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BH3 Domains of BH3-Only Proteins Differentially Regulate Bax-Mediated Mitochondrial Membrane Permeabilization Both Directly and Indirectly

Molecular cell, 2005-02, Vol.17 (4), p.525-535

2005

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Immune Complex Formation Is Associated With Loss of Tolerance and an Antibody Response to Both Drug and Target

Frontiers in immunology, 2021-12, Vol.12, p.782788-782788

2021

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Prednisolone reduces the interferon response to AAV in cynomolgus macaques and may increase liver gene expression

Molecular therapy. Methods & clinical development, 2022-03, Vol.24, p.292-305

2022

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Design of Natural Killer T Cell Activators: Structure and Function of a Microbial Glycosphingolipid Bound to Mouse CD1d

Proceedings of the National Academy of Sciences - PNAS, 2006-03, Vol.103 (11), p.3972-3977

2006

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Safety and Biological Activity of Rozibafusp alfa, a Bispecific Inhibitor of Inducible Costimulator Ligand and B Cell Activating Factor, in Patients With Rheumatoid Arthritis: Results of a Phase 1b, Randomized, Double‐Blind, Placebo‐Controlled, Multiple Ascending Dose Study

ACR open rheumatology, 2022-10, Vol.4 (10), p.903-911

2022

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Efficacy and safety of abrilumab, an α4β7 integrin inhibitor, in Japanese patients with moderate-to-severe ulcerative colitis: a phase II study

Intestinal research, 2019, 17(3), , pp.375-386

2019

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Efficacy and Safety of Abrilumab in a Randomized, Placebo-Controlled Trial for Moderate-to-Severe Ulcerative Colitis

Gastroenterology (New York, N.Y. 1943), 2019-03, Vol.156 (4), p.946-957.e18

2019

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Brief Report: A Randomized, Double‐Blind, Parallel‐Group, Placebo‐Controlled, Multiple‐Dose Study to Evaluate AMG 557 in Patients With Systemic Lupus Erythematosus and Active Lupus Arthritis

Arthritis & rheumatology (Hoboken, N.J.), 2018-07, Vol.70 (7), p.1071-1076

2018

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Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti–Interferon‐γ Antibody, in Patients With Discoid Lupus Erythematosus

Arthritis & rheumatology (Hoboken, N.J.), 2017-05, Vol.69 (5), p.1028-1034

2017

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Prednisolone and rapamycin reduce the plasma cell gene signature and may improve AAV gene therapy in cynomolgus macaques

Gene therapy, 2024-03, Vol.31 (3-4), p.128-143

2024

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Identification of Pre- and Postselection TCRαβ + Intraepithelial Lymphocyte Precursors in the Thymus

Immunity (Cambridge, Mass.), 2006-10, Vol.25 (4), p.631-641

2006

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Mechanisms for Glycolipid Antigen-Driven Cytokine Polarization by Vα14 i NKT Cells

The Journal of immunology (1950), 2010-01, Vol.184 (1), p.141-153

2010

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Activation or anergy: NKT cells are stunned by alpha-galactosylceramide

The Journal of clinical investigation, 2005-09, Vol.115 (9), p.2328-2329

2005

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Co-receptor choice by Vα14 i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection

The Journal of experimental medicine, 2010-05, Vol.207 (5), p.1015-1029

2010

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Efficacy and Safety of Abrilumab (AMG 181/MEDI 7183) Therapy for Moderate to Severe Crohn’s Disease

Gastroenterology (New York, N.Y. 1943), 2017-04, Vol.152 (5), p.S598-S598

2017

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Safety, pharmacokinetics and pharmacodynamics of AMG 811, an anti-interferon-γ monoclonal antibody, in SLE subjects without or with lupus nephritis

Lupus science & medicine, 2017-09, Vol.4 (1), p.e000226

2017

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A modified α-galactosyl ceramide for staining and stimulating natural killer T cells

Journal of immunological methods, 2006-05, Vol.312 (1), p.34-39

2006

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Clinical pharmacology of AMG 181, a gut‐specific human anti‐α4β7 monoclonal antibody, for treating inflammatory bowel diseases

British journal of clinical pharmacology, 2014-12, Vol.78 (6), p.1315-1333

2014

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Efficacy and Safety of Abrilumab in Subjects with Moderate to Severe Ulcerative Colitis: Results of a Phase 2B, Randomized, Double-Blind, Multiple-Dose, Placebo-Controlled Study

Gastroenterology (New York, N.Y. 1943), 2017-04, Vol.152 (5), p.S198-S198

2017

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Acid Test: Lipid Antigens Get into the Groove

Immunity (Cambridge, Mass.), 2008-06, Vol.28 (6), p.727-729

2008

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Sa1206 Multiple-Dose Pharmacokinetics (PK), Pharmacodynamics (PD), and Safety of AMG 181, a Human Anti-a4β7 Antibody for Treating Inflammatory Bowel Diseases (IBD)

Gastroenterology (New York, N.Y. 1943), 2013-05, Vol.144 (5), p.S-229-S-229

2013

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Sa1207 Pharmacokinetics/Pharmacodynamics (PK/PD), Efficacy, and Safety of AMG 181 in Subjects With Active, Mild to Moderate Ulcerative Colitis - An Initial Assessment

Gastroenterology (New York, N.Y. 1943), 2013-05, Vol.144 (5), p.S-230-S-230

2013

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Su2082 Pharmacokinetics (PK), Pharmacodynamics (PD), and Safety of Amg 181, a Fully Human Anti-α4β7 Antibody for Treating Inflammatory Bowel Diseases (IBD)

Gastroenterology (New York, N.Y. 1943), 2012-05, Vol.142 (5), p.S-565-S-565

2012

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Positive Selection of a Qa-1-Restricted T Cell Receptor with Specificity for Insulin

Immunity (Cambridge, Mass.), 2002-07, Vol.17 (1), p.95-105

2002

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CD1 and MHC II find different means to the same end

Trends in immunology, 2005-05, Vol.26 (5), p.282-288

2005

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BH3 Domains of BH3-Only Proteins Differentially Regulate Bax-Mediated Mitochondrial Membrane Permeabilization Both Directly and Indirectly

Immune Complex Formation Is Associated With Loss of Tolerance and an Antibody Response to Both Drug and Target

Prednisolone reduces the interferon response to AAV in cynomolgus macaques and may increase liver gene expression

Design of Natural Killer T Cell Activators: Structure and Function of a Microbial Glycosphingolipid Bound to Mouse CD1d

Safety and Biological Activity of Rozibafusp alfa, a Bispecific Inhibitor of Inducible Costimulator Ligand and B Cell Activating Factor, in Patients With Rheumatoid Arthritis: Results of a Phase 1b, Randomized, Double‐Blind, Placebo‐Controlled, Multiple Ascending Dose Study

Efficacy and safety of abrilumab, an α4β7 integrin inhibitor, in Japanese patients with moderate-to-severe ulcerative colitis: a phase II study

Efficacy and Safety of Abrilumab in a Randomized, Placebo-Controlled Trial for Moderate-to-Severe Ulcerative Colitis

Brief Report: A Randomized, Double‐Blind, Parallel‐Group, Placebo‐Controlled, Multiple‐Dose Study to Evaluate AMG 557 in Patients With Systemic Lupus Erythematosus and Active Lupus Arthritis

Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti–Interferon‐γ Antibody, in Patients With Discoid Lupus Erythematosus

Prednisolone and rapamycin reduce the plasma cell gene signature and may improve AAV gene therapy in cynomolgus macaques

Identification of Pre- and Postselection TCRαβ + Intraepithelial Lymphocyte Precursors in the Thymus

Mechanisms for Glycolipid Antigen-Driven Cytokine Polarization by Vα14 i NKT Cells

Activation or anergy: NKT cells are stunned by alpha-galactosylceramide

Co-receptor choice by Vα14 i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection

Efficacy and Safety of Abrilumab (AMG 181/MEDI 7183) Therapy for Moderate to Severe Crohn’s Disease

Safety, pharmacokinetics and pharmacodynamics of AMG 811, an anti-interferon-γ monoclonal antibody, in SLE subjects without or with lupus nephritis

A modified α-galactosyl ceramide for staining and stimulating natural killer T cells

Clinical pharmacology of AMG 181, a gut‐specific human anti‐α4β7 monoclonal antibody, for treating inflammatory bowel diseases

Efficacy and Safety of Abrilumab in Subjects with Moderate to Severe Ulcerative Colitis: Results of a Phase 2B, Randomized, Double-Blind, Multiple-Dose, Placebo-Controlled Study

Acid Test: Lipid Antigens Get into the Groove

Sa1206 Multiple-Dose Pharmacokinetics (PK), Pharmacodynamics (PD), and Safety of AMG 181, a Human Anti-a4β7 Antibody for Treating Inflammatory Bowel Diseases (IBD)

Sa1207 Pharmacokinetics/Pharmacodynamics (PK/PD), Efficacy, and Safety of AMG 181 in Subjects With Active, Mild to Moderate Ulcerative Colitis - An Initial Assessment

Su2082 Pharmacokinetics (PK), Pharmacodynamics (PD), and Safety of Amg 181, a Fully Human Anti-α4β7 Antibody for Treating Inflammatory Bowel Diseases (IBD)

Positive Selection of a Qa-1-Restricted T Cell Receptor with Specificity for Insulin

CD1 and MHC II find different means to the same end

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