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HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells

PLoS pathogens, 2019-07, Vol.15 (7), p.e1007883-e1007883

2019

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Constitutively Active MAVS Inhibits HIV-1 Replication via Type I Interferon Secretion and Induction of HIV-1 Restriction Factors

PloS one, 2016-02, Vol.11 (2), p.e0148929-e0148929

2016

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Epstein Barr virus Latent Membrane Protein-1 enhances dendritic cell therapy lymph node migration, activation, and IL-12 secretion

PloS one, 2017-09, Vol.12 (9), p.e0184915-e0184915

2017

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A multi-trimeric fusion of CD40L and gp100 tumor antigen activates dendritic cells and enhances survival in a B16-F10 melanoma DNA vaccine model

Vaccine, 2015-09, Vol.33 (38), p.4798-4806

2015

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Nanoparticle-delivered multimeric soluble CD40L DNA combined with Toll-Like Receptor agonists as a treatment for melanoma

PloS one, 2009-10, Vol.4 (10), p.e7334-e7334

2009

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HIV-1 adenoviral vector vaccines expressing multi-trimeric BAFF and 4-1BBL enhance T cell mediated anti-viral immunity

PloS one, 2014-02, Vol.9 (2), p.e90100-e90100

2014

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Soluble multi-trimeric TNF superfamily ligand adjuvants enhance immune responses to a HIV-1 Gag DNA vaccine

Vaccine, 2012-01, Vol.30 (4), p.691-702

2012

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Immunostimulatory combinations: designing the next generation of vaccine adjuvants

Journal of leukocyte biology, 2006-11, Vol.80 (5), p.1084-1102

2006

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Peripheral T Follicular Helper Cells Are the Major HIV Reservoir within Central Memory CD4 T Cells in Peripheral Blood from Chronically HIV-Infected Individuals on Combination Antiretroviral Therapy

Journal of virology, 2015-12, Vol.90 (6), p.2718-2728

2015

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Vaccination with a Fusion Protein That Introduces HIV-1 Gag Antigen into a Multitrimer CD40L Construct Results in Enhanced CD8+ T Cell Responses and Protection from Viral Challenge by Vaccinia-Gag

Journal of Virology, 2014-02, Vol.88 (3), p.1492-1501

2014

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Multimeric Soluble CD40 Ligand and GITR Ligand as Adjuvants for Human Immunodeficiency Virus DNA Vaccines

Journal of Virology, 2006-02, Vol.80 (4), p.1762-1772

2006

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Enhancement of the priming efficacy of DNA vaccines encoding dendritic cell-targeted antigens by synergistic toll-like receptor ligands

BMC immunology, 2009-08, Vol.10 (1), p.43-43, Article 43

2009

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EBV LMP1, a viral mimic of CD40, activates dendritic cells and functions as a molecular adjuvant when incorporated into an HIV vaccine

Journal of leukocyte biology, 2011-08, Vol.90 (2), p.389-398

2011

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The adjuvancy of OX40 ligand (CD252) on an HIV-1 canarypox vaccine

Vaccine, 2009-08, Vol.27 (37), p.5077-5084

2009

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A therapeutic HIV-1 vaccine reduces markers of systemic immune activation and latent infection in patients under highly active antiretroviral therapy

Vaccine, 2020-06, Vol.38 (27), p.4336-4345

2020

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A Targeted and Adjuvanted Nanocarrier Lowers the Effective Dose of Liposomal Amphotericin B and Enhances Adaptive Immunity in Murine Cutaneous Leishmaniasis

The Journal of infectious diseases, 2013-12, Vol.208 (11), p.1914-1922

2013

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DNA vaccine molecular adjuvants SP-D-BAFF and SP-D-APRIL enhance anti-gp120 immune response and increase HIV-1 neutralizing antibody titers

Journal of virology, 2015-04, Vol.89 (8), p.4158-4169

2015

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Latent Membrane Protein 1 as a molecular adjuvant for single-cycle lentiviral vaccines

Retrovirology, 2011-05, Vol.8 (1), p.39-39, Article 39

2011

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ILT2 and ILT4 Drive Myeloid Suppression via Both Overlapping and Distinct Mechanisms

Cancer immunology research, 2024-05, Vol.12 (5), p.592

2024

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Design of vaccine adjuvants incorporating TNF superfamily ligands and TNF superfamily molecular mimics

Immunologic research, 2013-12, Vol.57 (1-3), p.303-310

2013

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Design of CD40 Agonists and Their Use in Growing B Cells for Cancer Immunotherapy

International Reviews of Immunology, 2012-08, Vol.31 (4), p.279-288

2012

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Mechanism of Action of NB2001 and NB2030, Novel Antibacterial Agents Activated by β-Lactamases

Antimicrobial Agents and Chemotherapy, 2004-02, Vol.48 (2), p.477-483

2004

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Macaque Multimeric Soluble CD40 Ligand and GITR Ligand Constructs Are Immunostimulatory Molecules In Vitro

Clinical and Vaccine Immunology, 2006-11, Vol.13 (11), p.1223-1230

2006

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Preclinical evaluation of HIV-1 therapeutic ex vivo dendritic cell vaccines expressing consensus Gag antigens and conserved Gag epitopes

Vaccine, 2011-03, Vol.29 (11), p.2110-2119

2011

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CD40L expressed from the canarypox vector, ALVAC, can boost immunogenicity of HIV-1 canarypox vaccine in mice and enhance the in vitro expansion of viral specific CD8+ T cell memory responses from HIV-1-infected and HIV-1-uninfected individuals

Vaccine, 2008-07, Vol.26 (32), p.4062-4072

2008

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HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells

Constitutively Active MAVS Inhibits HIV-1 Replication via Type I Interferon Secretion and Induction of HIV-1 Restriction Factors

Epstein Barr virus Latent Membrane Protein-1 enhances dendritic cell therapy lymph node migration, activation, and IL-12 secretion

A multi-trimeric fusion of CD40L and gp100 tumor antigen activates dendritic cells and enhances survival in a B16-F10 melanoma DNA vaccine model

Nanoparticle-delivered multimeric soluble CD40L DNA combined with Toll-Like Receptor agonists as a treatment for melanoma

HIV-1 adenoviral vector vaccines expressing multi-trimeric BAFF and 4-1BBL enhance T cell mediated anti-viral immunity

Soluble multi-trimeric TNF superfamily ligand adjuvants enhance immune responses to a HIV-1 Gag DNA vaccine

Immunostimulatory combinations: designing the next generation of vaccine adjuvants

Peripheral T Follicular Helper Cells Are the Major HIV Reservoir within Central Memory CD4 T Cells in Peripheral Blood from Chronically HIV-Infected Individuals on Combination Antiretroviral Therapy

Vaccination with a Fusion Protein That Introduces HIV-1 Gag Antigen into a Multitrimer CD40L Construct Results in Enhanced CD8+ T Cell Responses and Protection from Viral Challenge by Vaccinia-Gag

Multimeric Soluble CD40 Ligand and GITR Ligand as Adjuvants for Human Immunodeficiency Virus DNA Vaccines

Enhancement of the priming efficacy of DNA vaccines encoding dendritic cell-targeted antigens by synergistic toll-like receptor ligands

EBV LMP1, a viral mimic of CD40, activates dendritic cells and functions as a molecular adjuvant when incorporated into an HIV vaccine

The adjuvancy of OX40 ligand (CD252) on an HIV-1 canarypox vaccine

A therapeutic HIV-1 vaccine reduces markers of systemic immune activation and latent infection in patients under highly active antiretroviral therapy

A Targeted and Adjuvanted Nanocarrier Lowers the Effective Dose of Liposomal Amphotericin B and Enhances Adaptive Immunity in Murine Cutaneous Leishmaniasis

DNA vaccine molecular adjuvants SP-D-BAFF and SP-D-APRIL enhance anti-gp120 immune response and increase HIV-1 neutralizing antibody titers

Latent Membrane Protein 1 as a molecular adjuvant for single-cycle lentiviral vaccines

ILT2 and ILT4 Drive Myeloid Suppression via Both Overlapping and Distinct Mechanisms

Design of vaccine adjuvants incorporating TNF superfamily ligands and TNF superfamily molecular mimics

Design of CD40 Agonists and Their Use in Growing B Cells for Cancer Immunotherapy

Mechanism of Action of NB2001 and NB2030, Novel Antibacterial Agents Activated by β-Lactamases

Macaque Multimeric Soluble CD40 Ligand and GITR Ligand Constructs Are Immunostimulatory Molecules In Vitro

Preclinical evaluation of HIV-1 therapeutic ex vivo dendritic cell vaccines expressing consensus Gag antigens and conserved Gag epitopes

CD40L expressed from the canarypox vector, ALVAC, can boost immunogenicity of HIV-1 canarypox vaccine in mice and enhance the in vitro expansion of viral specific CD8+ T cell memory responses from HIV-1-infected and HIV-1-uninfected individuals

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