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USP14 is a deubiquitinase for Ku70 and critical determinant of non-homologous end joining repair in autophagy and PTEN-deficient cells

Nucleic acids research, 2020-01, Vol.48 (2), p.736

2020

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The mitotic kinesin KIF11 is a driver of invasion, proliferation, and self-renewal in glioblastoma

Science translational medicine, 2015-09, Vol.7 (304), p.304ra143

2015

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Deubiquitinase USP37 Is Activated by CDK2 to Antagonize APCCᴰᴴ¹ and Promote S Phase Entry

Molecular cell, 2011-05, Vol.42 (4), p.511-523

2011

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The STARD9/Kif16a Kinesin Associates with Mitotic Microtubules and Regulates Spindle Pole Assembly

Cell, 2011-12, Vol.147 (6), p.1309-1323

2011

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The Unique N Terminus of the UbcH10 E2 Enzyme Controls the Threshold for APC Activation and Enhances Checkpoint Regulation of the APC

Molecular cell, 2008-08, Vol.31 (4), p.544-556

2008

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TRIB1 confers therapeutic resistance in GBM cells by activating the ERK and Akt pathways

Scientific reports, 2023-08, Vol.13 (1), p.12424-12424, Article 12424

2023

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Skp1-Cul1-F-box Ubiquitin Ligase (SCFβTrCP)-mediated Destruction of the Ubiquitin-specific Protease USP37 during G2-phase Promotes Mitotic Entry

The Journal of biological chemistry, 2012-11, Vol.287 (46), p.39021-39029

2012

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Phosphorylation Regulates the p31Comet-Mitotic Arrest-deficient 2 (Mad2) Interaction to Promote Spindle Assembly Checkpoint (SAC) Activity

The Journal of biological chemistry, 2014-04, Vol.289 (16), p.11367-11373

2014

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Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia

Journal of hematology and oncology, 2021-01, Vol.14 (1), p.17-21, Article 17

2021

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Improving Localized Radiotherapy for Glioblastoma via Small Molecule Inhibition of KIF11

Cancers, 2023-06, Vol.15 (12), p.3173

2023

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Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor

Genes & development, 2006-09, Vol.20 (17), p.2410-2420

2006

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The DNA Damage Response in Telophase: Challenging Dogmas

BioEssays, 2020-07, Vol.42 (7), p.e2000085-n/a

Summers, Matthew K.

2020

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Walking the tightrope between DNA damage repair and genomic integrity

Neuro-oncology (Charlottesville, Va.), 2024-03, Vol.26 (3), p.399-400

2024

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APC/C ubiquitin ligase: Functions and mechanisms in tumorigenesis

Seminars in cancer biology, 2020-12, Vol.67 (Pt 2), p.80-91

2020

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Editorial: Ubiquitin-Modifying Enzymes as Drug Targets and Biomarkers in Cancer

Frontiers in oncology, 2021-09, Vol.11, p.758983-758983

2021

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USP14 regulates DNA damage repair by targeting RNF168-dependent ubiquitination

Autophagy, 2018-11, Vol.14 (11), p.1976-1990

2018

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A Role for the Anaphase-Promoting Complex Inhibitor Emi2/XErp1, a Homolog of Early Mitotic Inhibitor 1, in Cytostatic Factor Arrest of Xenopus Eggs

Proceedings of the National Academy of Sciences - PNAS, 2005-03, Vol.102 (12), p.4318-4323

2005

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A sumoylation program is essential for maintaining the mitotic fidelity in proliferating mantle cell lymphoma cells

Experimental hematology & oncology, 2022-07, Vol.11 (1), p.1-19, Article 40

2022

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The CHFR mitotic checkpoint protein delays cell cycle progression by excluding Cyclin B1 from the nucleus

Oncogene, 2005-04, Vol.24 (16), p.2589-2598

2005

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MKLP2 functions in early mitosis to ensure proper chromosome congression

Journal of cell science, 2022-06, Vol.135 (12)

2022

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Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry

Molecular cell, 2011-05, Vol.42 (4), p.511-523

2011

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Hyperphosphorylation of CDH1 in Glioblastoma Cancer Stem Cells Attenuates APC/CCDH1 Activity and Pharmacologic Inhibition of APC/CCDH1/CDC20 Compromises Viability

Molecular cancer research, 2019-07, Vol.17 (7), p.1519-1530

2019

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Hyperphosphorylation of CDH1 in Glioblastoma Cancer Stem Cells Attenuates APC/C CDH1 Activity and Pharmacologic Inhibition of APC/C CDH1/CDC20 Compromises Viability

Molecular cancer research, 2019-07, Vol.17 (7), p.1519

2019

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LIN9 and NEK2 Are Core Regulators of Mitotic Fidelity That Can Be Therapeutically Targeted to Overcome Taxane Resistance

Cancer research (Chicago, Ill.), 2020-04, Vol.80 (8), p.1693-1706

2020

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The small molecule drug CBL0137 increases the level of DNA damage and the efficacy of radiotherapy for glioblastoma

Cancer letters, 2021-02, Vol.499, p.232-242

2021

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USP14 is a deubiquitinase for Ku70 and critical determinant of non-homologous end joining repair in autophagy and PTEN-deficient cells

The mitotic kinesin KIF11 is a driver of invasion, proliferation, and self-renewal in glioblastoma

Deubiquitinase USP37 Is Activated by CDK2 to Antagonize APCCᴰᴴ¹ and Promote S Phase Entry

The STARD9/Kif16a Kinesin Associates with Mitotic Microtubules and Regulates Spindle Pole Assembly

The Unique N Terminus of the UbcH10 E2 Enzyme Controls the Threshold for APC Activation and Enhances Checkpoint Regulation of the APC

TRIB1 confers therapeutic resistance in GBM cells by activating the ERK and Akt pathways

Skp1-Cul1-F-box Ubiquitin Ligase (SCFβTrCP)-mediated Destruction of the Ubiquitin-specific Protease USP37 during G2-phase Promotes Mitotic Entry

Phosphorylation Regulates the p31Comet-Mitotic Arrest-deficient 2 (Mad2) Interaction to Promote Spindle Assembly Checkpoint (SAC) Activity

Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia

Improving Localized Radiotherapy for Glioblastoma via Small Molecule Inhibition of KIF11

Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor

The DNA Damage Response in Telophase: Challenging Dogmas

Walking the tightrope between DNA damage repair and genomic integrity

APC/C ubiquitin ligase: Functions and mechanisms in tumorigenesis

Editorial: Ubiquitin-Modifying Enzymes as Drug Targets and Biomarkers in Cancer

USP14 regulates DNA damage repair by targeting RNF168-dependent ubiquitination

A Role for the Anaphase-Promoting Complex Inhibitor Emi2/XErp1, a Homolog of Early Mitotic Inhibitor 1, in Cytostatic Factor Arrest of Xenopus Eggs

A sumoylation program is essential for maintaining the mitotic fidelity in proliferating mantle cell lymphoma cells

The CHFR mitotic checkpoint protein delays cell cycle progression by excluding Cyclin B1 from the nucleus

MKLP2 functions in early mitosis to ensure proper chromosome congression

Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry

Hyperphosphorylation of CDH1 in Glioblastoma Cancer Stem Cells Attenuates APC/CCDH1 Activity and Pharmacologic Inhibition of APC/CCDH1/CDC20 Compromises Viability

Hyperphosphorylation of CDH1 in Glioblastoma Cancer Stem Cells Attenuates APC/C CDH1 Activity and Pharmacologic Inhibition of APC/C CDH1/CDC20 Compromises Viability

LIN9 and NEK2 Are Core Regulators of Mitotic Fidelity That Can Be Therapeutically Targeted to Overcome Taxane Resistance

The small molecule drug CBL0137 increases the level of DNA damage and the efficacy of radiotherapy for glioblastoma

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