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Structure–activity study of novel tricyclic benzazepine arginine vasopressin antagonists

Bioorganic & medicinal chemistry letters, 2003-07, Vol.13 (13), p.2195-2198

2003

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IκBα Kinase Inhibitor IKI-1 Conferred Tumor Necrosis Factor α Sensitivity to Pancreatic Cancer Cells and a Xenograft Tumor Model

Cancer research (Chicago, Ill.), 2008-11, Vol.68 (22), p.9519-9524

2008

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Inhibition of Cytosolic Phospholipase A2α: Hit to Lead Optimization

Journal of medicinal chemistry, 2006-01, Vol.49 (1), p.135-158

2006

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Synthesis and biological evaluation of tricyclic anilinopyrimidines as IKKβ inhibitors

Bioorganic & medicinal chemistry letters, 2010-06, Vol.20 (12), p.3821-3825

2010

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Structure-Activity Relationship of 6-Methylidene Penems Bearing 6,5 Bicyclic Heterocycles as Broad-Spectrum β-Lactamase Inhibitors: Evidence for 1,4-Thiazepine Intermediates with C7 R Stereochemistry by Computational Methods

Journal of medicinal chemistry, 2006-07, Vol.49 (15), p.4623-4637

2006

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Cyclic amine sulfonamides as linkers in the design and synthesis of novel human β3 adrenergic receptor agonists

Bioorganic & medicinal chemistry letters, 2003-07, Vol.13 (13), p.2191-2194

2003

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Novel (4-piperidin-1-yl)-phenyl sulfonamides as potent and selective human β3 agonists

Bioorganic & medicinal chemistry, 2001-08, Vol.9 (8), p.2045-2059

2001

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5-Fluoro-2-methyl-N-[4-(5H-pyrrolo[2,1-c]- [1,4]benzodiazepin-10(11H)-ylcarbonyl)-3- chlorophenyl]benzamide (VPA-985): An Orally Active Arginine Vasopressin Antagonist with Selectivity for V2 Receptors

Journal of medicinal chemistry, 1998-07, Vol.41 (14), p.2442-2444

1998

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2,4-Thiazolidinediones as potent and selective human β3 agonists

Bioorganic & medicinal chemistry letters, 2001-03, Vol.11 (6), p.757-760

2001

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ChemInform Abstract: 1‐(2,6,6‐TRIMETHYL‐4‐HYDROXYCYCLOHEXENYL)‐1,3‐BUTANEDIONE, AN EXTRACELLULAR METABOLITE FROM THE DINOFLAGELLATE PROROCENTRUM MINIMUM

Chemischer Informationsdienst, 1980-07, Vol.11 (27)

1980

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Structure-Activity Study of Novel Tricyclic Benzazepine Arginine Vasopressin Antagonists

ChemInform, 2003-10, Vol.34 (42), p.no-no

2003

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Cyclic Amine Sulfonamides as Linkers in the Design and Synthesis of Novel Human β3 Adrenergic Receptor Agonists

ChemInform, 2003-10, Vol.34 (41), p.no-no

2003

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5-Fluoro-2-methyl- N -[4-(5 H -pyrrolo[2,1- c ]- [1,4]benzodiazepin-10(11 H )-ylcarbonyl)-3- chlorophenyl]benzamide (VPA-985): An Orally Active Arginine Vasopressin Antagonist with Selectivity for V 2 Receptors

Journal of medicinal chemistry, 1998-07, Vol.41 (14), p.2442-2444

1998

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Bromination of 3-cyclopentyl-2-butenolide

Journal of organic chemistry, 1979-03, Vol.44 (6), p.1012-1014

1979

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Cyclic amine sulfonamides as linkers in the design and synthesis of novel human beta(3) adrenergic receptor agonists

Bioorganic & medicinal chemistry letters, 2003-07, Vol.13 (13), p.2191-2194

2003

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Inhibition of cytosolic phospholipase A2alpha: hit to lead optimization

Journal of medicinal chemistry, 2006-01, Vol.49 (1), p.135-158

2006

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Inhibition of Cytosolic Phospholipase A 2 α: Hit to Lead Optimization

Journal of medicinal chemistry, 2006-01, Vol.49 (1), p.135-158

2006

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Synthesis and biological evaluation of tricyclic anilinopyrimidines as IKKbeta inhibitors

Bioorganic & medicinal chemistry letters, 2010-06, Vol.20 (12), p.3821-3825

2010

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Cyclic amine sulfonamides as linkers in the design and synthesis of novel human β 3 adrenergic receptor agonists

Bioorganic & medicinal chemistry letters, 2003, Vol.13 (13), p.2191-2194

2003

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(4-Piperidin-1-yl)phenyl Amides: Potent and Selective Human β3 Agonists

Journal of medicinal chemistry, 2001-04, Vol.44 (9), p.1456-1466

2001

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IkappaBalpha kinase inhibitor IKI-1 conferred tumor necrosis factor alpha sensitivity to pancreatic cancer cells and a xenograft tumor model

Cancer research (Chicago, Ill.), 2008-11, Vol.68 (22), p.9519-9524

2008

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(4-Piperidin-1-yl)phenyl Amides: Potent and Selective Human β 3 Agonists

Journal of medicinal chemistry, 2001-04, Vol.44 (9), p.1456-1466

2001

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Indole Cytosolic Phospholipase A2 α Inhibitors: Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic Acid, Efipladib

Structure–activity study of novel tricyclic benzazepine arginine vasopressin antagonists

IκBα Kinase Inhibitor IKI-1 Conferred Tumor Necrosis Factor α Sensitivity to Pancreatic Cancer Cells and a Xenograft Tumor Model

Inhibition of Cytosolic Phospholipase A2α: Hit to Lead Optimization

Synthesis and biological evaluation of tricyclic anilinopyrimidines as IKKβ inhibitors

Structure-Activity Relationship of 6-Methylidene Penems Bearing 6,5 Bicyclic Heterocycles as Broad-Spectrum β-Lactamase Inhibitors: Evidence for 1,4-Thiazepine Intermediates with C7 R Stereochemistry by Computational Methods

Cyclic amine sulfonamides as linkers in the design and synthesis of novel human β3 adrenergic receptor agonists

Novel (4-piperidin-1-yl)-phenyl sulfonamides as potent and selective human β3 agonists

5-Fluoro-2-methyl-N-[4-(5H-pyrrolo[2,1-c]- [1,4]benzodiazepin-10(11H)-ylcarbonyl)-3- chlorophenyl]benzamide (VPA-985): An Orally Active Arginine Vasopressin Antagonist with Selectivity for V2 Receptors

2,4-Thiazolidinediones as potent and selective human β3 agonists

ChemInform Abstract: 1‐(2,6,6‐TRIMETHYL‐4‐HYDROXYCYCLOHEXENYL)‐1,3‐BUTANEDIONE, AN EXTRACELLULAR METABOLITE FROM THE DINOFLAGELLATE PROROCENTRUM MINIMUM

Structure-Activity Study of Novel Tricyclic Benzazepine Arginine Vasopressin Antagonists

Cyclic Amine Sulfonamides as Linkers in the Design and Synthesis of Novel Human β3 Adrenergic Receptor Agonists

5-Fluoro-2-methyl- N -[4-(5 H -pyrrolo[2,1- c ]- [1,4]benzodiazepin-10(11 H )-ylcarbonyl)-3- chlorophenyl]benzamide (VPA-985): An Orally Active Arginine Vasopressin Antagonist with Selectivity for V 2 Receptors

Bromination of 3-cyclopentyl-2-butenolide

Cyclic amine sulfonamides as linkers in the design and synthesis of novel human beta(3) adrenergic receptor agonists

Indole Cytosolic Phospholipase A 2 α Inhibitors: Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1 H -indol-3-yl]propyl}benzoic Acid, Efipladib

Indole Cytosolic Phospholipase A2 α Inhibitors : Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-l-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic Acid, Efipladib

Inhibition of cytosolic phospholipase A2alpha: hit to lead optimization

Inhibition of Cytosolic Phospholipase A 2 α: Hit to Lead Optimization

Synthesis and biological evaluation of tricyclic anilinopyrimidines as IKKbeta inhibitors

Cyclic amine sulfonamides as linkers in the design and synthesis of novel human β 3 adrenergic receptor agonists

(4-Piperidin-1-yl)phenyl Amides: Potent and Selective Human β3 Agonists

IkappaBalpha kinase inhibitor IKI-1 conferred tumor necrosis factor alpha sensitivity to pancreatic cancer cells and a xenograft tumor model

(4-Piperidin-1-yl)phenyl Amides: Potent and Selective Human β 3 Agonists

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