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The P2X7 receptor channel: recent developments and the use of P2X7 antagonists in models of disease

Pharmacological reviews, 2014-07, Vol.66 (3), p.638-675

2014

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Revisiting the Idea That Amyloid-β Peptide Acts as an Agonist for P2X7

Frontiers in molecular neuroscience, 2020-09, Vol.13, p.166-166

2020

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P2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology

Frontiers in pharmacology, 2017-05, Vol.8, p.291-291

2017

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To Inhibit or Enhance? Is There a Benefit to Positive Allosteric Modulation of P2X Receptors?

Frontiers in pharmacology, 2020-05, Vol.11, p.627-627

2020

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Dynamic regulation of the P2X₄ receptor in alveolar macrophages by phagocytosis and classical activation

European journal of immunology, 2009-04, Vol.39 (4), p.986-995

2009

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Editorial: Neuroinflammation and Its Resolution: From Molecular Mechanisms to Therapeutic Perspectives

Frontiers in pharmacology, 2020-04, Vol.11, p.480-480

2020

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Probenecid blocks human P2X7 receptor-induced dye uptake via a pannexin-1 independent mechanism

PloS one, 2014-03, Vol.9 (3), p.e93058

2014

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Purinergic P2Y2 Receptors Induce Increased MCP-1/CCL2 Synthesis and Release from Rat Alveolar and Peritoneal Macrophages

The Journal of immunology (1950), 2007-11, Vol.179 (9), p.6016-6023

2007

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Understanding the role of P2X7 in affective disorders-are glial cells the major players?

Frontiers in cellular neuroscience, 2015-07, Vol.9, p.258-258

2015

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Recording P2X Receptors Using Whole-Cell Patch Clamp from Native Monocytes and Macrophages

Methods in molecular biology (Clifton, N.J.), 2020-01, Vol.2041, p.275

Stokes, Leanne

2020

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Genetics of the P2X7 receptor and human disease

Purinergic signalling, 2009-06, Vol.5 (2), p.257-262

2009

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Store-Operated Ca2+ Entry (SOCE) and Purinergic Receptor-Mediated Ca2+ Homeostasis in Murine bv2 Microglia Cells: Early Cellular Responses to ATP-Mediated Microglia Activation

Frontiers in molecular neuroscience, 2016-10, Vol.9, p.111-111

2016

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Bombesin receptor-targeted liposomes for enhanced delivery to lung cancer cells

Beilstein journal of nanotechnology, 2019, Vol.10 (1), p.2553-2562

2019

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P2X receptors: Insights from the study of the domestic dog

Neuropharmacology, 2023-02, Vol.224, p.109358, Article 109358

2023

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Rab5 regulates internalisation of P2X4 receptors and potentiation by ivermectin

Purinergic signalling, 2013-03, Vol.9 (1), p.113-121

Stokes, Leanne

2013

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Positive allosteric modulation of P2X7 promotes apoptotic cell death over lytic cell death responses in macrophages

Cell death & disease, 2019-11, Vol.10 (12), p.882-16, Article 882

2019

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P2X receptor antagonists and their potential as therapeutics: a patent review (2010-2021)

Expert opinion on therapeutic patents, 2022-07, Vol.32 (7), p.769-790

2022

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Bug Off Pain: An Educational Virtual Reality Game on Spider Venoms and Chronic Pain for Public Engagement

Journal of chemical education, 2019-07, Vol.96 (7), p.1486-1490

2019

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Insights into the Structure-Activity Relationship of Glycosides as Positive Allosteric Modulators Acting on P2X7 Receptors

Molecular pharmacology, 2021-02, Vol.99 (2), p.163-174

2021

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Development of High-Throughput Fluorescent-Based Screens to Accelerate Discovery of P2X Inhibitors from Animal Venoms

Journal of natural products (Washington, D.C.), 2019-09, Vol.82 (9), p.2559-2567

2019

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Rac1 plays a role in CXCL12 but not CCL3-induced chemotaxis and Rac1 GEF inhibitor NSC23766 has off target effects on CXCR4

Cellular signalling, 2018-01, Vol.42, p.88-96

2018

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Methods for studying P2X4 receptor ion channels in immune cells

Journal of immunological methods, 2024-03, Vol.526, p.113626-113626, Article 113626

2024

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Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7

Scientific reports, 2019-03, Vol.9 (1), p.3231-3231, Article 3231

2019

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Two haplotypes of the P2X₇ receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1β secretion

The FASEB journal, 2010-08, Vol.24 (8), p.2916-2927

2010

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Ginsenosides Act As Positive Modulators of P2X4 Receptors

Molecular pharmacology, 2019-02, Vol.95 (2), p.210-221

2019

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The P2X7 receptor channel: recent developments and the use of P2X7 antagonists in models of disease

Revisiting the Idea That Amyloid-β Peptide Acts as an Agonist for P2X7

P2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology

To Inhibit or Enhance? Is There a Benefit to Positive Allosteric Modulation of P2X Receptors?

Dynamic regulation of the P2X₄ receptor in alveolar macrophages by phagocytosis and classical activation

Editorial: Neuroinflammation and Its Resolution: From Molecular Mechanisms to Therapeutic Perspectives

Probenecid blocks human P2X7 receptor-induced dye uptake via a pannexin-1 independent mechanism

Purinergic P2Y2 Receptors Induce Increased MCP-1/CCL2 Synthesis and Release from Rat Alveolar and Peritoneal Macrophages

Understanding the role of P2X7 in affective disorders-are glial cells the major players?

Recording P2X Receptors Using Whole-Cell Patch Clamp from Native Monocytes and Macrophages

Genetics of the P2X7 receptor and human disease

Store-Operated Ca2+ Entry (SOCE) and Purinergic Receptor-Mediated Ca2+ Homeostasis in Murine bv2 Microglia Cells: Early Cellular Responses to ATP-Mediated Microglia Activation

Bombesin receptor-targeted liposomes for enhanced delivery to lung cancer cells

P2X receptors: Insights from the study of the domestic dog

Rab5 regulates internalisation of P2X4 receptors and potentiation by ivermectin

Positive allosteric modulation of P2X7 promotes apoptotic cell death over lytic cell death responses in macrophages

P2X receptor antagonists and their potential as therapeutics: a patent review (2010-2021)

Bug Off Pain: An Educational Virtual Reality Game on Spider Venoms and Chronic Pain for Public Engagement

Insights into the Structure-Activity Relationship of Glycosides as Positive Allosteric Modulators Acting on P2X7 Receptors

Development of High-Throughput Fluorescent-Based Screens to Accelerate Discovery of P2X Inhibitors from Animal Venoms

Rac1 plays a role in CXCL12 but not CCL3-induced chemotaxis and Rac1 GEF inhibitor NSC23766 has off target effects on CXCR4

Methods for studying P2X4 receptor ion channels in immune cells

Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7

Two haplotypes of the P2X₇ receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1β secretion

Ginsenosides Act As Positive Modulators of P2X4 Receptors

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