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Potential role of peroxisome proliferator-activated receptor-α in the modulation of glucose-stimulated insulin secretion

Diabetes (New York, N.Y.), 2004-02, Vol.53 (suppl_1), p.S71-S81

2004

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Gender-specific programming of insulin secretion and action

Journal of endocrinology, 2002-12, Vol.175 (3), p.757-767

2002

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Regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation

Biochemical Society transactions, 2003-12, Vol.31 (Pt 6), p.1143-1151

2003

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Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs

American journal of physiology: endocrinology and metabolism, 2003-05, Vol.284 (5), p.E855-E862

2003

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Early growth retardation induced by excessive exposure to glucocorticoids in utero selectively increases cardiac GLUT1 protein expression and Akt/protein kinase B activity in adulthood

Journal of endocrinology, 2001-04, Vol.169 (1), p.11-22

2001

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Targeted upregulation of pyruvate dehydrogenase kinase (PDK)-4 in slow-twitch skeletal muscle underlies the stable modification of the regulatory characteristics of PDK induced by high-fat feeding

Diabetes (New York, N.Y.), 2000-05, Vol.49 (5), p.775-781

2000

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Acute (24 h) activation of peroxisome proliferator-activated receptor-alpha (PPARalpha) reverses high-fat feeding-induced insulin hypersecretion in vivo and in perifused pancreatic islets

Journal of endocrinology, 2003-05, Vol.177 (2), p.197-205

2003

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Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin

Biochemical journal, 2002-06, Vol.364 (Pt 2), p.361-368

2002

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Enhanced placental GLUT1 and GLUT3 expression in dexamethasone-induced fetal growth retardation

Molecular and cellular endocrinology, 2001-12, Vol.185 (1), p.109-117

2001

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Early-life programming of susceptibility to dysregulation of glucose metabolism and the development of Type 2 diabetes mellitus

Biochemical journal, 2000-08, Vol.349 Pt 3 (3), p.657-665

2000

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Maternal glucocorticoid treatment modulates placental leptin and leptin receptor expression and materno-fetal leptin physiology during late pregnancy, and elicits hypertension associated with hyperleptinaemia in the early-growth-retarded adult offspring

European journal of endocrinology, 2001-10, Vol.145 (4), p.529-539

2001

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PDK4: A factor in fatness?

Obesity (Silver Spring, Md.), 2003-02, Vol.11 (2), p.167-169

Sugden, M.C

2003

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Investigation of potential mechanisms regulating protein expression of hepatic pyruvate dehydrogenase kinase isoforms 2 and 4 by fatty acids and thyroid hormone

Biochemical journal, 2003-02, Vol.369 (Pt 3), p.687-695

2003

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Diabetogenic Impact of Long-Chain ω-3 Fatty Acids on Pancreatic β-Cell Function and the Regulation of Endogenous Glucose Production

Endocrinology (Philadelphia), 2003-09, Vol.144 (9), p.3958-3968

2003

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Fibre-type specific modification of the activity and regulation of skeletal muscle pyruvate dehydrogenase kinase (PDK) by prolonged starvation and refeeding is associated with targeted regulation of PDK isoenzyme 4 expression

Biochemical journal, 2000-03, Vol.346 Pt 3 (3), p.651-657

2000

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Selective modification of the pyruvate dehydrogenase kinase isoform profile in skeletal muscle in hyperthyroidism: implications for the regulatory impact of glucose on fatty acid oxidation

Journal of endocrinology, 2000-11, Vol.167 (2), p.339-345

2000

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Acute ω-3 Fatty Acid Enrichment Selectively Reverses High-Saturated Fat Feeding-Induced Insulin Hypersecretion But Does Not Improve Peripheral Insulin Resistance

Diabetes (New York, N.Y.), 2004-02, Vol.53 (suppl 1), p.S166-S171

2004

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Up-regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) protein expression in oxidative skeletal muscle does not require the obligatory participation of peroxisome-proliferator-activated receptor alpha (PPARalpha)

Biochemical journal, 2002-09, Vol.366 (Pt 3), p.839-846

2002

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Evaluation of the role of peroxisome-proliferator-activated receptor alpha in the regulation of cardiac pyruvate dehydrogenase kinase 4 protein expression in response to starvation, high-fat feeding and hyperthyroidism

Biochemical journal, 2002-06, Vol.364 (Pt 3), p.687-694

2002

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Selective modification of pyruvate dehydrogenase kinase isoform expression in rat pancreatic islets elicited by starvation and activation of peroxisome proliferator-activated receptor-α implications for glucose-stimulated insulin secretion

Diabetes (New York, N.Y.), 2001-12, Vol.50 (12), p.2729-2736

2001

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Expression and regulation of pyruvate dehydrogenase kinase isoforms in the developing rat heart and in adulthood: role of thyroid hormone status and lipid supply

Biochemical journal, 2000-12, Vol.352 Pt 3 (3), p.731-738

2000

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Interactive influences of peroxisome proliferator-activated receptor alpha activation and glucocorticoids on pancreatic beta cell compensation in insulin resistance induced by dietary saturated fat in the rat

Diabetologia, 2005-10, Vol.48 (10), p.2062-2068

2005

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Role of Peroxisome Proliferator-Activated Receptor-α in the Mechanism Underlying Changes in Renal Pyruvate Dehydrogenase Kinase Isoform 4 Protein Expression in Starvation and after Refeeding

Archives of biochemistry and biophysics, 2001-11, Vol.395 (2), p.246-252

2001

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Current concepts concerning the role of leptin in reproductive function

Molecular and cellular endocrinology, 1999-11, Vol.157 (1), p.11-20

1999

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Effects of prenatal glucocorticoid exposure on cardiac calreticulin and calsequestrin protein expression during early development and in adulthood

Biochemical journal, 2003-04, Vol.371 (Pt 1), p.61-69

2003

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Potential role of peroxisome proliferator-activated receptor-α in the modulation of glucose-stimulated insulin secretion

Gender-specific programming of insulin secretion and action

Regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation

Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs

Early growth retardation induced by excessive exposure to glucocorticoids in utero selectively increases cardiac GLUT1 protein expression and Akt/protein kinase B activity in adulthood

Targeted upregulation of pyruvate dehydrogenase kinase (PDK)-4 in slow-twitch skeletal muscle underlies the stable modification of the regulatory characteristics of PDK induced by high-fat feeding

Acute (24 h) activation of peroxisome proliferator-activated receptor-alpha (PPARalpha) reverses high-fat feeding-induced insulin hypersecretion in vivo and in perifused pancreatic islets

Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin

Enhanced placental GLUT1 and GLUT3 expression in dexamethasone-induced fetal growth retardation

Early-life programming of susceptibility to dysregulation of glucose metabolism and the development of Type 2 diabetes mellitus

Maternal glucocorticoid treatment modulates placental leptin and leptin receptor expression and materno-fetal leptin physiology during late pregnancy, and elicits hypertension associated with hyperleptinaemia in the early-growth-retarded adult offspring

PDK4: A factor in fatness?

Investigation of potential mechanisms regulating protein expression of hepatic pyruvate dehydrogenase kinase isoforms 2 and 4 by fatty acids and thyroid hormone

Diabetogenic Impact of Long-Chain ω-3 Fatty Acids on Pancreatic β-Cell Function and the Regulation of Endogenous Glucose Production

Fibre-type specific modification of the activity and regulation of skeletal muscle pyruvate dehydrogenase kinase (PDK) by prolonged starvation and refeeding is associated with targeted regulation of PDK isoenzyme 4 expression

Selective modification of the pyruvate dehydrogenase kinase isoform profile in skeletal muscle in hyperthyroidism: implications for the regulatory impact of glucose on fatty acid oxidation

Acute ω-3 Fatty Acid Enrichment Selectively Reverses High-Saturated Fat Feeding-Induced Insulin Hypersecretion But Does Not Improve Peripheral Insulin Resistance

Up-regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) protein expression in oxidative skeletal muscle does not require the obligatory participation of peroxisome-proliferator-activated receptor alpha (PPARalpha)

Evaluation of the role of peroxisome-proliferator-activated receptor alpha in the regulation of cardiac pyruvate dehydrogenase kinase 4 protein expression in response to starvation, high-fat feeding and hyperthyroidism

Selective modification of pyruvate dehydrogenase kinase isoform expression in rat pancreatic islets elicited by starvation and activation of peroxisome proliferator-activated receptor-α implications for glucose-stimulated insulin secretion

Expression and regulation of pyruvate dehydrogenase kinase isoforms in the developing rat heart and in adulthood: role of thyroid hormone status and lipid supply

Interactive influences of peroxisome proliferator-activated receptor alpha activation and glucocorticoids on pancreatic beta cell compensation in insulin resistance induced by dietary saturated fat in the rat

Role of Peroxisome Proliferator-Activated Receptor-α in the Mechanism Underlying Changes in Renal Pyruvate Dehydrogenase Kinase Isoform 4 Protein Expression in Starvation and after Refeeding

Current concepts concerning the role of leptin in reproductive function

Effects of prenatal glucocorticoid exposure on cardiac calreticulin and calsequestrin protein expression during early development and in adulthood

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