07, Vol.535 (7610), p.111-116

2016

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Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase

Journal of medicinal chemistry, 2019-09, Vol.62 (17), p.7923-7940

2019

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Incorporating replacement free energy of binding-site waters in molecular docking

Proteins, structure, function, and bioinformatics, 2014-09, Vol.82 (9), p.1765-1776

2014

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A motif in LILRB2 critical for Angptl2 binding and activation

Blood, 2014-08, Vol.124 (6), p.924-935

2014

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Identification and characterization of an unexpected isomerization motif in CDRH2 that affects antibody activity

mAbs, 2023, Vol.15 (1), p.2215364-2215364

2023

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Erratum: Pore-forming activity and structural autoinhibition of the gasdermin family

Nature (London), 2016-12, Vol.540 (7631), p.150-150

2016

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BGB-A445, a novel non-ligand-blocking agonistic anti-OX40 antibody, exhibits superior immune activation and antitumor effects in preclinical models

Frontiers of medicine, 2023-12, Vol.17 (6), p.1170-1185

2023

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A gain-of-function mutation in Tnni2 impeded bone development through increasing Hif3a expression in DA2B mice

PLoS genetics, 2014-10, Vol.10 (10), p.e1004589-e1004589

2014

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699 A differentiated anti-OX40 agonist BGB-A445 does not block OX40-OX40L interaction and reveals remarkable anti-tumor efficacy in preclinical models

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A741-A741

2020

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High‐Performance 3D Stacked Micro All‐Solid‐State Thin‐Film Lithium‐Ion Batteries Based on the Stress‐Compensation Effect

Small (Weinheim an der Bergstrasse, Germany), 2024-06, Vol.20 (25), p.e2307250-n/a

2024

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Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy

Blood, 2024-05, Vol.143 (18), p.1825-1836

2024

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Discovery of the Clinical Candidate Sonrotoclax (BGB-11417), a Highly Potent and Selective Inhibitor for Both WT and G101V Mutant Bcl‑2

Journal of medicinal chemistry, 2024-05, Vol.67 (10), p.7836-7858

2024

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Intermolecular Interactions between Coencapsulated Drugs Inhibit Drug Crystallization and Enhance Colloidal Stability of Polymeric Micelles

Molecular pharmaceutics, 2017-10, Vol.14 (10), p.3568-3576

2017

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Discovery of BGB-8035, a Highly Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase for B‑Cell Malignancies and Autoimmune Diseases

Journal of medicinal chemistry, 2023-03, Vol.66 (6), p.4025-4044

2023

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Incorporating replacement free energy of binding-site waters in molecular docking: Incorporating Waters in Molecular Docking

Proteins, structure, function, and bioinformatics, 2014-09, Vol.82 (9), p.1765-1776

2014

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Theoretical Studies of the Base Pair Fidelity of Selenium-Modified DNA

The journal of physical chemistry. B, 2011-08, Vol.115 (33), p.10041-10048

2011

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Research on sub-system of anti-lightning discrete digital interface based on SiP

2017 18th International Conference on Electronic Packaging Technology (ICEPT), 2017, p.496-500

2017

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Abstract 5541: BGB-15025, a potent and selective HPK1 inhibitor, is efficacious as a single agent or in combination with PD-1 antibody in multiple tumor models

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.5541-5541

2022

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Abstract 2371: BGB-B167, a first-in-class 4-1BB/CEACAM5 bispecific antibody, exhibits potent in vitro and < for vivo antitumor activity and < for superior safety profile in preclinical models

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.2371-2371

2024

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A Gain-of-Function Mutation in Tnni2 Impeded Bone Development through Increasing Hif3a Expression in DA2B Mice: e1004589

PLoS genetics, 2014-10, Vol.10 (10)

2014

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3D Stacked Micro Thin-Film Lithium-Ion Batteries for Improving Both Specific Capacity and Cycling Life

2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers), 2023, p.1216-1219

2023

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Identification and characterization of an unexpected isomerization motif in CDRH2 that affects antibody activity

mAbs, 2023, Vol.15 (1)

2023

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DFT-based rate equation for thermochemical redox kinetics in a bubbling-fluidized bed reactor and its application to a manganese oxygen carrier in chemical looping

Proceedings of the Combustion Institute, 2024, Vol.40 (1-4), p.105646, Article 105646

2024

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OsGRETCHENHAGEN3-2 modulates rice seed storability via accumulation of abscisic acid and protective substances

Plant physiology (Bethesda), 2021-05, Vol.186 (1), p.469-482

2021

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Pore-forming activity and structural autoinhibition of the gasdermin family

Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase

Incorporating replacement free energy of binding-site waters in molecular docking

A motif in LILRB2 critical for Angptl2 binding and activation

Identification and characterization of an unexpected isomerization motif in CDRH2 that affects antibody activity

Erratum: Pore-forming activity and structural autoinhibition of the gasdermin family

BGB-A445, a novel non-ligand-blocking agonistic anti-OX40 antibody, exhibits superior immune activation and antitumor effects in preclinical models

A gain-of-function mutation in Tnni2 impeded bone development through increasing Hif3a expression in DA2B mice

699 A differentiated anti-OX40 agonist BGB-A445 does not block OX40-OX40L interaction and reveals remarkable anti-tumor efficacy in preclinical models

High‐Performance 3D Stacked Micro All‐Solid‐State Thin‐Film Lithium‐Ion Batteries Based on the Stress‐Compensation Effect

Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy

Discovery of the Clinical Candidate Sonrotoclax (BGB-11417), a Highly Potent and Selective Inhibitor for Both WT and G101V Mutant Bcl‑2

Intermolecular Interactions between Coencapsulated Drugs Inhibit Drug Crystallization and Enhance Colloidal Stability of Polymeric Micelles

Discovery of BGB-8035, a Highly Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase for B‑Cell Malignancies and Autoimmune Diseases

Incorporating replacement free energy of binding-site waters in molecular docking: Incorporating Waters in Molecular Docking

Theoretical Studies of the Base Pair Fidelity of Selenium-Modified DNA

Research on sub-system of anti-lightning discrete digital interface based on SiP

Abstract 5541: BGB-15025, a potent and selective HPK1 inhibitor, is efficacious as a single agent or in combination with PD-1 antibody in multiple tumor models

Abstract 2371: BGB-B167, a first-in-class 4-1BB/CEACAM5 bispecific antibody, exhibits potent in vitro and < for vivo antitumor activity and < for superior safety profile in preclinical models

BTK Leu528Trp - a Potential Secondary Resistance Mechanism Specific for Patients with Chronic Lymphocytic Leukemia Treated with the Next Generation BTK Inhibitor Zanubrutinib

A Gain-of-Function Mutation in Tnni2 Impeded Bone Development through Increasing Hif3a Expression in DA2B Mice: e1004589

3D Stacked Micro Thin-Film Lithium-Ion Batteries for Improving Both Specific Capacity and Cycling Life

Identification and characterization of an unexpected isomerization motif in CDRH2 that affects antibody activity

DFT-based rate equation for thermochemical redox kinetics in a bubbling-fluidized bed reactor and its application to a manganese oxygen carrier in chemical looping

OsGRETCHENHAGEN3-2 modulates rice seed storability via accumulation of abscisic acid and protective substances

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