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Characterisation of a smoke/ aerosol exposure in vitro system (SAEIVS) for delivery of complex mixtures directly to cells at the air‐liquid interface

Journal of applied toxicology, 2023-07, Vol.43 (7), p.1050-1063

2023

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Use of quantitative in vitro to in vivo extrapolation (QIVIVE) for the assessment of non-combustible next-generation product aerosols

Frontiers in toxicology, 2024-04, Vol.6, p.1373325-1373325

2024

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Multi-endpoint analysis of human 3D airway epithelium following repeated exposure to whole electronic vapor product aerosol or cigarette smoke

Current research in toxicology, 2021-01, Vol.2, p.99-115

2021

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The use of human induced pluripotent stem cells to screen for developmental toxicity potential indicates reduced potential for non-combusted products, when compared to cigarettes

Current research in toxicology, 2020-06, Vol.1, p.161-173

2020

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Use of a rapid human primary cell-based disease screening model, to compare next generation products to combustible cigarettes

Current research in toxicology, 2021-01, Vol.2, p.309-321

2021

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Meiotic telomere clustering requires actin for its formation and cohesin for its resolution

The Journal of cell biology, 2005-07, Vol.170 (2), p.213-223

2005

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Optimisation of an in vitro human cardiovascular model on-a-chip for toxicological assessment of nicotine delivery products

Frontiers in toxicology, 2024-06, Vol.6, p.1395670

2024

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Twenty-eight day repeated exposure of human 3D bronchial epithelial model to heated tobacco aerosols indicates decreased toxicological responses compared to cigarette smoke

Frontiers in toxicology, 2023-02, Vol.5, p.1076752-1076752

2023

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Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Predict the Cardiotoxicity Potential of Next Generation Nicotine Products

Frontiers in toxicology, 2022-02, Vol.4, p.747508

2022

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Meiotic Telomere Protein Ndj1p Is Required for Meiosis-Specific Telomere Distribution, Bouquet Formation and Efficient Homologue Pairing

The Journal of cell biology, 2000-10, Vol.151 (1), p.95-106

2000

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An interlaboratory in vitro aerosol exposure system reference study

Toxicology research and application, 2021-01, Vol.5

2021

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Absence of yKu/Hdf1 but not myosin-like proteins alters chromosome dynamics during prophase I in yeast

Differentiation (London), 2008, Vol.76 (1), p.91-98

2008

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High Content Screening in NHBE cells shows significantly reduced biological activity of flavoured e-liquids, when compared to cigarette smoke condensate

Toxicology in vitro, 2019-08, Vol.58, p.86-96

2019

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Increased ploidy and KAR3 and SIR3 disruption alter the dynamics of meiotic chromosomes and telomeres

Journal of cell science, 2003-06, Vol.116 (Pt 12), p.2431-2442

2003

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Multiple endpoint in vitro toxicity assessment of a prototype heated tobacco product indicates substantially reduced effects compared to those of combustible cigarette

Toxicology in vitro, 2023-02, Vol.86, p.105510, Article 105510

2023

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The in vitro ToxTracker and Aneugen Clastogen Evaluation extension assay as a tool in the assessment of relative genotoxic potential of e-liquids and their aerosols

Mutagenesis, 2021-05, Vol.36 (2), p.129-142

2021

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Mainstream Smoke Chemistry and in Vitro and In Vivo Toxicity of the Reference Cigarettes 3R4F and 2R4F

Beiträge zur Tabakforschung international, 2012-02, Vol.25 (1), p.316-335

2012

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Preclinical Assessment of Tobacco-Free Nicotine Pouches Demonstrates Reduced In Vitro Toxicity Compared with Tobacco Snus and Combustible Cigarette Smoke

Applied in vitro toxicology, 2022-03, Vol.8 (1), p.24-35

2022

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Chemical Composition and In Vitro Toxicity Profile of a Pod-Based E-Cigarette Aerosol Compared to Cigarette Smoke

Applied in vitro toxicology, 2020-03, Vol.6 (1), p.11-41

2020

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Bouquet formation in budding yeast: initiation of recombination is not required for meiotic telomere clustering

Journal of cell science, 1999-03, Vol.112 ( Pt 5) (5), p.651-658

1999

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Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in yeast

Nature cell biology, 2002-03, Vol.4 (3), p.214-221

2002

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Automation of the in vitro micronucleus and chromosome aberration assay for the assessment of the genotoxicity of the particulate and gas-vapor phase of cigarette smoke

Toxicology mechanisms and methods, 2015-01, Vol.25 (4), p.320-333

2015

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Yeast nuclei display prominent centromere clustering that is reduced in nondividing cells and in meiotic prophase

The Journal of cell biology, 1998-04, Vol.141 (1), p.21-29

1998

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Wild-Type Levels of Spo11-Induced DSBs Are Required for Normal Single-Strand Resection during Meiosis

Molecular cell, 2002-04, Vol.9 (4), p.835-846

2002

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Set1- and Clb5-deficiencies disclose the differential regulation of centromere and telomere dynamics in Saccharomyces cerevisiae meiosis

Journal of cell science, 2005-11, Vol.118 (21), p.4985-4994

2005

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Saccharomyces Cerevisiae Proteins - Genetics
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Characterisation of a smoke/ aerosol exposure in vitro system (SAEIVS) for delivery of complex mixtures directly to cells at the air‐liquid interface

Use of quantitative in vitro to in vivo extrapolation (QIVIVE) for the assessment of non-combustible next-generation product aerosols

Multi-endpoint analysis of human 3D airway epithelium following repeated exposure to whole electronic vapor product aerosol or cigarette smoke

The use of human induced pluripotent stem cells to screen for developmental toxicity potential indicates reduced potential for non-combusted products, when compared to cigarettes

Use of a rapid human primary cell-based disease screening model, to compare next generation products to combustible cigarettes

Meiotic telomere clustering requires actin for its formation and cohesin for its resolution

Optimisation of an in vitro human cardiovascular model on-a-chip for toxicological assessment of nicotine delivery products

Twenty-eight day repeated exposure of human 3D bronchial epithelial model to heated tobacco aerosols indicates decreased toxicological responses compared to cigarette smoke

Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Predict the Cardiotoxicity Potential of Next Generation Nicotine Products

Meiotic Telomere Protein Ndj1p Is Required for Meiosis-Specific Telomere Distribution, Bouquet Formation and Efficient Homologue Pairing

An interlaboratory in vitro aerosol exposure system reference study

Absence of yKu/Hdf1 but not myosin-like proteins alters chromosome dynamics during prophase I in yeast

High Content Screening in NHBE cells shows significantly reduced biological activity of flavoured e-liquids, when compared to cigarette smoke condensate

Increased ploidy and KAR3 and SIR3 disruption alter the dynamics of meiotic chromosomes and telomeres

Multiple endpoint in vitro toxicity assessment of a prototype heated tobacco product indicates substantially reduced effects compared to those of combustible cigarette

The in vitro ToxTracker and Aneugen Clastogen Evaluation extension assay as a tool in the assessment of relative genotoxic potential of e-liquids and their aerosols

Mainstream Smoke Chemistry and in Vitro and In Vivo Toxicity of the Reference Cigarettes 3R4F and 2R4F

Preclinical Assessment of Tobacco-Free Nicotine Pouches Demonstrates Reduced In Vitro Toxicity Compared with Tobacco Snus and Combustible Cigarette Smoke

Chemical Composition and In Vitro Toxicity Profile of a Pod-Based E-Cigarette Aerosol Compared to Cigarette Smoke

Bouquet formation in budding yeast: initiation of recombination is not required for meiotic telomere clustering

Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in yeast

Automation of the in vitro micronucleus and chromosome aberration assay for the assessment of the genotoxicity of the particulate and gas-vapor phase of cigarette smoke

Yeast nuclei display prominent centromere clustering that is reduced in nondividing cells and in meiotic prophase

Wild-Type Levels of Spo11-Induced DSBs Are Required for Normal Single-Strand Resection during Meiosis

Set1- and Clb5-deficiencies disclose the differential regulation of centromere and telomere dynamics in Saccharomyces cerevisiae meiosis

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