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Migraine therapeutics differentially modulate the CGRP pathway

Cephalalgia, 2021-04, Vol.41 (5), p.499-514

2021

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Response to letter to the Editor: Assessing migraine therapeutics

Cephalalgia, 2021-11, Vol.41 (13), p.1404-1406

2021

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Selective Inhibition of Trigeminovascular Neurons by Fremanezumab: A Humanized Monoclonal Anti-CGRP Antibody

The Journal of neuroscience, 2017-07, Vol.37 (30), p.7149-7163

2017

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Disease pathology signatures in a mouse model of Mucopolysaccharidosis type IIIB

Scientific reports, 2023-10, Vol.13 (1), p.16699-16699, Article 16699

2023

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Fremanezumab blocks CGRP induced dilatation in human cerebral, middle meningeal and abdominal arteries

Journal of headache and pain, 2018-08, Vol.19 (1), p.66-66, Article 66

2018

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Modifying antibody-FcRn interactions to increase the transport of antibodies through the blood-brain barrier

mAbs, 2023, Vol.15 (1), p.2229098-2229098

2023

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The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats

International journal of molecular sciences, 2023-09, Vol.24 (17), p.13471

2023

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Imiquimod-induced pruritus in female wild-type and knockin Wistar rats: underscoring behavioral scratching in a rat model for antipruritic treatments

BMC research notes, 2023-11, Vol.16 (1), p.1-348, Article 348

2023

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Immunogenicity of biologic therapies for migraine: a review of current evidence

Journal of headache and pain, 2021-01, Vol.22 (1), p.3-8, Article 3

2021

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An in vivo accelerated developmental myelination model for testing promyelinating therapeutics

BMC neuroscience, 2022-05, Vol.23 (1), p.30-30, Article 30

2022

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The Anti-CGRP Antibody Fremanezumab Lowers CGRP Release from Rat Dura Mater and Meningeal Blood Flow

Cells (Basel, Switzerland), 2022-05, Vol.11 (11), p.1768

2022

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Glycerol Trinitrate Acts Downstream of Calcitonin Gene-Related Peptide in Trigeminal Nociception-Evidence from Rodent Experiments with Anti-CGRP Antibody Fremanezumab

Cells (Basel, Switzerland), 2024-04, Vol.13 (7), p.572

2024

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Semi-Automated Recording of Facial Sensitivity in Rat Demonstrates Antinociceptive Effects of the Anti-CGRP Antibody Fremanezumab

Neurology international, 2023-04, Vol.15 (2), p.622-637

2023

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TrkB Agonists Ameliorate Obesity and Associated Metabolic Conditions in Mice

Endocrinology (Philadelphia), 2008-03, Vol.149 (3), p.1038-1048

2008

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Increased severity of closed head injury or repetitive subconcussive head impacts enhances post-traumatic headache-like behaviors in a rat model

Cephalalgia, 2020-10, Vol.40 (11), p.1224-1239

2020

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Enhanced post-traumatic headache-like behaviors and diminished contribution of peripheral CGRP in female rats following a mild closed head injury

Cephalalgia, 2020-06, Vol.40 (7), p.748-760

2020

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Fremanezumab-A Humanized Monoclonal Anti-CGRP Antibody-Inhibits Thinly Myelinated (Aδ) But Not Unmyelinated (C) Meningeal Nociceptors

The Journal of neuroscience, 2017-11, Vol.37 (44), p.10587-10596

2017

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Appetite enhancement and weight gain by peripheral administration of TrkB agonists in non-human primates

PloS one, 2008-04, Vol.3 (4), p.e1900

2008

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CSD-Induced Arterial Dilatation and Plasma Protein Extravasation Are Unaffected by Fremanezumab: Implications for CGRP's Role in Migraine with Aura

The Journal of neuroscience, 2019-07, Vol.39 (30), p.6001-6011

2019

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CGRP-dependent and independent mechanisms of acute and persistent post-traumatic headache following mild traumatic brain injury in mice

Cephalalgia, 2019-12, Vol.39 (14), p.1762-1775

2019

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Fluorescently-labeled fremanezumab is distributed to sensory and autonomic ganglia and the dura but not to the brain of rats with uncompromised blood brain barrier

Cephalalgia, 2020-03, Vol.40 (3), p.229-240

2020

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Spontaneous epidural hematoma of the thoracic spine in a 17-year-old adolescent boy: a case report

The American journal of emergency medicine, 2009-06, Vol.27 (5), p.628.e5-628.e6

2009

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Fremanezumab and its isotype slow propagation rate and shorten cortical recovery period but do not prevent occurrence of cortical spreading depression in rats with compromised blood-brain barrier

Pain (Amsterdam), 2020-05, Vol.161 (5), p.1037

2020

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A Monoclonal Anti-Calcitonin Gene-Related Peptide Antibody Decreases Stress-Induced Colonic Hypersensitivity

The Journal of pharmacology and experimental therapeutics, 2021-12, Vol.379 (3), p.270

2021

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Tu1647 CHRONIC STRESS INDUCES COLONIC HYPERSENSITIVITY IN A HUMANIZED PROTEINASE-ACTIVATED RECEPTOR 2 KNOCK-IN RAT

Gastroenterology (New York, N.Y. 1943), 2023-05, Vol.164 (6), p.S-1072-S-1072

2023

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Migraine therapeutics differentially modulate the CGRP pathway

Response to letter to the Editor: Assessing migraine therapeutics

Selective Inhibition of Trigeminovascular Neurons by Fremanezumab: A Humanized Monoclonal Anti-CGRP Antibody

Disease pathology signatures in a mouse model of Mucopolysaccharidosis type IIIB

Fremanezumab blocks CGRP induced dilatation in human cerebral, middle meningeal and abdominal arteries

Modifying antibody-FcRn interactions to increase the transport of antibodies through the blood-brain barrier

The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats

Imiquimod-induced pruritus in female wild-type and knockin Wistar rats: underscoring behavioral scratching in a rat model for antipruritic treatments

Immunogenicity of biologic therapies for migraine: a review of current evidence

An in vivo accelerated developmental myelination model for testing promyelinating therapeutics

The Anti-CGRP Antibody Fremanezumab Lowers CGRP Release from Rat Dura Mater and Meningeal Blood Flow

Glycerol Trinitrate Acts Downstream of Calcitonin Gene-Related Peptide in Trigeminal Nociception-Evidence from Rodent Experiments with Anti-CGRP Antibody Fremanezumab

Semi-Automated Recording of Facial Sensitivity in Rat Demonstrates Antinociceptive Effects of the Anti-CGRP Antibody Fremanezumab

TrkB Agonists Ameliorate Obesity and Associated Metabolic Conditions in Mice

Increased severity of closed head injury or repetitive subconcussive head impacts enhances post-traumatic headache-like behaviors in a rat model

Enhanced post-traumatic headache-like behaviors and diminished contribution of peripheral CGRP in female rats following a mild closed head injury

Fremanezumab-A Humanized Monoclonal Anti-CGRP Antibody-Inhibits Thinly Myelinated (Aδ) But Not Unmyelinated (C) Meningeal Nociceptors

Appetite enhancement and weight gain by peripheral administration of TrkB agonists in non-human primates

CSD-Induced Arterial Dilatation and Plasma Protein Extravasation Are Unaffected by Fremanezumab: Implications for CGRP's Role in Migraine with Aura

CGRP-dependent and independent mechanisms of acute and persistent post-traumatic headache following mild traumatic brain injury in mice

Fluorescently-labeled fremanezumab is distributed to sensory and autonomic ganglia and the dura but not to the brain of rats with uncompromised blood brain barrier

Spontaneous epidural hematoma of the thoracic spine in a 17-year-old adolescent boy: a case report

Fremanezumab and its isotype slow propagation rate and shorten cortical recovery period but do not prevent occurrence of cortical spreading depression in rats with compromised blood-brain barrier

A Monoclonal Anti-Calcitonin Gene-Related Peptide Antibody Decreases Stress-Induced Colonic Hypersensitivity

Tu1647 CHRONIC STRESS INDUCES COLONIC HYPERSENSITIVITY IN A HUMANIZED PROTEINASE-ACTIVATED RECEPTOR 2 KNOCK-IN RAT

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