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Pharmacodynamic Drug–Drug Interactions

Clinical pharmacology and therapeutics, 2019-06, Vol.105 (6), p.1395-1406

2019

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Alteration in Levels of Specific miRNAs and Their Potential Protein Targets between Human Pancreatic Cancer Samples, Adjacent Normal Tissue, and Xenografts Derived from These Tumors

Life (Basel, Switzerland), 2023-02, Vol.13 (3), p.608

2023

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Establishment and Characterisation by Expression Microarray of Patient-Derived Xenograft Panel of Human Pancreatic Adenocarcinoma Patients

International journal of molecular sciences, 2020-01, Vol.21 (3), p.962

2020

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Single-treatment tumor ablation with photodynamic liposomal irinotecan sucrosulfate

Translational oncology, 2022-05, Vol.19, p.101390-101390, Article 101390

2022

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Pharmacodynamic modeling of synergistic birinapant/paclitaxel interactions in pancreatic cancer cells

BMC cancer, 2020-10, Vol.20 (1), p.1024-19, Article 1024

2020

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Pharmacodynamic modeling of cell cycle and apoptotic effects of gemcitabine on pancreatic adenocarcinoma cells

Cancer chemotherapy and pharmacology, 2013-09, Vol.72 (3), p.553-563

2013

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Application of pharmacokinetic and pharmacodynamic analysis to the development of liposomal formulations for oncology

Pharmaceutics, 2014-03, Vol.6 (1), p.137-174

2014

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Physiologically-based pharmacokinetic and pharmacodynamic models for gemcitabine and birinapant in pancreatic cancer xenografts

Journal of pharmacokinetics and pharmacodynamics, 2018-10, Vol.45 (5), p.733-746

2018

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Proteomic Analysis of Combined Gemcitabine and Birinapant in Pancreatic Cancer Cells

Frontiers in pharmacology, 2018-02, Vol.9, p.84-84

2018

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A Comparative Quantitative LC-MS/MS Profiling Analysis of Human Pancreatic Adenocarcinoma, Adjacent-Normal Tissue, and Patient-Derived Tumour Xenografts

Proteomes, 2018-11, Vol.6 (4), p.45

2018

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Highly Reproducible Quantitative Proteomics Analysis of Pancreatic Cancer Cells Reveals Proteome-Level Effects of a Novel Combination Drug Therapy That Induces Cancer Cell Death via Metabolic Remodeling and Activation of the Extrinsic Apoptosis Pathway

Journal of proteome research, 2023-12, Vol.22 (12), p.3780-3792

2023

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Contributions of William Jusko to Development of Pharmacokinetic and Pharmacodynamic Models and Methods

Journal of pharmaceutical sciences, 2024-01, Vol.113 (1), p.2-10

2024

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Multi‐Scale Network Model Supported by Proteomics for Analysis of Combined Gemcitabine and Birinapant Effects in Pancreatic Cancer Cells

CPT: pharmacometrics and systems pharmacology, 2018-09, Vol.7 (9), p.549-561

2018

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Species-Deconvolved Proteomics for In Situ Investigation of Tumor-Stroma Interactions after Treatment of Pancreatic Cancer Patient-Derived Xenografts with Combined Gemcitabine and Paclitaxel

Journal of proteome research, 2023-07, Vol.22 (7), p.2436-2449

2023

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Current taxane formulations and emerging cabazitaxel delivery systems

Nano research, 2018-10, Vol.11 (10), p.5193-5218

2018

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Pharmacokinetics and pharmacodynamics of liposomal chemophototherapy with short drug-light intervals

Journal of controlled release, 2019-03, Vol.297, p.39-47

2019

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Synergistic interactions between sorafenib and everolimus in pancreatic cancer xenografts in mice

Cancer chemotherapy and pharmacology, 2013-05, Vol.71 (5), p.1231-1240

2013

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Development and Evaluation of Tri-Functional Immunoliposomes for the Treatment of HER2 Positive Breast Cancer

Pharmaceutical research, 2018-05, Vol.35 (5), p.95-14, Article 95

2018

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A Rapid, Reproducible, On-the-Fly Orthogonal Array Optimization Method for Targeted Protein Quantification by LC/MS and Its Application for Accurate and Sensitive Quantification of Carbonyl Reductases in Human Liver

Analytical chemistry (Washington), 2010-04, Vol.82 (7), p.2680-2689

2010

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Quantification of Doxorubicin and metabolites in rat plasma and small volume tissue samples by liquid chromatography/electrospray tandem mass spectroscopy

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004-09, Vol.808 (2), p.141-152

2004

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Systems Pharmacodynamic Model of Combined Gemcitabine and Trabectedin in Pancreatic Cancer Cells. Part II: Cell Cycle, DNA Damage Response, and Apoptosis Pathways

Journal of pharmaceutical sciences, 2024-01, Vol.113 (1), p.235-245

2024

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DR5-targeted, chemotherapeutic drug-loaded nanoparticles induce apoptosis and tumor regression in pancreatic cancer in vivo models

Journal of controlled release, 2020-08, Vol.324, p.610-619

2020

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Integrated PK/PD modeling relates Smoothened inhibitor biomarkers to the heterogeneous intratumor disposition of cetuximab in pancreatic cancer tumor models

Journal of pharmaceutical sciences, 2024-01, Vol.113 (1), p.72-84

2024

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Systems pharmacodynamic model of combined gemcitabine and trabectedin in pancreatic cancer cells. Part I.Çô Effects on signal transduction pathways related to tumor growth

Journal of pharmaceutical sciences, 2024-01, Vol.113 (1), p.214

2024

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Tumor Priming by SMO Inhibition Enhances Antibody Delivery and Efficacy in a Pancreatic Ductal Adenocarcinoma Model

Molecular cancer therapeutics, 2019-11, Vol.18 (11), p.2074-2084

2019

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Pharmacodynamic Drug–Drug Interactions

Alteration in Levels of Specific miRNAs and Their Potential Protein Targets between Human Pancreatic Cancer Samples, Adjacent Normal Tissue, and Xenografts Derived from These Tumors

Establishment and Characterisation by Expression Microarray of Patient-Derived Xenograft Panel of Human Pancreatic Adenocarcinoma Patients

Single-treatment tumor ablation with photodynamic liposomal irinotecan sucrosulfate

Pharmacodynamic modeling of synergistic birinapant/paclitaxel interactions in pancreatic cancer cells

Pharmacodynamic modeling of cell cycle and apoptotic effects of gemcitabine on pancreatic adenocarcinoma cells

Application of pharmacokinetic and pharmacodynamic analysis to the development of liposomal formulations for oncology

Physiologically-based pharmacokinetic and pharmacodynamic models for gemcitabine and birinapant in pancreatic cancer xenografts

Proteomic Analysis of Combined Gemcitabine and Birinapant in Pancreatic Cancer Cells

A Comparative Quantitative LC-MS/MS Profiling Analysis of Human Pancreatic Adenocarcinoma, Adjacent-Normal Tissue, and Patient-Derived Tumour Xenografts

Highly Reproducible Quantitative Proteomics Analysis of Pancreatic Cancer Cells Reveals Proteome-Level Effects of a Novel Combination Drug Therapy That Induces Cancer Cell Death via Metabolic Remodeling and Activation of the Extrinsic Apoptosis Pathway

Contributions of William Jusko to Development of Pharmacokinetic and Pharmacodynamic Models and Methods

Multi‐Scale Network Model Supported by Proteomics for Analysis of Combined Gemcitabine and Birinapant Effects in Pancreatic Cancer Cells

Species-Deconvolved Proteomics for In Situ Investigation of Tumor-Stroma Interactions after Treatment of Pancreatic Cancer Patient-Derived Xenografts with Combined Gemcitabine and Paclitaxel

Current taxane formulations and emerging cabazitaxel delivery systems

Pharmacokinetics and pharmacodynamics of liposomal chemophototherapy with short drug-light intervals

Synergistic interactions between sorafenib and everolimus in pancreatic cancer xenografts in mice

Development and Evaluation of Tri-Functional Immunoliposomes for the Treatment of HER2 Positive Breast Cancer

A Rapid, Reproducible, On-the-Fly Orthogonal Array Optimization Method for Targeted Protein Quantification by LC/MS and Its Application for Accurate and Sensitive Quantification of Carbonyl Reductases in Human Liver

Quantification of Doxorubicin and metabolites in rat plasma and small volume tissue samples by liquid chromatography/electrospray tandem mass spectroscopy

Systems Pharmacodynamic Model of Combined Gemcitabine and Trabectedin in Pancreatic Cancer Cells. Part II: Cell Cycle, DNA Damage Response, and Apoptosis Pathways

DR5-targeted, chemotherapeutic drug-loaded nanoparticles induce apoptosis and tumor regression in pancreatic cancer in vivo models

Integrated PK/PD modeling relates Smoothened inhibitor biomarkers to the heterogeneous intratumor disposition of cetuximab in pancreatic cancer tumor models

Systems pharmacodynamic model of combined gemcitabine and trabectedin in pancreatic cancer cells. Part I.Çô Effects on signal transduction pathways related to tumor growth

Tumor Priming by SMO Inhibition Enhances Antibody Delivery and Efficacy in a Pancreatic Ductal Adenocarcinoma Model

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