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Renal Transporters in Drug Development

Annual review of pharmacology and toxicology, 2013-01, Vol.53 (1), p.503-529

2013

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Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.890-899

2018

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Clinical Pharmacokinetics in Kidney Disease: Fundamental Principles

Clinical journal of the American Society of Nephrology, 2018-07, Vol.13 (7), p.1085-1095

2018

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Population Pharmacokinetic Models of Tacrolimus in Adult Transplant Recipients: A Systematic Review

Clinical pharmacokinetics, 2020-11, Vol.59 (11), p.1357-1392

2020

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Comment on “Population Pharmacokinetics of Total and Unbound Isavuconazole in Critically Ill Patients: Implications for Adaptive Dosing Strategies” and “High Variability in Isavuconazole Unbound Fraction in Clinical Practice: A Call to Reconsider Pharmacokinetic/Pharmacodynamic Targets and Breakpoints”

Clinical pharmacokinetics, 2024-05, Vol.63 (5), p.731-733

2024

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Predicting early bactericidal activity using pre-clinical data for tuberculosis drugs: a platform for model-informed drug discovery and development

The European respiratory journal, 2023-08, Vol.62 (2), p.2301108

2023

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Targeted disruption of organic cation transporter 3 attenuates the pharmacologic response to metformin

Molecular pharmacology, 2015-07, Vol.88 (1), p.75-83

2015

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Clinical Pharmacokinetics in Kidney Disease: Application to Rational Design of Dosing Regimens

Clinical journal of the American Society of Nephrology, 2018-08, Vol.13 (8), p.1254-1263

2018

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A framework for understanding sources of bias in medication adherence research

British journal of clinical pharmacology, 2023-11, Vol.89 (11), p.3444-3453

2023

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Potential Safety Issues with Use of Sodium-Glucose Cotransporter 2 Inhibitors, Particularly in People with Type 2 Diabetes and Chronic Kidney Disease

Drug safety, 2020-12, Vol.43 (12), p.1211-1221

2020

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A Model Averaging/Selection Approach Improves the Predictive Performance of Model‐Informed Precision Dosing: Vancomycin as a Case Study

Clinical pharmacology and therapeutics, 2021-01, Vol.109 (1), p.175-183

2021

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Barriers and opportunities for the clinical implementation of therapeutic drug monitoring in oncology

British journal of clinical pharmacology, 2021-02, Vol.87 (2), p.227-236

2021

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Prescribing of SGLT2 inhibitors in primary care: A qualitative study of General Practitioners and Endocrinologists

Diabetes research and clinical practice, 2021-10, Vol.180, p.109036-109036, Article 109036

2021

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Insights into the poor prognosis of allopurinol-induced severe cutaneous adverse reactions: the impact of renal insufficiency, high plasma levels of oxypurinol and granulysin

Annals of the rheumatic diseases, 2015-12, Vol.74 (12), p.2157-2164

2015

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Economic evaluations of therapeutic drug monitoring interventions in acute hospital‐based settings: A systematic review

British journal of clinical pharmacology, 2024-07, Vol.90 (9), p.2038-2066

2024

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Evaluation of published population pharmacokinetic models to inform tacrolimus dosing in adult heart transplant recipients

British journal of clinical pharmacology, 2022-02, Vol.88 (4), p.1751-1772

2022

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Analytical and Non-Analytical Variation May Lead to Inappropriate Antimicrobial Dosing in Neonates: An In Silico Study

Clinical chemistry (Baltimore, Md.), 2023-06, Vol.69 (6), p.637-648

2023

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Persistence with urate‐lowering therapy in Australia: A longitudinal analysis of allopurinol prescriptions

British journal of clinical pharmacology, 2022-11, Vol.88 (11), p.4894-4901

2022

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Voriconazole: an audit of hospital-based dosing and monitoring and evaluation of the predictive performance of a dose-prediction software package

Journal of antimicrobial chemotherapy, 2020-07, Vol.75 (7), p.1981-1984

2020

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Optimizing adherence to allopurinol for gout: patients' perspectives

British journal of clinical pharmacology, 2023-07, Vol.89 (7), p.1978-1991

2023

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The Influence of a Therapeutic Drug Monitoring Service on Vancomycin-Associated Nephrotoxicity

Journal of clinical pharmacology, 2024-01, Vol.64 (1), p.19-29

2024

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Adaptation of a population pharmacokinetic model to inform tacrolimus therapy in heart transplant recipients

British journal of clinical pharmacology, 2023-03, Vol.89 (3), p.1162-1175

2023

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Would they trust it? An exploration of psychosocial and environmental factors affecting prescriber acceptance of computerised dose‐recommendation software

British journal of clinical pharmacology, 2021-03, Vol.87 (3), p.1215-1233

2021

Volltextzugriff (PDF)

Blood, dose recommendation reports and phone calls: Experiences of a therapeutic drug monitoring advisory service for vancomycin

British journal of clinical pharmacology, 2023-06, Vol.89 (6), p.1896-1902

2023

Volltextzugriff (PDF)

Tacrolimus Therapy in Adult Heart Transplant Recipients: Evaluation of a Bayesian Forecasting Software

Therapeutic drug monitoring, 2021-12, Vol.43 (6), p.736

2021

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Renal Transporters in Drug Development

Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance

Clinical Pharmacokinetics in Kidney Disease: Fundamental Principles

Population Pharmacokinetic Models of Tacrolimus in Adult Transplant Recipients: A Systematic Review

Predicting early bactericidal activity using pre-clinical data for tuberculosis drugs: a platform for model-informed drug discovery and development

Targeted disruption of organic cation transporter 3 attenuates the pharmacologic response to metformin

Clinical Pharmacokinetics in Kidney Disease: Application to Rational Design of Dosing Regimens

A framework for understanding sources of bias in medication adherence research

Potential Safety Issues with Use of Sodium-Glucose Cotransporter 2 Inhibitors, Particularly in People with Type 2 Diabetes and Chronic Kidney Disease

A Model Averaging/Selection Approach Improves the Predictive Performance of Model‐Informed Precision Dosing: Vancomycin as a Case Study

Barriers and opportunities for the clinical implementation of therapeutic drug monitoring in oncology

Prescribing of SGLT2 inhibitors in primary care: A qualitative study of General Practitioners and Endocrinologists

Insights into the poor prognosis of allopurinol-induced severe cutaneous adverse reactions: the impact of renal insufficiency, high plasma levels of oxypurinol and granulysin

Economic evaluations of therapeutic drug monitoring interventions in acute hospital‐based settings: A systematic review

Evaluation of published population pharmacokinetic models to inform tacrolimus dosing in adult heart transplant recipients

Analytical and Non-Analytical Variation May Lead to Inappropriate Antimicrobial Dosing in Neonates: An In Silico Study

Persistence with urate‐lowering therapy in Australia: A longitudinal analysis of allopurinol prescriptions

Voriconazole: an audit of hospital-based dosing and monitoring and evaluation of the predictive performance of a dose-prediction software package

Optimizing adherence to allopurinol for gout: patients' perspectives

The Influence of a Therapeutic Drug Monitoring Service on Vancomycin-Associated Nephrotoxicity

Adaptation of a population pharmacokinetic model to inform tacrolimus therapy in heart transplant recipients

Would they trust it? An exploration of psychosocial and environmental factors affecting prescriber acceptance of computerised dose‐recommendation software

Blood, dose recommendation reports and phone calls: Experiences of a therapeutic drug monitoring advisory service for vancomycin

Tacrolimus Therapy in Adult Heart Transplant Recipients: Evaluation of a Bayesian Forecasting Software

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