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Computational Support to Explore Ternary Solid Dispersions of Challenging Drugs Using Coformer and Hydroxypropyl Cellulose

Molecular pharmaceutics, 2024-10

2024

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Phase homogeneity in ternary amorphous solid dispersions and its impact on solubility, dissolution and supersaturation - Influence of processing and hydroxypropyl cellulose grade

International journal of pharmaceutics: X, 2023-12, Vol.6, p.100222-100222, Article 100222

2023

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Tailored ASD destabilization - Balancing shelf life stability and dissolution performance with hydroxypropyl cellulose

International journal of pharmaceutics: X, 2023-12, Vol.5, p.100187-100187, Article 100187

2023

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Physiological Buffer Effects in Drug Supersaturation - A Mechanistic Study of Hydroxypropyl Cellulose as Precipitation Inhibitor

Journal of pharmaceutical sciences, 2023-07, Vol.112 (7), p.1897-1907

2023

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Liquid crystalline phase behavior and hydration of hydroxypropyl cellulose in water: A liquid and solid NMR investigation

Journal of polymer science (2020), 2023-04, Vol.61 (8), p.646-658

2023

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Boost of solubility and supersaturation of celecoxib via synergistic interactions of methacrylic acid-ethyl acrylate copolymer (1:1) and hydroxypropyl cellulose in ternary amorphous solid dispersions

International journal of pharmaceutics: X, 2022-12, Vol.4, p.100115-100115, Article 100115

2022

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Hydroxypropyl Cellulose for Drug Precipitation Inhibition: From the Potential of Molecular Interactions to Performance Considering Microrheology

Molecular pharmaceutics, 2022-02, Vol.19 (2), p.690-703

2022

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Phase behavior of ASDs based on hydroxypropyl cellulose

International journal of pharmaceutics: X, 2021-12, Vol.3, p.100070-100070, Article 100070

2021

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In vitro and in vivo assessment of hydroxypropyl cellulose as functional additive for enabling formulations containing itraconazole

International journal of pharmaceutics: X, 2021-12, Vol.3, p.100076-100076, Article 100076

2021

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New insights into the use of hydroxypropyl cellulose for drug solubility enhancement: An analytical study of sub‐molecular interactions with fenofibrate in solid state and aqueous solutions

Journal of polymer science (2020), 2021-08, Vol.59 (16), p.1855-1865

2021

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Mechanism of interaction between hydroxypropyl cellulose and water in aqueous solutions: Importance of polymer chain length

Journal of polymer science (2020), 2020-06, Vol.58 (12), p.1632-1641

2020

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3D printed opioid medicines with alcohol-resistant and abuse-deterrent properties

International journal of pharmaceutics, 2020-04, Vol.579, p.119169, Article 119169

2020

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Differential Analysis of O-(2- hydroxypropyl) cellulose by Using Two-Dimensional 1H-NMR Spectroscopy

Archive of Biomedical Science and Engineering, 2020-03, Vol.6 (1), p.10-15

2020

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Direct powder extrusion 3D printing: Fabrication of drug products using a novel single-step process

International journal of pharmaceutics, 2019-08, Vol.567, p.118471-118471, Article 118471

2019

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Powder bed 3D-printing of highly loaded drug delivery devices with hydroxypropyl cellulose as solid binder

International journal of pharmaceutics, 2019-01, Vol.555, p.198-206

2019

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Competing for water: A new approach to understand disintegrant performance

International journal of pharmaceutics, 2018-09, Vol.548 (1), p.491-499

2018

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Orthoamides and Iminium Salts, LXXI. Capturing of Carbon Dioxide with Organic Bases (Part 2) - Reactions of Guanidines and omega-Aminoalkyl-guanidines with Carbon Dioxide (In German)

Zeitschrift für Naturforschung. B, A journal of chemical sciences, 2011-04, Vol.66, p.407

2011

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Orthoamide und Iminiumsalze, LXXI [1]. Zur Fixierung von Kohlendioxid mit organischen Basen (Teil 2) – Reaktionen von Guanidinen und ω-Aminoalkyl-guanidinen mit Kohlendioxid/ Orthoamides and IminiumSalts, LXXI [1]. Capturing of Carbon Dioxidewith OrganicBases (Part 2) – Reactions of Guanidines and ω-Aminoalkyl-guanidines with Carbon Dioxide

Zeitschrift für Naturforschung. B, A journal of chemical sciences, 2011-04, Vol.66 (4), p.407-418

2011

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An all-round excipient for direct compression

Pharmaceutical technology Europe, 2010-10, Vol.22 (10), p.34

2010

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An all-round excipient for direct compression: in the past, many efforts have been made to develop a single excipient that incorporates the properties of a binder, disintegrant and lubricant, and which can also be used for direct compression of an API. Using new co-processing technologies, the authors show that it is possible to formulate such an 'all-round' excipient

Pharmaceutical technology Europe, 2010-10, Vol.22 (10), p.34

2010

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A New Synthesis of N , N ′-Bis(dimethylaminomethylene)hydrazine

Synthesis (Stuttgart), 2008-11, Vol.2008 (21), p.3380-3382

2008

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ChemInform Abstract: Orthoamide. Part 67. Bis(diformylamino)methane - A New Efficient Formylating Reagent for Aromatic Compounds

ChemInform, 2008-07, Vol.39 (30), p.no-no

2008

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Orthoamide, LXVII [1]. Bis(diformylamino)methan – ein neues leistungsfähiges Formylierungsmittel für aromatische Verbindungen / Orthoamides, LXVII [1]. Bis(diformylamino)methane – a New Efficient Formylating Reagent for Aromatic Compounds

Zeitschrift für Naturforschung. B, A journal of chemical sciences, 2008-04, Vol.63 (4), p.395-406

2008

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Fries Rearrangement of Aryl Formates: A Mechanistic Study by Means of 1H, 2H, and 11B NMR Spectroscopy and DFT Calculations

Journal of organic chemistry, 2006-12, Vol.71 (25), p.9331-9340

2006

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Fries Rearrangement of Aryl Formates: A Mechanistic Study by Means of 1 H, 2 H, and 11 B NMR Spectroscopy and DFT Calculations

Journal of organic chemistry, 2006-12, Vol.71 (25), p.9331-9340

2006

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Computational Support to Explore Ternary Solid Dispersions of Challenging Drugs Using Coformer and Hydroxypropyl Cellulose

Phase homogeneity in ternary amorphous solid dispersions and its impact on solubility, dissolution and supersaturation - Influence of processing and hydroxypropyl cellulose grade

Tailored ASD destabilization - Balancing shelf life stability and dissolution performance with hydroxypropyl cellulose

Physiological Buffer Effects in Drug Supersaturation - A Mechanistic Study of Hydroxypropyl Cellulose as Precipitation Inhibitor

Liquid crystalline phase behavior and hydration of hydroxypropyl cellulose in water: A liquid and solid NMR investigation

Boost of solubility and supersaturation of celecoxib via synergistic interactions of methacrylic acid-ethyl acrylate copolymer (1:1) and hydroxypropyl cellulose in ternary amorphous solid dispersions

Hydroxypropyl Cellulose for Drug Precipitation Inhibition: From the Potential of Molecular Interactions to Performance Considering Microrheology

Phase behavior of ASDs based on hydroxypropyl cellulose

In vitro and in vivo assessment of hydroxypropyl cellulose as functional additive for enabling formulations containing itraconazole

New insights into the use of hydroxypropyl cellulose for drug solubility enhancement: An analytical study of sub‐molecular interactions with fenofibrate in solid state and aqueous solutions

Mechanism of interaction between hydroxypropyl cellulose and water in aqueous solutions: Importance of polymer chain length

3D printed opioid medicines with alcohol-resistant and abuse-deterrent properties

Differential Analysis of O-(2- hydroxypropyl) cellulose by Using Two-Dimensional 1H-NMR Spectroscopy

Direct powder extrusion 3D printing: Fabrication of drug products using a novel single-step process

Powder bed 3D-printing of highly loaded drug delivery devices with hydroxypropyl cellulose as solid binder

Competing for water: A new approach to understand disintegrant performance

Orthoamides and Iminium Salts, LXXI. Capturing of Carbon Dioxide with Organic Bases (Part 2) - Reactions of Guanidines and omega-Aminoalkyl-guanidines with Carbon Dioxide (In German)

An all-round excipient for direct compression

A New Synthesis of N , N ′-Bis(dimethylaminomethylene)hydrazine

ChemInform Abstract: Orthoamide. Part 67. Bis(diformylamino)methane - A New Efficient Formylating Reagent for Aromatic Compounds

Orthoamide, LXVII [1]. Bis(diformylamino)methan – ein neues leistungsfähiges Formylierungsmittel für aromatische Verbindungen / Orthoamides, LXVII [1]. Bis(diformylamino)methane – a New Efficient Formylating Reagent for Aromatic Compounds

Fries Rearrangement of Aryl Formates: A Mechanistic Study by Means of 1H, 2H, and 11B NMR Spectroscopy and DFT Calculations

Fries Rearrangement of Aryl Formates: A Mechanistic Study by Means of 1 H, 2 H, and 11 B NMR Spectroscopy and DFT Calculations

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