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A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate

Biochimica et biophysica acta, 2012-11, Vol.1823 (11), p.2069-2078

2012

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SUMO fusion technology for enhanced protein expression and purification in prokaryotes and eukaryotes

Methods in molecular biology (Clifton, N.J.), 2011-01, Vol.705, p.15

2011

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Enhanced protein expression in the baculovirus/insect cell system using engineered SUMO fusions

Protein expression and purification, 2008-11, Vol.62 (1), p.21-28

2008

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To fuse or not to fuse: What is your purpose?

Protein science, 2013-11, Vol.22 (11), p.1466-1477

2013

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Structural and Mutational Analyses of the Molecular Interactions between the Catalytic Domain of Factor XIa and the Kunitz Protease Inhibitor Domain of Protease Nexin 2

The Journal of biological chemistry, 2005-10, Vol.280 (43), p.36165-36175

2005

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Protein Microarrays for the Identification of Praja1 E3 Ubiquitin Ligase Substrates

Cell biochemistry and biophysics, 2011-06, Vol.60 (1-2), p.127-135

2011

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Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions

Journal of applied physics, 2005-02, Vol.280 (6), p.4704-4712

2005

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Bioluminescence assay platform for selective and sensitive detection of Ub/Ubl proteases

Biochimica et biophysica acta, 2012-11, Vol.1823 (11), p.2079-2086

2012

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Deubiquitylase, DeSUMOylase, and DeISGylase Activity Microarrays for Assay of Substrate Preference and Functional Modifiers

Molecular & cellular proteomics, 2011-01, Vol.10 (1), p.M110.002402-M110.002402, Article M110.002402

2011

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Design, Synthesis, and Biological Evaluation of Peptidomimetic Inhibitors of Factor XIa as Novel Anticoagulants

Journal of medicinal chemistry, 2006-12, Vol.49 (26), p.7781-7791

2006

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An abundantly secreted glycoprotein from Drosophila melanogaster is related to mammalian secretory proteins produced in rheumatoid tissues and by activated macrophages

Gene, 1995-02, Vol.153 (2), p.147-154

1995

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Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an α-ketothiazole arginine

Bioorganic & medicinal chemistry letters, 2006-06, Vol.16 (11), p.3049-3054

2006

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The three-dimensional structure of the ZAP-70 kinase domain in complex with staurosporine: implications for the design of selective inhibitors

The Journal of biological chemistry, 2004-10, Vol.279 (41), p.42818-42825

2004

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Inhibition of HSV-1 protease by benzoxazinones

Bioorganic & medicinal chemistry letters, 1996-10, Vol.6 (20), p.2463-2466

1996

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E3 and DUB substrate identification, and chain linkage profiling using microarrays

The FASEB journal, 2011-04, Vol.25, p.539.2-539.2

2011

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Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues

Nature (London), 1990-01, Vol.343 (6253), p.90-92

1990

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The Three-dimensional Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine

The Journal of biological chemistry, 2004-10, Vol.279 (41), p.42818-42825

2004

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Mutation of surface residues to promote crystallization of activated factor XI as a complex with benzamidine: an essential step for the iterative structure-based design of factor XI inhibitors

Acta crystallographica. Section D, Biological crystallography., 2005-10, Vol.61 (10), p.1418-1425

2005

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

Nature (London), 1994-12, Vol.372 (6508), p.739-746

1994

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Proteases of Retroviruses: Proceedings of the Colloquium C 52, 14th International Congress of Biochemistry, Prague, Czechoslovakia, July 10-15, 1988

Kostka, Vladimír

1, 2019

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Proteolysis of an active site peptide of lactate dehydrogenase by human immunodeficiency virus type 1 protease

Biochemistry (Easton), 1992-10, Vol.31 (42), p.10153-10168

1992

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Trypanosoma congolense: structure and molecular organization of the surface glycoproteins of two early bloodstream variants

Biochemistry (Easton), 1987-02, Vol.26 (3), p.796-805

1987

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Contemporary Methodology for Protein Structure Determination

Science (American Association for the Advancement of Science), 1984-10, Vol.226 (4672), p.304-311

1984

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Human Immunodeficiency Virus Protease Expressed in Escherichia coli Exhibits Autoprocessing and Specific Maturation of the Gag Precursor

Proceedings of the National Academy of Sciences - PNAS, 1987-12, Vol.84 (24), p.8903-8906

1987

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Inhibition of Human Immunodeficiency Virus 1 Protease in vitro: Rational Design of Substrate Analogue Inhibitors

Proceedings of the National Academy of Sciences - PNAS, 1989-12, Vol.86 (24), p.9752-9756

1989

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A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate

SUMO fusion technology for enhanced protein expression and purification in prokaryotes and eukaryotes

Enhanced protein expression in the baculovirus/insect cell system using engineered SUMO fusions

To fuse or not to fuse: What is your purpose?

Structural and Mutational Analyses of the Molecular Interactions between the Catalytic Domain of Factor XIa and the Kunitz Protease Inhibitor Domain of Protease Nexin 2

Protein Microarrays for the Identification of Praja1 E3 Ubiquitin Ligase Substrates

Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions

Bioluminescence assay platform for selective and sensitive detection of Ub/Ubl proteases

Deubiquitylase, DeSUMOylase, and DeISGylase Activity Microarrays for Assay of Substrate Preference and Functional Modifiers

Design, Synthesis, and Biological Evaluation of Peptidomimetic Inhibitors of Factor XIa as Novel Anticoagulants

An abundantly secreted glycoprotein from Drosophila melanogaster is related to mammalian secretory proteins produced in rheumatoid tissues and by activated macrophages

Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an α-ketothiazole arginine

The three-dimensional structure of the ZAP-70 kinase domain in complex with staurosporine: implications for the design of selective inhibitors

Inhibition of HSV-1 protease by benzoxazinones

E3 and DUB substrate identification, and chain linkage profiling using microarrays

Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues

The Three-dimensional Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine

Mutation of surface residues to promote crystallization of activated factor XI as a complex with benzamidine: an essential step for the iterative structure-based design of factor XI inhibitors

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

Proteases of Retroviruses: Proceedings of the Colloquium C 52, 14th International Congress of Biochemistry, Prague, Czechoslovakia, July 10-15, 1988

Proteolysis of an active site peptide of lactate dehydrogenase by human immunodeficiency virus type 1 protease

Trypanosoma congolense: structure and molecular organization of the surface glycoproteins of two early bloodstream variants

Contemporary Methodology for Protein Structure Determination

Human Immunodeficiency Virus Protease Expressed in Escherichia coli Exhibits Autoprocessing and Specific Maturation of the Gag Precursor

Inhibition of Human Immunodeficiency Virus 1 Protease in vitro: Rational Design of Substrate Analogue Inhibitors

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