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G6PC mRNA Therapy Positively Regulates Fasting Blood Glucose and Decreases Liver Abnormalities in a Mouse Model of Glycogen Storage Disease 1a

Molecular therapy, 2018-03, Vol.26 (3), p.814-821

2018

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Optimization of mRNA untranslated regions for improved expression of therapeutic mRNA

RNA biology, 2018-03, Vol.15 (6), p.756-762

2018

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mRNA treatment produces sustained expression of enzymatically active human ADAMTS13 in mice

Scientific reports, 2018-05, Vol.8 (1), p.7859-9, Article 7859

2018

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siRNA off-target effects can be reduced at concentrations that match their individual potency

PloS one, 2011-07, Vol.6 (7), p.e21503-e21503

2011

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Arginase I mRNA therapy - a novel approach to rescue arginase 1 enzyme deficiency

RNA biology, 2018-07, Vol.15 (7), p.914-922

2018

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SERPINA1 mRNA as a Treatment for Alpha-1 Antitrypsin Deficiency

Journal of nucleic acids, 2018-01, Vol.2018 (2018), p.1-7

2018

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14-3-3 proteins: structure, function, and regulation

Annual review of pharmacology and toxicology, 2000-01, Vol.40 (1), p.617-647

2000

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Combination therapy targeting Raf-1 and MEK causes apoptosis of HCT116 colon cancer cells

International journal of oncology, 2012-11, Vol.41 (5), p.1855-1862

2012

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Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase

Cancer cell, 2003-05, Vol.3 (5), p.483-495

2003

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Enhancing antisense efficacy with multimers and multi-targeting oligonucleotides (MTOs) using cleavable linkers

Nucleic acids research, 2015-10, Vol.43 (19), p.9123-9132

2015

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Systemic Alanine Glyoxylate Aminotransferase mRNA Improves Glyoxylate Metabolism in a Mouse Model of Primary Hyperoxaluria Type 1

Nucleic acid therapeutics, 2019-04, Vol.29 (2), p.104-113

2019

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Uptake, Efficacy, and Systemic Distribution of Naked, Inhaled Short Interfering RNA (siRNA) and Locked Nucleic Acid (LNA) Antisense

Molecular therapy, 2011-12, Vol.19 (12), p.2163-2168

2011

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Leveraging Rational Protein Engineering to Improve mRNA Therapeutics

Nucleic acid therapeutics, 2018-04, Vol.28 (2), p.74-85

2018

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Potential Role of Axonal Chemorepellent Slit2 in Modulating Adventitial Inflammation in a Rat Carotid Artery Balloon Injury Model

Journal of cardiovascular pharmacology, 2016-05, Vol.67 (5), p.433-441

2016

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Expression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vessels

Arteriosclerosis, thrombosis, and vascular biology, 1997-11, Vol.17 (11), p.2479-2488

1997

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Development of a sensitive ELISA to quantify apolipoprotein CIII in nonhuman primate serum

Journal of lipid research, 2011-06, Vol.52 (6), p.1265-1271

2011

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14-3-3η Amplifies Androgen Receptor Actions in Prostate Cancer

Clinical cancer research, 2009-12, Vol.15 (24), p.7571-7581

2009

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DEF-1/ASAP1 Is a GTPase-activating Protein (GAP) for ARF1 That Enhances Cell Motility through a GAP-dependent Mechanism

The Journal of biological chemistry, 2002-03, Vol.277 (10), p.7962-7969

2002

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Protein phosphatase 2A activates the proapoptotic function of BAD in interleukin- 3–dependent lymphoid cells by a mechanism requiring 14-3-3 dissociation

Blood, 2001-03, Vol.97 (5), p.1289-1297

2001

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Interaction of apoptosis signal-regulating kinase 1 with isoforms of 14-3-3 proteins

Experimental cell research, 2004-04, Vol.294 (2), p.581-591

2004

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Enhanced exon skipping and prolonged dystrophin restoration achieved by TfR1-targeted delivery of antisense oligonucleotide using FORCE conjugation in mdx mice

Nucleic acids research, 2022-11, Vol.50 (20), p.11401-11414

2022

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miRNA Alterations Modify Kinase Activation In The IGF-1 Pathway And Correlate With Colorectal Cancer Stage And Progression In Patients

Journal of Cancer, 2011-01, Vol.2 (1), p.490-502

2011

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Dietary correction of hypercholesterolemia in the rabbit normalizes endothelial superoxide anion production

Circulation (New York, N.Y.), 1995-08, Vol.92 (4), p.898-903

1995

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Functional Conservation of 14-3-3 Isoforms in Inhibiting Bad-Induced Apoptosis

Experimental cell research, 2001-11, Vol.271 (1), p.142-151

2001

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14-3-3{eta} Amplifies Androgen Receptor Actions in Prostate Cancer

Clinical cancer research, 2009-12, Vol.15 (24), p.7571-7581

2009

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G6PC mRNA Therapy Positively Regulates Fasting Blood Glucose and Decreases Liver Abnormalities in a Mouse Model of Glycogen Storage Disease 1a

Optimization of mRNA untranslated regions for improved expression of therapeutic mRNA

mRNA treatment produces sustained expression of enzymatically active human ADAMTS13 in mice

siRNA off-target effects can be reduced at concentrations that match their individual potency

Arginase I mRNA therapy - a novel approach to rescue arginase 1 enzyme deficiency

SERPINA1 mRNA as a Treatment for Alpha-1 Antitrypsin Deficiency

14-3-3 proteins: structure, function, and regulation

Combination therapy targeting Raf-1 and MEK causes apoptosis of HCT116 colon cancer cells

Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase

Enhancing antisense efficacy with multimers and multi-targeting oligonucleotides (MTOs) using cleavable linkers

Systemic Alanine Glyoxylate Aminotransferase mRNA Improves Glyoxylate Metabolism in a Mouse Model of Primary Hyperoxaluria Type 1

Uptake, Efficacy, and Systemic Distribution of Naked, Inhaled Short Interfering RNA (siRNA) and Locked Nucleic Acid (LNA) Antisense

Leveraging Rational Protein Engineering to Improve mRNA Therapeutics

Potential Role of Axonal Chemorepellent Slit2 in Modulating Adventitial Inflammation in a Rat Carotid Artery Balloon Injury Model

Expression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vessels

Development of a sensitive ELISA to quantify apolipoprotein CIII in nonhuman primate serum

14-3-3η Amplifies Androgen Receptor Actions in Prostate Cancer

DEF-1/ASAP1 Is a GTPase-activating Protein (GAP) for ARF1 That Enhances Cell Motility through a GAP-dependent Mechanism

Protein phosphatase 2A activates the proapoptotic function of BAD in interleukin- 3–dependent lymphoid cells by a mechanism requiring 14-3-3 dissociation

Interaction of apoptosis signal-regulating kinase 1 with isoforms of 14-3-3 proteins

Enhanced exon skipping and prolonged dystrophin restoration achieved by TfR1-targeted delivery of antisense oligonucleotide using FORCE conjugation in mdx mice

miRNA Alterations Modify Kinase Activation In The IGF-1 Pathway And Correlate With Colorectal Cancer Stage And Progression In Patients

Dietary correction of hypercholesterolemia in the rabbit normalizes endothelial superoxide anion production

Functional Conservation of 14-3-3 Isoforms in Inhibiting Bad-Induced Apoptosis

14-3-3{eta} Amplifies Androgen Receptor Actions in Prostate Cancer

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