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Chiral pyrrolidines as multipotent agents in Alzheimer and neurodegenerative diseases
Bioorganic & medicinal chemistry, 2024-08, Vol.110, p.117829, Article 117829
2024
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The Phenoxyalkyltriazine Antagonists for 5-HT6 Receptor with Promising Procognitive and Pharmacokinetic Properties In Vivo in Search for a Novel Therapeutic Approach to Dementia Diseases
International journal of molecular sciences, 2021-10, Vol.22 (19), p.10773
2021
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First-in-Class Selenium-Containing Potent Serotonin Receptor 5‑HT6 Agents with a Beneficial Neuroprotective Profile against Alzheimer’s Disease
Journal of medicinal chemistry, 2024-01, Vol.67 (2), p.1580-1610
2024
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Synthesis, computational and experimental pharmacological studies for (thio)ether-triazine 5-HT6R ligands with noticeable action on AChE/BChE and chalcogen-dependent intrinsic activity in search for new class of drugs against Alzheimer's disease
European journal of medicinal chemistry, 2023-11, Vol.259, p.115695-115695, Article 115695
2023
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Hydrophobicity modulation via the substituents at positions 2 and 4 of 1,3,5-triazine to enhance therapeutic ability against Alzheimer's disease for potent serotonin 5-HT6R agents
European journal of medicinal chemistry, 2023-11, Vol.260, p.115756-115756, Article 115756
2023
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Rational design of new multitarget histamine H 3 receptor ligands as potential candidates for treatment of Alzheimer's disease
European journal of medicinal chemistry, 2020-12, Vol.207, p.112743
2020
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Chlorine substituents and linker topology as factors of 5-HT6R activity for novel highly active 1,3,5-triazine derivatives with procognitive properties in vivo
European journal of medicinal chemistry, 2020-10, Vol.203, p.112529, Article 112529
2020
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Synthesis and computer-aided SAR studies for derivatives of phenoxyalkyl-1,3,5-triazine as the new potent ligands for serotonin receptors 5-HT6
European journal of medicinal chemistry, 2019-09, Vol.178, p.740-751
2019
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An exit beyond the pharmacophore model for 5-HT6R agents - a new strategy to gain dual 5-HT6/5-HT2A action for triazine derivatives with procognitive potential
Bioorganic chemistry, 2022-04, Vol.121, p.105695-105695, Article 105695
2022
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Benzophenone Derivatives with Histamine H 3 Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease
Molecules (Basel, Switzerland), 2023-01, Vol.28 (1)
2023
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Histamine H3 Receptor Ligands—KSK-59 and KSK-73—Reduce Body Weight Gain in a Rat Model of Excessive Eating
Pharmaceuticals (Basel, Switzerland), 2021-10, Vol.14 (11), p.1080
2021
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THE EFFECT OF THE CUTTING METHOD ON ROOTING OF Dahlia pinnata Cav. CUTTINGS
Acta scientiarum Polonorum. Hortorum cultus (Ogrodnictwo), 2017-01, Vol.16 (2)
2017
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Benzophenone Derivatives with Histamine H3 Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer’s Disease
Molecules (Basel, Switzerland), 2022-12, Vol.28 (1), p.238
2022
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THE EFFICIENCY OF MOTHER CROWNS AND QUALITY OF SOFT CUTTINGS OF A FEW DAHLIA CULTIVARS
Acta scientiarum Polonorum. Hortorum cultus (Ogrodnictwo), 2015-01, Vol.14 (6)
2015
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Assessment of therapeutic education conducted by nurses in patients with type 2 diabetes in the context of the sense of coherence
Pielęgniarstwo XXI Wieku, 2017-12, Vol.16 (4), p.9-16
2017
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Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of Alzheimer’s disease
European journal of medicinal chemistry, 2020-12, Vol.207, p.112743, Article 112743
2020
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Abstract 1281: Development and characterization of small molecule HPK1 inhibitors
Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1281-1281
2021
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Abstract 4532A: Development of selective small molecule STING agonists suitable for systemic administration
Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.4532-4532A
2020
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Abstract 1947: Development and characterization of small molecule HPK1 inhibitors
Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.1947-1947
2020
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Abstract 4983: Discovery and characterization of next-generation small molecule direct STING agonists
Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.4983-4983
2019
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Chlorine substituents and linker topology as factors of 5-HT 6 R activity for novel highly active 1,3,5-triazine derivatives with procognitive properties in vivo
European journal of medicinal chemistry, 2020-10, Vol.203, p.112529
2020
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First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT 6 Agents with a Beneficial Neuroprotective Profile against Alzheimer's Disease
Journal of medicinal chemistry, 2024-01, Vol.67 (2), p.1580-1610
2024
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Benzophenone Derivatives with Histamine H[sub.3] Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer’s Disease
Molecules (Basel, Switzerland), 2022-12, Vol.28 (1)
2022
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Synthesis and computer-aided SAR studies for derivatives of phenoxyalkyl-1,3,5-triazine as the new potent ligands for serotonin receptors 5-HT 6
European journal of medicinal chemistry, 2019-06, Vol.178, p.740
2019
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Synthesis, computational and experimental pharmacological studies for (thio)ether-triazine 5-HT 6 R ligands with noticeable action on AChE/BChE and chalcogen-dependent intrinsic activity in search for new class of drugs against Alzheimer's disease
European journal of medicinal chemistry, 2023-07, Vol.259, p.115695
2023
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