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Cytokines and Their Roles in Pancreatic Islet β-Cell Destruction and Insulin-Dependent Diabetes Mellitus

Biochemical pharmacology, 1998-04, Vol.55 (8), p.1139-1149

1998

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Combination therapy with a dipeptidyl peptidase-4 inhibitor and a proton pump inhibitor restores normoglycaemia in non-obese diabetic mice

Diabetologia, 2009-08, Vol.52 (8), p.1680-1682

2009

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Th1 to Th2 Cytokine Shifts in Nonobese Diabetic Mice: Sometimes an Outcome, Rather Than the Cause, of Diabetes Resistance Elicited by Immunostimulation

The Journal of immunology (1950), 2001-01, Vol.166 (2), p.1352-1359

2001

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Combination therapy with low dose sirolimus and tacrolimus is synergistic in preventing spontaneous and recurrent autoimmune diabetes in non-obese diabetic mice

Diabetologia, 2002-02, Vol.45 (2), p.224-230

2002

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Testicular Sertoli cells exert both protective and destructive effects on syngeneic islet grafts in non-obese diabetic mice

Diabetologia, 2000-04, Vol.43 (4), p.474-480

2000

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Fas ligand-mediated mechanisms are involved in autoimmune destruction of islet beta cells in non-obese diabetic mice

Diabetologia, 2000-09, Vol.43 (9), p.1149-1156

2000

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Combination Therapy With Epidermal Growth Factor and Gastrin Delays Autoimmune Diabetes Recurrence in Nonobese Diabetic Mice Transplanted With Syngeneic Islets

Transplantation proceedings, 2008-03, Vol.40 (2), p.529-532

2008

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Imbalance between tissue inhibitor of metalloproteinase-4 and matrix metalloproteinases during acute myocardial ischemia-reperfusion injury

Circulation (New York, N.Y.), 2003-05, Vol.107 (19), p.2487-2492

2003

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Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet beta-cells

Diabetes (New York, N.Y.), 1997-05, Vol.46 (5), p.907-911

1997

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DNA fragmentation is an early event in cytokine-induced islet beta-cell destruction

Diabetologia, 1994-08, Vol.37 (8), p.733-738

1994

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Human pancreatic islet β-cell destruction by cytokines involves oxygen free radicals and aldehyde production

The journal of clinical endocrinology and metabolism, 1996-09, Vol.81 (9), p.3197-3202

1996

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Inhibition of poly (ADP‐ribose) synthetase by gene disruption or inhibition with 5‐iodo‐6‐amino‐1,2‐benzopyrone protects mice from multiple‐low‐dose‐streptozotocin‐induced diabetes

British journal of pharmacology, 2001-07, Vol.133 (6), p.909-919

2001

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TNF-alpha down-regulates type 1 cytokines and prolongs survival of syngeneic islet grafts in nonobese diabetic mice

The Journal of immunology (1950), 1997-12, Vol.159 (12), p.6298-6303

1997

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An Inhibitor of Inducible Nitric Oxide Synthase and Scavenger of Peroxynitrite Prevents Diabetes Development in NOD Mice

Journal of autoimmunity, 2001-06, Vol.16 (4), p.449-455

2001

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Inducible nitric oxide synthase (iNOS) in pancreatic islets of nonobese diabetic mice: identification of iNOS- expressing cells and relationships to cytokines expressed in the islets

Endocrinology (Philadelphia), 1996-05, Vol.137 (5), p.2093-2099

1996

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Peroxynitrite Is a Mediator of Cytokine-Induced Destruction of Human Pancreatic Islet β Cells

Laboratory investigation, 2001-12, Vol.81 (12), p.1683-1692

2001

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Neonatal Porcine Islet Xenografts in Nonobese Diabetic Mice: Effects on Blood Glucose and Analysis of Cytokines Expressed in the Islet Grafts

Transplantation proceedings, 1998-03, Vol.30 (2), p.654-655

1998

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Prolongation of Allograft Survival of Transfected Islets Expressing Human CTLA4-Ig, Human Soluble Fas Ligand or a Combination of the Two

Transplantation proceedings, 1998-03, Vol.30 (2), p.534-534

1998

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IFN-gamma gene expression in pancreatic islet-infiltrating mononuclear cells correlates with autoimmune diabetes in nonobese diabetic mice

The Journal of immunology (1950), 1995-05, Vol.154 (9), p.4874-4882

1995

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Both CD4+and CD8+T cells are Required for IFN-γ Gene Expression in Pancreatic Islets and Autoimmune Diabetes Development in Biobreeding Rats

Journal of autoimmunity, 1999-03, Vol.12 (2), p.109-119

1999

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Intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury

Circulation (New York, N.Y.), 2002-09, Vol.106 (12), p.1543-1549

2002

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Combination Therapy with Epidermal Growth Factor and Gastrin Induces Neogenesis of Human Islet β-Cells from Pancreatic Duct Cells and an Increase in Functional β-Cell Mass

The journal of clinical endocrinology and metabolism, 2005-06, Vol.90 (6), p.3401-3409

2005

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Improved survival of biolistically transfected mouse islet allografts expressing CTLA4-Ig or soluble Fas ligand

Transplantation, 1998-07, Vol.66 (2), p.194

1998

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Combination Therapy With Epidermal Growth Factor and Gastrin Increases β-Cell Mass and Reverses Hyperglycemia in Diabetic NOD Mice

Diabetes (New York, N.Y.), 2005-09, Vol.54 (9), p.2596-2601

2005

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Destruction of rat pancreatic islet beta-cells by cytokines involves the production of cytotoxic aldehydes

Endocrinology (Philadelphia), 1996-12, Vol.137 (12), p.5290-5296

1996

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Cytokines and Their Roles in Pancreatic Islet β-Cell Destruction and Insulin-Dependent Diabetes Mellitus

Combination therapy with a dipeptidyl peptidase-4 inhibitor and a proton pump inhibitor restores normoglycaemia in non-obese diabetic mice

Th1 to Th2 Cytokine Shifts in Nonobese Diabetic Mice: Sometimes an Outcome, Rather Than the Cause, of Diabetes Resistance Elicited by Immunostimulation

Combination therapy with low dose sirolimus and tacrolimus is synergistic in preventing spontaneous and recurrent autoimmune diabetes in non-obese diabetic mice

Testicular Sertoli cells exert both protective and destructive effects on syngeneic islet grafts in non-obese diabetic mice

Fas ligand-mediated mechanisms are involved in autoimmune destruction of islet beta cells in non-obese diabetic mice

Combination Therapy With Epidermal Growth Factor and Gastrin Delays Autoimmune Diabetes Recurrence in Nonobese Diabetic Mice Transplanted With Syngeneic Islets

Imbalance between tissue inhibitor of metalloproteinase-4 and matrix metalloproteinases during acute myocardial ischemia-reperfusion injury

Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet beta-cells

DNA fragmentation is an early event in cytokine-induced islet beta-cell destruction

Human pancreatic islet β-cell destruction by cytokines involves oxygen free radicals and aldehyde production

Inhibition of poly (ADP‐ribose) synthetase by gene disruption or inhibition with 5‐iodo‐6‐amino‐1,2‐benzopyrone protects mice from multiple‐low‐dose‐streptozotocin‐induced diabetes

TNF-alpha down-regulates type 1 cytokines and prolongs survival of syngeneic islet grafts in nonobese diabetic mice

An Inhibitor of Inducible Nitric Oxide Synthase and Scavenger of Peroxynitrite Prevents Diabetes Development in NOD Mice

Inducible nitric oxide synthase (iNOS) in pancreatic islets of nonobese diabetic mice: identification of iNOS- expressing cells and relationships to cytokines expressed in the islets

Peroxynitrite Is a Mediator of Cytokine-Induced Destruction of Human Pancreatic Islet β Cells

Neonatal Porcine Islet Xenografts in Nonobese Diabetic Mice: Effects on Blood Glucose and Analysis of Cytokines Expressed in the Islet Grafts

Prolongation of Allograft Survival of Transfected Islets Expressing Human CTLA4-Ig, Human Soluble Fas Ligand or a Combination of the Two

IFN-gamma gene expression in pancreatic islet-infiltrating mononuclear cells correlates with autoimmune diabetes in nonobese diabetic mice

Both CD4+and CD8+T cells are Required for IFN-γ Gene Expression in Pancreatic Islets and Autoimmune Diabetes Development in Biobreeding Rats

Intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury

Combination Therapy with Epidermal Growth Factor and Gastrin Induces Neogenesis of Human Islet β-Cells from Pancreatic Duct Cells and an Increase in Functional β-Cell Mass

Improved survival of biolistically transfected mouse islet allografts expressing CTLA4-Ig or soluble Fas ligand

Combination Therapy With Epidermal Growth Factor and Gastrin Increases β-Cell Mass and Reverses Hyperglycemia in Diabetic NOD Mice

Destruction of rat pancreatic islet beta-cells by cytokines involves the production of cytotoxic aldehydes

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