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Assembly, structure, function and regulation of type III secretion systems

Nature reviews. Microbiology, 2017-06, Vol.15 (6), p.323-337

2017

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X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation

Nature communications, 2022-09, Vol.13 (1), p.5196-5196, Article 5196

2022

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New Delhi Metallo-β-Lactamase: Structural Insights into β-Lactam Recognition and Inhibition

Journal of the American Chemical Society, 2012-07, Vol.134 (28), p.11362-11365

2012

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Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry

Nature communications, 2019-02, Vol.10 (1), p.626-12, Article 626

2019

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Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site

Nature communications, 2020-11, Vol.11 (1), p.5877-5877, Article 5877

2020

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Structural Perspective of Peptidoglycan Biosynthesis and Assembly

Annual review of biochemistry, 2012-01, Vol.81 (1), p.451-478

2012

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Aligning the Symmetry of the Type III Secretion System Needle Complex

Journal of chemical information and modeling, 2020-05, Vol.60 (5), p.2430-2435

2020

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Structural Insight into the Transglycosylation Step of Bacterial Cell-Wall Biosynthesis

Science (American Association for the Advancement of Science), 2007-03, Vol.315 (5817), p.1402-1405

2007

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High-Level Resistance of Staphylococcus aureus to β-Lactam Antibiotics Mediated by Penicillin-Binding Protein 4 (PBP4)

Antimicrobial agents and chemotherapy, 2017-06, Vol.61 (6)

2017

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Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli

Nature communications, 2019-04, Vol.10 (1), p.1849-11, Article 1849

2019

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Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase

Proceedings of the National Academy of Sciences - PNAS, 2015-09, Vol.112 (35), p.11048-11053

2015

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CryoEM structure of the antibacterial target PBP1b at 3.3 Å resolution

Nature communications, 2021-05, Vol.12 (1), p.2775-2775, Article 2775

2021

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One ring to rule them all: Current trends in combating bacterial resistance to the β‐lactams

Protein science, 2016-04, Vol.25 (4), p.787-803

2016

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Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS

Nature, 2008-05, Vol.453 (7191), p.124-127

2008

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Crystal structure of an intramembranal phosphatase central to bacterial cell-wall peptidoglycan biosynthesis and lipid recycling

Nature communications, 2018-03, Vol.9 (1), p.1159-9, Article 1159

2018

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The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins

Inorganic chemistry, 2022-04, Vol.61 (14), p.5563-5571

2022

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A refined model of the prototypical Salmonella SPI-1 T3SS basal body reveals the molecular basis for its assembly

PLoS pathogens, 2013-04, Vol.9 (4), p.e1003307-e1003307

2013

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The Hinge Region of the Israeli Acute Paralysis Virus Internal Ribosome Entry Site Directs Ribosomal Positioning, Translational Activity, and Virus Infection

Journal of virology, 2022-03, Vol.96 (5), p.e0133021-e0133021

2022

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Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria

Journal of medicinal chemistry, 2021-09, Vol.64 (18), p.13540-13550

2021

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Signal Peptidases

Chemical reviews, 2002-12, Vol.102 (12), p.4549-4580

2002

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Crystal structure of the C‐terminal domain of the Salmonella type III secretion system export apparatus protein InvA

Protein science, 2010-05, Vol.19 (5), p.1091-1096

2010

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Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins

ACS chemical biology, 2016-04, Vol.11 (4), p.864-868

2016

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Structural characterization of the molecular platform for type III secretion system assembly

Nature, 2005-06, Vol.435 (7042), p.702-707

2005

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Molecular Mechanism of Avibactam-Mediated β‑Lactamase Inhibition

ACS infectious diseases, 2015-04, Vol.1 (4), p.175-184

2015

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On the road to structure-based development of anti-virulence therapeutics targeting the type III secretion system injectisome

MedChemComm, 2019-08, Vol.1 (8), p.1273-1289

2019

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Assembly, structure, function and regulation of type III secretion systems

X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation

New Delhi Metallo-β-Lactamase: Structural Insights into β-Lactam Recognition and Inhibition

Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry

Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site

Structural Perspective of Peptidoglycan Biosynthesis and Assembly

Aligning the Symmetry of the Type III Secretion System Needle Complex

Structural Insight into the Transglycosylation Step of Bacterial Cell-Wall Biosynthesis

High-Level Resistance of Staphylococcus aureus to β-Lactam Antibiotics Mediated by Penicillin-Binding Protein 4 (PBP4)

Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli

Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase

CryoEM structure of the antibacterial target PBP1b at 3.3 Å resolution

One ring to rule them all: Current trends in combating bacterial resistance to the β‐lactams

Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS

Crystal structure of an intramembranal phosphatase central to bacterial cell-wall peptidoglycan biosynthesis and lipid recycling

The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins

A refined model of the prototypical Salmonella SPI-1 T3SS basal body reveals the molecular basis for its assembly

The Hinge Region of the Israeli Acute Paralysis Virus Internal Ribosome Entry Site Directs Ribosomal Positioning, Translational Activity, and Virus Infection

Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria

Signal Peptidases

Crystal structure of the C‐terminal domain of the Salmonella type III secretion system export apparatus protein InvA

Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins

Structural characterization of the molecular platform for type III secretion system assembly

Molecular Mechanism of Avibactam-Mediated β‑Lactamase Inhibition

On the road to structure-based development of anti-virulence therapeutics targeting the type III secretion system injectisome

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