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Enfortumab Vedotin Antibody-Drug Conjugate Targeting Nectin-4 Is a Highly Potent Therapeutic Agent in Multiple Preclinical Cancer Models

Cancer research (Chicago, Ill.), 2016-05, Vol.76 (10), p.3003-3013

2016

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Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma

Blood, 2009-07, Vol.114 (2), p.371-379

2009

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Modulation of Macropinocytosis-Mediated Internalization Decreases Ocular Toxicity of Antibody-Drug Conjugates

Cancer research (Chicago, Ill.), 2018-04, Vol.78 (8), p.2115-2126

2018

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Inhibiting Dickkopf‐1 (Dkk1) Removes Suppression of Bone Formation and Prevents the Development of Osteolytic Bone Disease in Multiple Myeloma

Journal of bone and mineral research, 2009-03, Vol.24 (3), p.425-436

2009

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Inhibition of Megakaryocyte Differentiation by Antibody-Drug Conjugates (ADCs) is Mediated by Macropinocytosis: Implications for ADC-induced Thrombocytopenia

Molecular cancer therapeutics, 2017-09, Vol.16 (9), p.1877-1886

2017

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Discoidin domain receptor 1 contributes to tumorigenesis through modulation of TGFBI expression

PloS one, 2014-11, Vol.9 (11), p.e111515

2014

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The Discovery and Preclinical Development of ASG-5ME, an Antibody-Drug Conjugate Targeting SLC44A4-Positive Epithelial Tumors Including Pancreatic and Prostate Cancer

Molecular cancer therapeutics, 2016-11, Vol.15 (11), p.2679-2687

2016

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A Potential Mechanism for ADC-Induced Neutropenia: Role of Neutrophils in Their Own Demise

Molecular cancer therapeutics, 2017-09, Vol.16 (9), p.1866-1876

2017

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Development of ASG-15ME, a Novel Antibody-Drug Conjugate Targeting SLITRK6, a New Urothelial Cancer Biomarker

Molecular cancer therapeutics, 2016-06, Vol.15 (6), p.1301-1310

2016

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AGS67E, an Anti-CD37 Monomethyl Auristatin E Antibody-Drug Conjugate as a Potential Therapeutic for B/T-Cell Malignancies and AML: A New Role for CD37 in AML

Molecular cancer therapeutics, 2015-07, Vol.14 (7), p.1650-1660

2015

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AGS16F Is a Novel Antibody Drug Conjugate Directed against ENPP3 for the Treatment of Renal Cell Carcinoma

Clinical cancer research, 2016-04, Vol.22 (8), p.1989-1999

2016

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Abstract 3853: Potential mechanisms for thrombocytopenia and neutropenia induced by antibody-drug conjugates

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.3853-3853

2016

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Preclinical Evaluation of an Anti-Nectin-4 ImmunoPET Reagent in Tumor-Bearing Mice and Biodistribution Studies in Cynomolgus Monkeys

Molecular imaging and biology, 2016-10, Vol.18 (5), p.768-775

2016

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Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors

Structure (London), 1999-06, Vol.7 (6), p.651-661

1999

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Abstract 574: AGS62P1, a novel site-specific antibody drug conjugate targeting FLT3 exhibits potent anti-tumor activity regardless of FLT3 kinase activation status

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.574-574

2016

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TRAIL signals to apoptosis in chronic lymphocytic leukaemia cells primarily through TRAIL‐R1 whereas cross‐linked agonistic TRAIL‐R2 antibodies facilitate signalling via TRAIL‐R2

British journal of haematology, 2007-11, Vol.139 (4), p.568-577

2007

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Abstract 1726: Preclinical evaluation of a novel tumor selectively targeted and activated immunocytokine platform

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1726-1726

2021

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Abstract 1581: Nammisomes: Preclinical validation of a platform for selective and synchronized delivery of novel immunotherapy prodrug combinations to tumors

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1581-1581

2021

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Protein-Tyrosine-Phosphatase CD45 is Phosphorylated Transiently on Tyrosine Upon Activation of Jurkat T Cells

Proceedings of the National Academy of Sciences - PNAS, 1991-09, Vol.88 (17), p.7704-7707

1991

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Differential phosphoprofiles of EGF and EGFR kinase inhibitor-treated human tumor cells and mouse xenografts

Clinical proteomics, 2004, Vol.1 (1), p.69-80

2004

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How leadership networks strengthen people and organizations

Leader to leader, 2004-03, Vol.2004 (32), p.56-62

2004

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Novel magnetic supports for small molecule affinity capture of proteins for use in proteomics

Molecular diversity, 2004, Vol.8 (1), p.9-19

2004

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Abstract 1976: MDR expression/ activity may serve as potential biomarker in developing therapeutic drugs for AML therapy

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.1976-1976

2014

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Src Phosphorylation of the Epidermal Growth Factor Receptor at Novel Sites Mediates Receptor Interaction with Src and P85α(∗)

The Journal of biological chemistry, 1995-06, Vol.270 (26), p.15591-15597

1995

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Enfortumab Vedotin Antibody-Drug Conjugate Targeting Nectin-4 Is a Highly Potent Therapeutic Agent in Multiple Preclinical Cancer Models

Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma

Modulation of Macropinocytosis-Mediated Internalization Decreases Ocular Toxicity of Antibody-Drug Conjugates

Inhibiting Dickkopf‐1 (Dkk1) Removes Suppression of Bone Formation and Prevents the Development of Osteolytic Bone Disease in Multiple Myeloma

Inhibition of Megakaryocyte Differentiation by Antibody-Drug Conjugates (ADCs) is Mediated by Macropinocytosis: Implications for ADC-induced Thrombocytopenia

Discoidin domain receptor 1 contributes to tumorigenesis through modulation of TGFBI expression

The Discovery and Preclinical Development of ASG-5ME, an Antibody-Drug Conjugate Targeting SLC44A4-Positive Epithelial Tumors Including Pancreatic and Prostate Cancer

A Potential Mechanism for ADC-Induced Neutropenia: Role of Neutrophils in Their Own Demise

Development of ASG-15ME, a Novel Antibody-Drug Conjugate Targeting SLITRK6, a New Urothelial Cancer Biomarker

AGS67E, an Anti-CD37 Monomethyl Auristatin E Antibody-Drug Conjugate as a Potential Therapeutic for B/T-Cell Malignancies and AML: A New Role for CD37 in AML

AGS16F Is a Novel Antibody Drug Conjugate Directed against ENPP3 for the Treatment of Renal Cell Carcinoma

Abstract 3853: Potential mechanisms for thrombocytopenia and neutropenia induced by antibody-drug conjugates

Preclinical Evaluation of an Anti-Nectin-4 ImmunoPET Reagent in Tumor-Bearing Mice and Biodistribution Studies in Cynomolgus Monkeys

Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors

Abstract 574: AGS62P1, a novel site-specific antibody drug conjugate targeting FLT3 exhibits potent anti-tumor activity regardless of FLT3 kinase activation status

TRAIL signals to apoptosis in chronic lymphocytic leukaemia cells primarily through TRAIL‐R1 whereas cross‐linked agonistic TRAIL‐R2 antibodies facilitate signalling via TRAIL‐R2

Abstract 1726: Preclinical evaluation of a novel tumor selectively targeted and activated immunocytokine platform

Abstract 1581: Nammisomes: Preclinical validation of a platform for selective and synchronized delivery of novel immunotherapy prodrug combinations to tumors

Protein-Tyrosine-Phosphatase CD45 is Phosphorylated Transiently on Tyrosine Upon Activation of Jurkat T Cells

Differential phosphoprofiles of EGF and EGFR kinase inhibitor-treated human tumor cells and mouse xenografts

How leadership networks strengthen people and organizations

Novel magnetic supports for small molecule affinity capture of proteins for use in proteomics

Abstract 1976: MDR expression/ activity may serve as potential biomarker in developing therapeutic drugs for AML therapy

AGS62P1, a Novel Anti-FLT3 Antibody Drug Conjugate, Employing Site Specific Conjugation, Demonstrates Preclinical Anti-Tumor Efficacy in AML Tumor and Patient Derived Xenografts

Src Phosphorylation of the Epidermal Growth Factor Receptor at Novel Sites Mediates Receptor Interaction with Src and P85α(∗)

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