UB Paderborn / Katalog / Suche / in CDI

EMD 1214063 and EMD 1204831 Constitute a New Class of Potent and Highly Selective c-Met Inhibitors

Clinical cancer research, 2013-06, Vol.19 (11), p.2941-2951

2013

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An Oxidation-Labile Traceless Linker for Solid-Phase Synthesis

Angewandte Chemie (International ed.), 1999-04, Vol.38 (8), p.1073-1077

1999

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Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors

Bioorganic & medicinal chemistry letters, 2015-04, Vol.25 (7), p.1597-1602

2015

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Multistep Solid-Phase Synthesis of an Antibiotic and Receptor Tyrosine Kinase Inhibitors Using the Traceless Phenylhydrazide Linker

Chemistry : a European journal, 2003-07, Vol.9 (14), p.3282-3291

2003

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Abstract 1787: The c-Met inhibitors EMD 1214063 and EMD 1204831 are effective in combination with EGFR and VEGF inhibitors in NSCLC models

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.1787-1787

2012

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Design and synthesis of isoquinolines and benzimidazoles as RAF kinase inhibitors

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (8), p.2264-2269

2011

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Abstract 3025: Discovery of preclinical development candidate inhibitors of the mediator complex-associated kinases CDK8 and CDK19 and evaluation of their therapeutic potential

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.3025-3025

2016

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Development of the Traceless Phenylhydrazide Linker for Solid-Phase Synthesis

Chemistry : a European journal, 2003-07, Vol.9 (14), p.3270-3281

2003

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Abstract 2786: Identification and preclinical characterization of EMD 1204831 – A selective c-Met kinase inhibitor in clinical phase 1

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.2786-2786

2011

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Development of new acid-functionalized resins for combinatorial synthesis on solid supportsElectronic supplementary information (ESI) available: experimental section. See http://www.rsc.org/suppdata/cc/b2/b204423d

Chemical communications (Cambridge, England), 2002-07 (16), p.1748-1749

2002

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Traceless Solid-Phase Synthesis of 2-Aminothiazoles: Receptor Tyrosine Kinase Inhibitors with Dual Selectivity for Tie-2 and VEGFR-2

Angewandte Chemie (International ed.), 2002-12, Vol.41 (24), p.4757-4761

2002

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Abstract 3622: Preclinical characterization of EMD1214063, a potent and highly selective inhibitor of the c-Met kinase in Phase I clinical trials

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.3622-3622

2010

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Abstract 5777: EMD 1214063, an exquisitely selective c-Met kinase inhibitor in clinical phase 1

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.5777-5777

2010

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Festphasensynthese von 2-Aminothiazolen unter Verwendung des spurlosen Hydrazid-Ankers: Rezeptortyrosinkinase-Inhibitoren mit dualer Selektivität für Tie-2 und VEGFR-2

Angewandte Chemie, 2002-12, Vol.114 (24), p.4951-4955

2002

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Development of new acid-functionalized resins for combinatorial synthesis on solid supports

Chemical communications (Cambridge, England), 2002-08 (16), p.1748-1749

2002

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Abstract B252: Identification of a new class of highly potent and selective c-Met kinase inhibitors

Molecular cancer therapeutics, 2009-12, Vol.8 (12_Supplement), p.B252-B252

2009

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Syntheses of Analogues of the Insect Neuropeptide Proctolin Containing an Oxazole Ring as an Amide Bond Replacement

Organic letters, 2001-11, Vol.3 (22), p.3427-3430

2001

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Festphasensynthese von 2‐Aminothiazolen unter Verwendung des spurlosen Hydrazid‐Ankers: Rezeptortyrosinkinase‐Inhibitoren mit dualer Selektivität für Tie‐2 und VEGFR‐2

Angewandte Chemie, 2002-12, Vol.114 (24), p.4951-4955

2002

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Syntheses of depsipeptide analogues of the insect neuropeptide proctolin

Bioorganic & medicinal chemistry letters, 2002-06, Vol.12 (12), p.1625-1628

2002

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Ein oxidationslabiler ,,spurloser"︁ Anker für die Festphasensynthese

Angewandte Chemie, 1999-04, Vol.111 (8), p.1142-1145

1999

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Ein oxidationslabiler „spurloser”︁ Anker für die Festphasensynthese

Angewandte Chemie, 1999-04, Vol.111 (8), p.1142-1145

1999

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Syntheses of Depsipeptide Analogues of the Insect Neuropeptide Proctolin

ChemInform, 2002-10, Vol.33 (40), p.191-191

2002

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ChemInform Abstract: Syntheses of Analogues of the Insect Neuropeptide Proctolin Containing an Oxazole Ring as an Amide Bond Replacement

ChemInform, 2002-03, Vol.33 (11), p.no-no

2002

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EMD 1214063 and EMD 1204831 Constitute a New Class of Potent and Highly Selective c-Met Inhibitors

Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19

Discovery of Potent, Orally Bioavailable, Small-Molecule Inhibitors of WNT Signaling from a Cell-Based Pathway Screen

An Oxidation-Labile Traceless Linker for Solid-Phase Synthesis

Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors

Multistep Solid-Phase Synthesis of an Antibiotic and Receptor Tyrosine Kinase Inhibitors Using the Traceless Phenylhydrazide Linker

Abstract 1787: The c-Met inhibitors EMD 1214063 and EMD 1204831 are effective in combination with EGFR and VEGF inhibitors in NSCLC models

Design and synthesis of isoquinolines and benzimidazoles as RAF kinase inhibitors

Abstract 3025: Discovery of preclinical development candidate inhibitors of the mediator complex-associated kinases CDK8 and CDK19 and evaluation of their therapeutic potential

Development of the Traceless Phenylhydrazide Linker for Solid-Phase Synthesis

Abstract 2786: Identification and preclinical characterization of EMD 1204831 – A selective c-Met kinase inhibitor in clinical phase 1

Development of new acid-functionalized resins for combinatorial synthesis on solid supportsElectronic supplementary information (ESI) available: experimental section. See http://www.rsc.org/suppdata/cc/b2/b204423d

Traceless Solid-Phase Synthesis of 2-Aminothiazoles: Receptor Tyrosine Kinase Inhibitors with Dual Selectivity for Tie-2 and VEGFR-2

Abstract 3622: Preclinical characterization of EMD1214063, a potent and highly selective inhibitor of the c-Met kinase in Phase I clinical trials

Abstract 5777: EMD 1214063, an exquisitely selective c-Met kinase inhibitor in clinical phase 1

Festphasensynthese von 2-Aminothiazolen unter Verwendung des spurlosen Hydrazid-Ankers: Rezeptortyrosinkinase-Inhibitoren mit dualer Selektivität für Tie-2 und VEGFR-2

Development of new acid-functionalized resins for combinatorial synthesis on solid supports

Abstract B252: Identification of a new class of highly potent and selective c-Met kinase inhibitors

Syntheses of Analogues of the Insect Neuropeptide Proctolin Containing an Oxazole Ring as an Amide Bond Replacement

Festphasensynthese von 2‐Aminothiazolen unter Verwendung des spurlosen Hydrazid‐Ankers: Rezeptortyrosinkinase‐Inhibitoren mit dualer Selektivität für Tie‐2 und VEGFR‐2

Syntheses of depsipeptide analogues of the insect neuropeptide proctolin

Ein oxidationslabiler ,,spurloser"︁ Anker für die Festphasensynthese

Ein oxidationslabiler „spurloser”︁ Anker für die Festphasensynthese

Syntheses of Depsipeptide Analogues of the Insect Neuropeptide Proctolin

ChemInform Abstract: Syntheses of Analogues of the Insect Neuropeptide Proctolin Containing an Oxazole Ring as an Amide Bond Replacement

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