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Lysosomal Proteases and Their Inhibitors

International journal of molecular sciences, 2024-09, Vol.25 (18), p.10070

2024

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Cysteine cathepsins: From structure, function and regulation to new frontiers

Biochimica et biophysica acta, 2012-01, Vol.1824 (1), p.68-88

2012

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The Role of Cysteine Protease Cathepsins B, H, C, and X/Z in Neurodegenerative Diseases and Cancer

International journal of molecular sciences, 2023-11, Vol.24 (21), p.15613

2023

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Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in mice

Aging cell, 2019-02, Vol.18 (1), p.e12856-n/a

2019

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Glucosamine prevents polarization of cytotoxic granules in NK-92 cells by disturbing FOXO1/ERK/paxillin phosphorylation

PloS one, 2018-07, Vol.13 (7), p.e0200757-e0200757

2018

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Cysteine Cathepsins Trigger Caspase-dependent Cell Death through Cleavage of Bid and Antiapoptotic Bcl-2 Homologues

The Journal of biological chemistry, 2008-07, Vol.283 (27), p.19140-19150

2008

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Prediction of Transmembrane Regions, Cholesterol, and Ganglioside Binding Sites in Amyloid-Forming Proteins Indicate Potential for Amyloid Pore Formation

Frontiers in molecular neuroscience, 2021-02, Vol.14, p.619496

2021

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Lysosomal cysteine cathepsins: signaling pathways in apoptosis

Biological chemistry, 2007-06, Vol.388 (6), p.555-560

2007

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Lysosomal cathepsins and their regulation in aging and neurodegeneration

Ageing research reviews, 2016-12, Vol.32, p.22-37

2016

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Autophagy in protists

Autophagy, 2011-02, Vol.7 (2), p.127-158

2011

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Mechanisms of amyloid fibril formation - focus on domain-swapping

The FEBS journal, 2011-07, Vol.278 (13), p.2263-2282

2011

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Proline Residues as Switches in Conformational Changes Leading to Amyloid Fibril Formation

International journal of molecular sciences, 2017-03, Vol.18 (3), p.549-549

2017

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Protease signalling in cell death: caspases versus cysteine cathepsins

FEBS letters, 2007-06, Vol.581 (15), p.2761-2767

2007

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Lysosomes and lysosomal cathepsins in cell death

Biochimica et biophysica acta, 2012-01, Vol.1824 (1), p.22-33

2012

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The major cysteine proteinase of Trypanosoma cruzi: a valid target for chemotherapy of Chagas disease

Current pharmaceutical design, 2001-08, Vol.7 (12), p.1143-1156

2001

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The Novel Bovine Serpin Endopin 2C Demonstrates Selective Inhibition of the Cysteine Protease Cathepsin L Compared to the Serine Protease Elastase, in Cross-Class Inhibition

Biochemistry (Easton), 2005-05, Vol.44 (21), p.7757-7767

2005

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Cystatins: biochemical and structural properties, and medical relevance

Frontiers in bioscience, 2008-05, Vol.13 (13), p.5406

2008

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Human cathepsin X/Z is a biologically active homodimer

Biochimica et biophysica acta. Proteins and proteomics, 2021-02, Vol.1869 (2), p.140567-140567, Article 140567

2021

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Menadione‐induced apoptosis in U937 cells involves Bid cleavage and stefin B degradation

Journal of cellular biochemistry, 2019-06, Vol.120 (6), p.10662-10669

2019

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Tumor Necrosis Factor‐α Induced Apoptosis in U937 Cells Promotes Cathepsin D‐Independent Stefin B Degradation

Journal of cellular biochemistry, 2017-12, Vol.118 (12), p.4813-4820

2017

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A structural network associated with the kallikrein-kinin and renin-angiotensin systems

Biological chemistry, 2010-04, Vol.391 (4), p.443-454

2010

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A Role for Stefin B (Cystatin B) in Inflammation and Endotoxemia

The Journal of biological chemistry, 2014-11, Vol.289 (46), p.31736-31750

2014

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Characteristics, Structure, and Biological Role of Stefins (type-1 cystatins) of Human, Mammal, and Parasite Origin

Acta chimica Slovenica, 2019-02, Vol.66 (1), p.5-17

2019

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Fast profiling of protease specificity reveals similar substrate specificities for cathepsins K, L and S

Proteomics (Weinheim), 2015-07, Vol.15 (14), p.2479-2490

2015

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Lysosomal Cysteine Proteases: Structural Features and their Role in Apoptosis

IUBMB life, 2005-04, Vol.57 (4‐5), p.347-353

2005

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Lysosomal Proteases and Their Inhibitors

Cysteine cathepsins: From structure, function and regulation to new frontiers

The Role of Cysteine Protease Cathepsins B, H, C, and X/Z in Neurodegenerative Diseases and Cancer

Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in mice

Glucosamine prevents polarization of cytotoxic granules in NK-92 cells by disturbing FOXO1/ERK/paxillin phosphorylation

Cysteine Cathepsins Trigger Caspase-dependent Cell Death through Cleavage of Bid and Antiapoptotic Bcl-2 Homologues

Prediction of Transmembrane Regions, Cholesterol, and Ganglioside Binding Sites in Amyloid-Forming Proteins Indicate Potential for Amyloid Pore Formation

Lysosomal cysteine cathepsins: signaling pathways in apoptosis

Lysosomal cathepsins and their regulation in aging and neurodegeneration

Autophagy in protists

Mechanisms of amyloid fibril formation - focus on domain-swapping

Proline Residues as Switches in Conformational Changes Leading to Amyloid Fibril Formation

Protease signalling in cell death: caspases versus cysteine cathepsins

Lysosomes and lysosomal cathepsins in cell death

The major cysteine proteinase of Trypanosoma cruzi: a valid target for chemotherapy of Chagas disease

The Novel Bovine Serpin Endopin 2C Demonstrates Selective Inhibition of the Cysteine Protease Cathepsin L Compared to the Serine Protease Elastase, in Cross-Class Inhibition

Cystatins: biochemical and structural properties, and medical relevance

Human cathepsin X/Z is a biologically active homodimer

Menadione‐induced apoptosis in U937 cells involves Bid cleavage and stefin B degradation

Tumor Necrosis Factor‐α Induced Apoptosis in U937 Cells Promotes Cathepsin D‐Independent Stefin B Degradation

A structural network associated with the kallikrein-kinin and renin-angiotensin systems

A Role for Stefin B (Cystatin B) in Inflammation and Endotoxemia

Characteristics, Structure, and Biological Role of Stefins (type-1 cystatins) of Human, Mammal, and Parasite Origin

Fast profiling of protease specificity reveals similar substrate specificities for cathepsins K, L and S

Lysosomal Cysteine Proteases: Structural Features and their Role in Apoptosis

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