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Abundance of P‐Glycoprotein and Other Drug Transporters at the Human Blood‐Brain Barrier in Alzheimer’s Disease: A Quantitative Targeted Proteomic Study

Clinical pharmacology and therapeutics, 2021-03, Vol.109 (3), p.667-675

2021

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Successful Prediction of Human Steady‐State Unbound Brain‐to‐Plasma Concentration Ratio of P‐gp Substrates Using the Proteomics‐Informed Relative Expression Factor Approach

Clinical pharmacology and therapeutics, 2021-08, Vol.110 (2), p.432-442

2021

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Physiologically‐Based Pharmacokinetic Modeling for the Prediction of CYP2D6‐Mediated Gene–Drug–Drug Interactions

CPT: pharmacometrics and systems pharmacology, 2019-08, Vol.8 (8), p.567-576

2019

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Genotype-sensitive reversible and time-dependent CYP2D6 Inhibition in human liver microsomes

Drug metabolism and pharmacokinetics, 2019-01, Vol.34 (1), p.S41-S42

2019

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Pharmacogenomics of Oral Antithrombotic Drugs

Current pharmaceutical design, 2016-04, Vol.22 (13), p.1933-1949

2016

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Evaluation of Pupillometry for CYP2D6 Phenotyping in Children Treated with Tramadol

Pharmaceuticals (Basel, Switzerland), 2023-08, Vol.16 (9), p.1227

2023

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P22 - Endobiotics for phenotyping of human cytochrome P450 enzymes: Use of metabolomics for the identification of new CYP2D6 endogenous biomarkers on healthy volunteers

Drug metabolism and pharmacokinetics, 2020, Vol.35 (1), p.S28-S28

2020

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Toward improved predictions of pharmacokinetics of transported drugs in hepatic impairment: Insights from the extended clearance model

CPT: pharmacometrics and systems pharmacology, 2024-01, Vol.13 (1), p.118-131

2024

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Predicting changes in the pharmacokinetics of CYP3A‐metabolized drugs in hepatic impairment and insights into factors driving these changes

CPT: pharmacometrics and systems pharmacology, 2023-02, Vol.12 (2), p.261-273

2023

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Is Protein‐Mediated Uptake Of Drugs By OATPs, Via Protein‐Lipid Interaction, A Real Phenomenon Or An Artifact?

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Successful Prediction of Human Fetal Exposure to P-Glycoprotein Substrate Drugs Using the Proteomics-Informed Relative Expression Factor Approach and PBPK Modeling and Simulation

Drug metabolism and disposition, 2021-10, Vol.49 (10), p.919-928

2021

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The Association of Combined GSTM1 and CYP2C9 Genotype Status with the Occurrence of Hemorrhagic Cystitis in Pediatric Patients Receiving Myeloablative Conditioning Regimen Prior to Allogeneic Hematopoietic Stem Cell Transplantation

Frontiers in pharmacology, 2017-07, Vol.8, p.451-451

2017

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Is the Protein-Mediated Uptake of Drugs by Organic Anion Transporting Polypeptides a Real Phenomenon or an Artifact?

Drug metabolism and disposition, 2022-09, Vol.50 (9), p.1132-1141

2022

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Complex Drug–Drug–Gene–Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives

Clinical pharmacokinetics, 2018-10, Vol.57 (10), p.1267-1293

2018

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Impact of CYP2D6 Functional Allelic Variations on Phenoconversion and Drug–Drug Interactions

Clinical pharmacology and therapeutics, 2018-07, Vol.104 (1), p.148-157

2018

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Genotype‐sensitive reversible and time‐dependent CYP 2D6 inhibition in human liver microsomes

Basic & clinical pharmacology & toxicology, 2019-02, Vol.124 (2), p.170-180

2019

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Genotype‐sensitive reversible and time‐dependent CYP2D6 inhibition in human liver microsomes

Basic & clinical pharmacology & toxicology, 2019-02, Vol.124 (2), p.170-180

2019

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The next frontier in ADME science: Predicting transporter-based drug disposition, tissue concentrations and drug-drug interactions in humans

Pharmacology & therapeutics (Oxford), 2022-10, Vol.238, p.108271, Article 108271

2022

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Is The Protein-Mediated Uptake Of Drugs By OATPs A Real Phenomenon Or An Artifact?

Drug metabolism and disposition, 2022-03

2022

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Prediction of Hepatobiliary Clearances and Hepatic Concentrations of Transported Drugs in Humans Using Rosuvastatin as a Model Drug

Clinical pharmacology and therapeutics, 2022-09, Vol.112 (3), p.593-604

2022

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27 Can pupillometry be used for CYP2D6 phenotyping in children treated with tramadol?

BMJ paediatrics open, 2024-08, Vol.8 (Suppl 6), p.A13-A13

2024

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Recent advances in drug transporter sciences: highlights from the year 2020

Drug metabolism reviews, 2021-07, Vol.53 (3), p.321-349

2021

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Detection and Identification of Reactive Drug Metabolites Leading to Idiosyncratic Toxicity: Lapatinib as a Case Example

Journal of drug metabolism & toxicology, 2018, Vol.9 (3)

2018

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The Next Frontier in ADME Science: Predicting Transporter-Based Drug Disposition, Tissue Concentrations and Drug-Drug Interactions in Humans

SSRN Electronic Journal

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Behaviour of Escherichia coli O157:H7 in raw and mild pasteurised donkey milk treated with high pressure

International dairy journal, 2023-01, Vol.136, p.105486, Article 105486

2023

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Abundance of P‐Glycoprotein and Other Drug Transporters at the Human Blood‐Brain Barrier in Alzheimer’s Disease: A Quantitative Targeted Proteomic Study

Successful Prediction of Human Steady‐State Unbound Brain‐to‐Plasma Concentration Ratio of P‐gp Substrates Using the Proteomics‐Informed Relative Expression Factor Approach

Physiologically‐Based Pharmacokinetic Modeling for the Prediction of CYP2D6‐Mediated Gene–Drug–Drug Interactions

Genotype-sensitive reversible and time-dependent CYP2D6 Inhibition in human liver microsomes

Pharmacogenomics of Oral Antithrombotic Drugs

Evaluation of Pupillometry for CYP2D6 Phenotyping in Children Treated with Tramadol

P22 - Endobiotics for phenotyping of human cytochrome P450 enzymes: Use of metabolomics for the identification of new CYP2D6 endogenous biomarkers on healthy volunteers

Toward improved predictions of pharmacokinetics of transported drugs in hepatic impairment: Insights from the extended clearance model

Predicting changes in the pharmacokinetics of CYP3A‐metabolized drugs in hepatic impairment and insights into factors driving these changes

Is Protein‐Mediated Uptake Of Drugs By OATPs, Via Protein‐Lipid Interaction, A Real Phenomenon Or An Artifact?

Successful Prediction of Human Fetal Exposure to P-Glycoprotein Substrate Drugs Using the Proteomics-Informed Relative Expression Factor Approach and PBPK Modeling and Simulation

The Association of Combined GSTM1 and CYP2C9 Genotype Status with the Occurrence of Hemorrhagic Cystitis in Pediatric Patients Receiving Myeloablative Conditioning Regimen Prior to Allogeneic Hematopoietic Stem Cell Transplantation

Is the Protein-Mediated Uptake of Drugs by Organic Anion Transporting Polypeptides a Real Phenomenon or an Artifact?

Complex Drug–Drug–Gene–Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives

Impact of CYP2D6 Functional Allelic Variations on Phenoconversion and Drug–Drug Interactions

Genotype‐sensitive reversible and time‐dependent CYP 2D6 inhibition in human liver microsomes

Genotype‐sensitive reversible and time‐dependent CYP2D6 inhibition in human liver microsomes

The next frontier in ADME science: Predicting transporter-based drug disposition, tissue concentrations and drug-drug interactions in humans

Is The Protein-Mediated Uptake Of Drugs By OATPs A Real Phenomenon Or An Artifact?

Prediction of Hepatobiliary Clearances and Hepatic Concentrations of Transported Drugs in Humans Using Rosuvastatin as a Model Drug

27 Can pupillometry be used for CYP2D6 phenotyping in children treated with tramadol?

Recent advances in drug transporter sciences: highlights from the year 2020

Detection and Identification of Reactive Drug Metabolites Leading to Idiosyncratic Toxicity: Lapatinib as a Case Example

The Next Frontier in ADME Science: Predicting Transporter-Based Drug Disposition, Tissue Concentrations and Drug-Drug Interactions in Humans

Behaviour of Escherichia coli O157:H7 in raw and mild pasteurised donkey milk treated with high pressure

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