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Preferential inhibition of T helper 1, but not T helper 2, cytokines in vitro by L-826,141 [4-[2-(3,4-Bisdifluromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]3-methylpyridine-1-oxide], a potent and selective phosphodiesterase 4 inhibitor

The Journal of pharmacology and experimental therapeutics, 2004-08, Vol.310 (2), p.752-760

2004

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Peripheral phosphodiesterase 4 inhibition produced by 4-[2-(3,4-Bis-difluoromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]-3-methylpyridine-1-oxide (L-826,141) prevents experimental autoimmune encephalomyelitis

The Journal of pharmacology and experimental therapeutics, 2006-10, Vol.319 (1), p.63-72

2006

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L-454,560, a potent and selective PDE4 inhibitor with in vivo efficacy in animal models of asthma and cognition

Biochemical pharmacology, 2007-06, Vol.73 (12), p.1971-1981

2007

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Optimization of a Tertiary Alcohol Series of Phosphodiesterase-4 (PDE4) Inhibitors: Structure−Activity Relationship Related to PDE4 Inhibition and Human Ether-a-go-go Related Gene Potassium Channel Binding Affinity

Journal of medicinal chemistry, 2003-06, Vol.46 (12), p.2413-2426

2003

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The effects of phosphodiesterase type 4 inhibitors on tumour necrosis factor‐ α and leukotriene B 4 in a novel human whole blood assay

British journal of pharmacology, 2009-01, Vol.126 (4), p.979-988

2009

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Synthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid by human monocytes and lymphocytes

Journal of leukocyte biology, 1996-06, Vol.59 (6), p.847-854

1996

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Antiproliferative effect of prostaglandin E2 in cultured guinea pig tracheal smooth muscle cells

American journal of physiology. Lung cellular and molecular physiology, 1994-02, Vol.266 (2), p.131-L137

1994

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The effects of phosphodiesterase type 4 inhibitors on tumour necrosis factor‐α and leukotriene B4 in a novel human whole blood assay

British journal of pharmacology, 1999-02, Vol.126 (4), p.979-988

1999

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Evaluation of loxoprofen and its alcohol metabolites for potency and selectivity of inhibition of cyclooxygenase-2

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (5), p.1201-1203

2004

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In vitro metabolism considerations, including activity testing of metabolites, in the discovery and selection of the COX-2 inhibitor etoricoxib (MK-0663)

Bioorganic & medicinal chemistry letters, 2001-04, Vol.11 (8), p.1059-1062

2001

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Nitrogen-bridged substituted 8-arylquinolines as potent PDE IV inhibitors

Bioorganic & medicinal chemistry letters, 2006-05, Vol.16 (10), p.2608-2612

2006

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L-454,560, a potent and selective PDE4 inhibitor with in uiuo efficacy in animal models of asthma and cognition

Biochemical pharmacology, 2007, Vol.73 (12), p.1971-1981

2007

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Substituted 2-Pyridinemethanol derivatives as potent and selective phosphodiesterase-4 inhibitors

Bioorganic & medicinal chemistry letters, 2003-06, Vol.13 (11), p.1923-1926

2003

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Substituted aminopyridines as potent and selective phosphodiesterase-4 inhibitors

Bioorganic & medicinal chemistry letters, 2003-02, Vol.13 (4), p.741-744

2003

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Mechanical Responses of Tracheal Tissue In Vitro: Dependance on the Tissue Preparation Employed and Relationship to Smooth Muscle Content

Pulmonary pharmacology (Edinburgh), 1996-06, Vol.9 (3), p.157-166

1996

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Increased maximal pulmonary response to methacholine and airway smooth muscle in immature compared with mature rabbits

American journal of respiratory and critical care medicine, 1995-03, Vol.151 (3 Pt 1), p.836-840

1995

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Antioproliferative effect of prostaglandin E2 in cultured guinea pig tracheal smooth muscle cells

American journal of physiology. Lung cellular and molecular physiology, 1994, Vol.10 (2), p.L131-L137

1994

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Mechanical responses of tracheal tissue in vitro: dependence on the tissue preparation employed and relationship to smooth muscle content

Pulmonary pharmacology (Edinburgh), 1996-06, Vol.9 (3), p.157-166

1996

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AUTOMATED RECONSTRUCTION OF HISTORIC ROOF STRUCTURES FROM POINT CLOUDS – DEVELOPMENT AND EXAMPLES

ISPRS annals of the photogrammetry, remote sensing and spatial information sciences, 2017-08, Vol.IV-2/W2, p.195-202

2017

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vasa is required for GURKEN accumulation in the oocyte, and is involved in oocyte differentiation and germline cyst development

Development (Cambridge), 1998-05, Vol.125 (9), p.1569-1578

1998

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Concurrent validity and reliability of measuring range of motion during the cervical flexion rotation test with a novel digital goniometer

BMC musculoskeletal disorders, 2020-08, Vol.21 (1), p.535-535, Article 535

2020

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Development of a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor (MK-8245) to Establish a Therapeutic Window for the Treatment of Diabetes and Dyslipidemia

Journal of medicinal chemistry, 2011-07, Vol.54 (14), p.5082-5096

2011

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Correction to: Concurrent validity and reliability of measuring range of motion during the cervical flexion rotation test with a novel digital goniometer

BMC musculoskeletal disorders, 2020-09, Vol.21 (1), p.1-624, Article 624

2020

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DIGITAL WORKFLOWS FOR RESTORATION AND MANAGEMENT OF THE MUSEUM AFFANDI - A CASE STUDY IN CHALLENGING CIRCUMSTANCES

International archives of the photogrammetry, remote sensing and spatial information sciences., 2017, Vol.XLII-2/W5, p.329-334

2017

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Preferential inhibition of T helper 1, but not T helper 2, cytokines in vitro by L-826,141 [4-[2-(3,4-Bisdifluromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]3-methylpyridine-1-oxide], a potent and selective phosphodiesterase 4 inhibitor

Peripheral phosphodiesterase 4 inhibition produced by 4-[2-(3,4-Bis-difluoromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]-3-methylpyridine-1-oxide (L-826,141) prevents experimental autoimmune encephalomyelitis

L-454,560, a potent and selective PDE4 inhibitor with in vivo efficacy in animal models of asthma and cognition

Optimization of a Tertiary Alcohol Series of Phosphodiesterase-4 (PDE4) Inhibitors: Structure−Activity Relationship Related to PDE4 Inhibition and Human Ether-a-go-go Related Gene Potassium Channel Binding Affinity

The effects of phosphodiesterase type 4 inhibitors on tumour necrosis factor‐ α and leukotriene B 4 in a novel human whole blood assay

Synthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid by human monocytes and lymphocytes

Antiproliferative effect of prostaglandin E2 in cultured guinea pig tracheal smooth muscle cells

The effects of phosphodiesterase type 4 inhibitors on tumour necrosis factor‐α and leukotriene B4 in a novel human whole blood assay

Discovery of a substituted 8-arylquinoline series of PDE4 inhibitors: Structure–activity relationship, optimization, and identification of a highly potent, well tolerated, PDE4 inhibitor

Evaluation of loxoprofen and its alcohol metabolites for potency and selectivity of inhibition of cyclooxygenase-2

In vitro metabolism considerations, including activity testing of metabolites, in the discovery and selection of the COX-2 inhibitor etoricoxib (MK-0663)

Nitrogen-bridged substituted 8-arylquinolines as potent PDE IV inhibitors

L-454,560, a potent and selective PDE4 inhibitor with in uiuo efficacy in animal models of asthma and cognition

Substituted 2-Pyridinemethanol derivatives as potent and selective phosphodiesterase-4 inhibitors

Substituted aminopyridines as potent and selective phosphodiesterase-4 inhibitors

Mechanical Responses of Tracheal Tissue In Vitro: Dependance on the Tissue Preparation Employed and Relationship to Smooth Muscle Content

Increased maximal pulmonary response to methacholine and airway smooth muscle in immature compared with mature rabbits

Antioproliferative effect of prostaglandin E2 in cultured guinea pig tracheal smooth muscle cells

Mechanical responses of tracheal tissue in vitro: dependence on the tissue preparation employed and relationship to smooth muscle content

AUTOMATED RECONSTRUCTION OF HISTORIC ROOF STRUCTURES FROM POINT CLOUDS – DEVELOPMENT AND EXAMPLES

vasa is required for GURKEN accumulation in the oocyte, and is involved in oocyte differentiation and germline cyst development

Concurrent validity and reliability of measuring range of motion during the cervical flexion rotation test with a novel digital goniometer

Development of a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor (MK-8245) to Establish a Therapeutic Window for the Treatment of Diabetes and Dyslipidemia

Correction to: Concurrent validity and reliability of measuring range of motion during the cervical flexion rotation test with a novel digital goniometer

DIGITAL WORKFLOWS FOR RESTORATION AND MANAGEMENT OF THE MUSEUM AFFANDI - A CASE STUDY IN CHALLENGING CIRCUMSTANCES

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