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De novo evolved gene product NCYM in the pathogenesis and clinical outcome of human neuroblastomas and other cancers

Japanese journal of clinical oncology, 2020-08, Vol.50 (8), p.839-846

2020

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DNA Ligase 4 Contributes to Cell Proliferation against DNA-PK Inhibition in MYCN -Amplified Neuroblastoma IMR32 Cells

International journal of molecular sciences, 2023-05, Vol.24 (10), p.9012

2023

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FGFR2 loss sensitizes MYCN‐amplified neuroblastoma CHP134 cells to CHK1 inhibitor–induced apoptosis

Cancer science, 2022-02, Vol.113 (2), p.587-596

2022

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Editorial: Neuroblastoma: Signal Crosstalk and Future Insight Into Clinical Trials

Frontiers in oncology, 2022-03, Vol.12, p.861963-861963

2022

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Secondary Structure of Human De Novo Evolved Gene Product NCYM Analyzed by Vacuum-Ultraviolet Circular Dichroism

Frontiers in oncology, 2021-08, Vol.11, p.688852-688852

2021

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Editorial: Molecular Mechanisms and Treatment of MYCN-Driven Tumors

Frontiers in oncology, 2021-11, Vol.11, p.803443-803443

2021

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Age-related dysfunction of p53-regulated phagocytic activity in macrophages

Biochemical and biophysical research communications, 2020-08, Vol.529 (2), p.462-466

2020

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Structural characterization of human de novo protein NCYM and its complex with a newly identified DNA aptamer using atomic force microscopy and small-angle X-ray scattering

Frontiers in oncology, 2023, Vol.13, p.1213678-1213678

2023

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NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3β resulting in the stabilization of MYCN in human neuroblastomas

PLoS genetics, 2014-01, Vol.10 (1), p.e1003996

2014

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1H, 13C and 15N backbone and side-chain resonance assignments of the human oncogenic protein NCYM

Biomolecular NMR assignments, 2024-06, Vol.18 (1), p.65-70

2024

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MicroRNA induction by copy number gain is associated with poor outcome in squamous cell carcinoma of the lung

Scientific reports, 2018-10, Vol.8 (1), p.15363-10, Article 15363

2018

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Sendai virus‐mediated expression of reprogramming factors promotes plasticity of human neuroblastoma cells

Cancer science, 2015-10, Vol.106 (10), p.1351-1361

2015

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ALK is a MYCN target gene and regulates cell migration and invasion in neuroblastoma

Scientific reports, 2013-12, Vol.3 (1), Article 3450

2013

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NLRR1 Enhances EGF-Mediated MYCN Induction in Neuroblastoma and Accelerates Tumor Growth In Vivo

Cancer research (Chicago, Ill.), 2012-09, Vol.72 (17), p.4587-4596

2012

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Inactivation of beta1 integrin induces proteasomal degradation of Myc oncoproteins

Oncotarget, 2019-08, Vol.10 (48), p.4960-4972

2019

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NCYM promotes calpain-mediated Myc-nick production in human MYCN-amplified neuroblastoma cells

Biochemical and biophysical research communications, 2015-06, Vol.461 (3), p.501-506

2015

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RUNX3 Modulates DNA Damage-mediated Phosphorylation of Tumor Suppressor p53 at Ser-15 and Acts as a Co-activator for p53

The Journal of biological chemistry, 2010-05, Vol.285 (22), p.16693-16703

2010

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Expression of TSLC1, a candidate tumor suppressor gene mapped to chromosome 11q23, is downregulated in unfavorable neuroblastoma without promoter hypermethylation

International journal of cancer, 2008-11, Vol.123 (9), p.2087-2094

2008

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DNA Ligase 4 Contributes to Cell Proliferation against DNA-PK Inhibition in IMYCN/I-Amplified Neuroblastoma IMR32 Cells

International journal of molecular sciences, 2023-05, Vol.24 (10)

2023

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TATA-binding Protein (TBP)-like Protein Is Engaged in Etoposide-induced Apoptosis through Transcriptional Activation of Human TAp63 Gene

The Journal of biological chemistry, 2009-12, Vol.284 (51), p.35433-35440

2009

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Transcriptional regulation of tumor suppressor p53 by cAMP-responsive element-binding protein/AMP-activated protein kinase complex in response to glucose deprivation

Genes to cells : devoted to molecular & cellular mechanisms, 2009-12, Vol.14 (12), p.1429-1440

2009

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NFBD1/MDC1 participates in the regulation of G2/M transition in mammalian cells

Biochemical and biophysical research communications, 2010-06, Vol.397 (2), p.157-162

2010

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Sp1-mediated transcriptional regulation of NFBD1/MDC1 plays a critical role in DNA damage response pathway

Genes to cells : devoted to molecular & cellular mechanisms, 2008-01, Vol.13 (1), p.53-66

2008

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Open reading frame dominance indicates protein‐coding potential of RNAs

EMBO reports, 2022-06, Vol.23 (6), p.e54321-n/a

2022

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Transcriptional repression of the mouse wee1 gene by TBP-related factor 2

Biochemical and biophysical research communications, 2007-01, Vol.352 (1), p.21-28

2007

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De novo evolved gene product NCYM in the pathogenesis and clinical outcome of human neuroblastomas and other cancers

DNA Ligase 4 Contributes to Cell Proliferation against DNA-PK Inhibition in MYCN -Amplified Neuroblastoma IMR32 Cells

FGFR2 loss sensitizes MYCN‐amplified neuroblastoma CHP134 cells to CHK1 inhibitor–induced apoptosis

Editorial: Neuroblastoma: Signal Crosstalk and Future Insight Into Clinical Trials

Secondary Structure of Human De Novo Evolved Gene Product NCYM Analyzed by Vacuum-Ultraviolet Circular Dichroism

Editorial: Molecular Mechanisms and Treatment of MYCN-Driven Tumors

Age-related dysfunction of p53-regulated phagocytic activity in macrophages

Structural characterization of human de novo protein NCYM and its complex with a newly identified DNA aptamer using atomic force microscopy and small-angle X-ray scattering

NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3β resulting in the stabilization of MYCN in human neuroblastomas

1H, 13C and 15N backbone and side-chain resonance assignments of the human oncogenic protein NCYM

MicroRNA induction by copy number gain is associated with poor outcome in squamous cell carcinoma of the lung

Sendai virus‐mediated expression of reprogramming factors promotes plasticity of human neuroblastoma cells

ALK is a MYCN target gene and regulates cell migration and invasion in neuroblastoma

NLRR1 Enhances EGF-Mediated MYCN Induction in Neuroblastoma and Accelerates Tumor Growth In Vivo

Inactivation of beta1 integrin induces proteasomal degradation of Myc oncoproteins

NCYM promotes calpain-mediated Myc-nick production in human MYCN-amplified neuroblastoma cells

RUNX3 Modulates DNA Damage-mediated Phosphorylation of Tumor Suppressor p53 at Ser-15 and Acts as a Co-activator for p53

Expression of TSLC1, a candidate tumor suppressor gene mapped to chromosome 11q23, is downregulated in unfavorable neuroblastoma without promoter hypermethylation

DNA Ligase 4 Contributes to Cell Proliferation against DNA-PK Inhibition in IMYCN/I-Amplified Neuroblastoma IMR32 Cells

TATA-binding Protein (TBP)-like Protein Is Engaged in Etoposide-induced Apoptosis through Transcriptional Activation of Human TAp63 Gene

Transcriptional regulation of tumor suppressor p53 by cAMP-responsive element-binding protein/AMP-activated protein kinase complex in response to glucose deprivation

NFBD1/MDC1 participates in the regulation of G2/M transition in mammalian cells

Sp1-mediated transcriptional regulation of NFBD1/MDC1 plays a critical role in DNA damage response pathway

Open reading frame dominance indicates protein‐coding potential of RNAs

Transcriptional repression of the mouse wee1 gene by TBP-related factor 2

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