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Big Lessons from Tiny Flies: Drosophila melanogaster as a Model to Explore Dysfunction of Dopaminergic and Serotonergic Neurotransmitter Systems

International journal of molecular sciences, 2018-06, Vol.19 (6), p.1788

2018

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A mechanism of uncompetitive inhibition of the serotonin transporter

eLife, 2023-01, Vol.12

2023

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The Creatine Transporter Unfolded: A Knotty Premise in the Cerebral Creatine Deficiency Syndrome

Frontiers in synaptic neuroscience, 2020-10, Vol.12, p.588954-588954

2020

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STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behavior

Scientific reports, 2015-03, Vol.5 (1), p.9009-9009, Article 9009

2015

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A transporter's doom or destiny: SLC6A1 in health and disease, novel molecular targets and emerging therapeutic prospects

Frontiers in molecular neuroscience, 2024-08, Vol.17, p.1466694

2024

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Cooperative Binding of Substrate and Ions Drives Forward Cycling of the Human Creatine Transporter-1

Frontiers in physiology, 2022-06, Vol.13, p.919439-919439

2022

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Molecular and Clinical Repercussions of GABA Transporter 1 Variants Gone Amiss: Links to Epilepsy and Developmental Spectrum Disorders

Frontiers in molecular biosciences, 2022-03, Vol.9, p.834498-834498

2022

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The Serotonin Transporter Is an Exclusive Client of the Coat Protein Complex II (COPII) Component SEC24C

The Journal of biological chemistry, 2011-05, Vol.286 (18), p.16482-16490

2011

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Drosophila melanogaster as a model for unraveling unique molecular features of epilepsy elicited by human GABA transporter 1 variants

Frontiers in neuroscience, 2023-01, Vol.16, p.1074427-1074427

2023

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The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter

Molecular pharmacology, 2010-12, Vol.78 (6), p.1026-1035

2010

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The N Terminus of Monoamine Transporters Is a Lever Required for the Action of Amphetamines

The Journal of biological chemistry, 2010-04, Vol.285 (14), p.10924-10938

2010

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Constitutive Endocytosis of the Neuronal Glutamate Transporter Excitatory Amino Acid Transporter-3 Requires ARFGAP1

Frontiers in physiology, 2021-05, Vol.12, p.671034-671034

2021

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Rescue of Misfolded Organic Cation Transporter 3 Variants

Cells (Basel, Switzerland), 2022-12, Vol.12 (1), p.39

2022

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Relax, Cool Down and Scaffold: How to Restore Surface Expression of Folding-Deficient Mutant GPCRs and SLC6 Transporters

International journal of molecular sciences, 2017-11, Vol.18 (11), p.2416

2017

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Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits

Pharmacology & therapeutics (Oxford), 2021-06, Vol.222, p.107785-107785, Article 107785

2021

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First Trimester Pregnancy Decidual Natural Killer Cells Contain and Spontaneously Release High Quantities of Granulysin

American journal of reproductive immunology (1989), 2011-11, Vol.66 (5), p.363-372

2011

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4‐Phenylbutyrate rescues folding‐deficient creatine transporter‐1 variants linked to the creatine transporter deficiency syndrome

The FASEB journal, 2019-04, Vol.33 (S1), p.780.12-780.12

2019

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An unfolding story: Small molecules remedy misfolded monoamine transporters

The international journal of biochemistry & cell biology, 2017-11, Vol.92, p.1-5

2017

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Distinct contribution of axonal and somatodendritic serotonin transporters in drosophila olfaction

Neuropharmacology, 2019-12, Vol.161, p.107564-107564, Article 107564

2019

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Breaking the rules of SLC6 transporters: Export of the human creatine transporter‐1 from the endoplasmic reticulum is supported by its N‐terminus

Journal of neurochemistry, 2024-09, Vol.168 (9), p.2007-2021

2024

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Rescue by 4-phenylbutyrate of several misfolded creatine transporter-1 variants linked to the creatine transporter deficiency syndrome

Neuropharmacology, 2019-12, Vol.161, p.107572-107572, Article 107572

2019

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Corrigendum to “Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits” [Pharmacology & Therapeutics 222 (2021) 107785]

Pharmacology & therapeutics (Oxford), 2021-09, Vol.225, p.107816-107816, Article 107816

2021

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SLC6 Transporter Folding Diseases and Pharmacochaperoning

Handbook of experimental pharmacology, 2018, Vol.245, p.249-270

2018

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Comparison of the β-Adrenergic Receptor Antagonists Landiolol and Esmolol: Receptor Selectivity, Partial Agonism, and Pharmacochaperoning Actions

The Journal of pharmacology and experimental therapeutics, 2016-10, Vol.359 (1), p.73

2016

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Probing binding and occlusion of substrate in the human creatine transporter‐1 by computation and mutagenesis

Protein science, 2024-01, Vol.33 (1), p.e4842-n/a

2024

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Big Lessons from Tiny Flies: Drosophila melanogaster as a Model to Explore Dysfunction of Dopaminergic and Serotonergic Neurotransmitter Systems

A mechanism of uncompetitive inhibition of the serotonin transporter

The Creatine Transporter Unfolded: A Knotty Premise in the Cerebral Creatine Deficiency Syndrome

STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behavior

A transporter's doom or destiny: SLC6A1 in health and disease, novel molecular targets and emerging therapeutic prospects

Cooperative Binding of Substrate and Ions Drives Forward Cycling of the Human Creatine Transporter-1

Molecular and Clinical Repercussions of GABA Transporter 1 Variants Gone Amiss: Links to Epilepsy and Developmental Spectrum Disorders

The Serotonin Transporter Is an Exclusive Client of the Coat Protein Complex II (COPII) Component SEC24C

Drosophila melanogaster as a model for unraveling unique molecular features of epilepsy elicited by human GABA transporter 1 variants

The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter

The N Terminus of Monoamine Transporters Is a Lever Required for the Action of Amphetamines

Constitutive Endocytosis of the Neuronal Glutamate Transporter Excitatory Amino Acid Transporter-3 Requires ARFGAP1

Rescue of Misfolded Organic Cation Transporter 3 Variants

Relax, Cool Down and Scaffold: How to Restore Surface Expression of Folding-Deficient Mutant GPCRs and SLC6 Transporters

Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits

First Trimester Pregnancy Decidual Natural Killer Cells Contain and Spontaneously Release High Quantities of Granulysin

4‐Phenylbutyrate rescues folding‐deficient creatine transporter‐1 variants linked to the creatine transporter deficiency syndrome

An unfolding story: Small molecules remedy misfolded monoamine transporters

Distinct contribution of axonal and somatodendritic serotonin transporters in drosophila olfaction

Breaking the rules of SLC6 transporters: Export of the human creatine transporter‐1 from the endoplasmic reticulum is supported by its N‐terminus

Rescue by 4-phenylbutyrate of several misfolded creatine transporter-1 variants linked to the creatine transporter deficiency syndrome

Corrigendum to “Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits” [Pharmacology & Therapeutics 222 (2021) 107785]

SLC6 Transporter Folding Diseases and Pharmacochaperoning

Comparison of the β-Adrenergic Receptor Antagonists Landiolol and Esmolol: Receptor Selectivity, Partial Agonism, and Pharmacochaperoning Actions

Probing binding and occlusion of substrate in the human creatine transporter‐1 by computation and mutagenesis

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