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Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation

Frontiers in immunology, 2017-03, Vol.8, p.292-292

2017

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Exchange catalysis by tapasin exploits conserved and allele-specific features of MHC-I molecules

Nature communications, 2021-07, Vol.12 (1), p.4236-4236, Article 4236

2021

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Type 1 Diabetes and the HLA Region: Genetic Association Besides Classical HLA Class II Genes

Frontiers in genetics, 2021-06, Vol.12, p.683946-683946

2021

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MHC class II complexes sample intermediate states along the peptide exchange pathway

Nature communications, 2016-11, Vol.7 (1), p.13224-13224, Article 13224

2016

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Human leukocyte Antigen-DM polymorphisms in autoimmune diseases

Open biology, 2016-08, Vol.6 (8), p.160165

2016

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Bidirectional binding of invariant chain peptides to an MHC class II molecule

Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (51), p.22219-22224

2010

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The Na,K-ATPase acts upstream of phosphoinositide PI(4,5)P2 facilitating unconventional secretion of Fibroblast Growth Factor 2

Communications biology, 2020-03, Vol.3 (1), p.141-141, Article 141

2020

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Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein

The Journal of biological chemistry, 2008-11, Vol.283 (46), p.32024-32033

2008

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Major histocompatibility complex (MHC) class I and class II proteins: impact of polymorphism on antigen presentation

Current opinion in immunology, 2021-06, Vol.70, p.95-104

2021

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Proline-rich Sequence Recognition

Molecular & cellular proteomics, 2009-11, Vol.8 (11), p.2474-2486

2009

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Target Recognition in Tandem WW Domains: Complex Structures for Parallel and Antiparallel Ligand Orientation in h‑FBP21 Tandem WW

Journal of chemical information and modeling, 2022-12, Vol.62 (24), p.6586-6601

2022

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MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange

Nature chemical biology, 2023-10, Vol.19 (10), p.1196-1204

2023

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Kinetics, Thermodynamics, and Structural Effects of Quinoline-2-Carboxylates, Zinc-Binding Inhibitors of New Delhi Metallo-β-lactamase‑1 Re-sensitizing Multidrug-Resistant Bacteria for Carbapenems

Journal of medicinal chemistry, 2023-09, Vol.66 (17), p.11761-11791

2023

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Intrinsically Disordered Protein Ntr2 Modulates the Spliceosomal RNA Helicase Brr2

Biophysical journal, 2018-02, Vol.114 (4), p.788-799

2018

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Noninvasive Imaging of Human Immune Responses in a Human Xenograft Model of Graft-Versus-Host Disease

Journal of Nuclear Medicine, 2017-06, Vol.58 (6), p.1003-1008

2017

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HLA-DMA polymorphisms differentially affect MHC class II peptide loading

The Journal of immunology (1950), 2015-01, Vol.194 (2), p.803-816

2015

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Susceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with Peptide

The Journal of biological chemistry, 2014-08, Vol.289 (34), p.23449-23464

2014

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FBP21’s C-Terminal Domain Remains Dynamic When Wrapped around the c-Sec63 Unit of Brr2 Helicase

Biophysical journal, 2019-02, Vol.116 (3), p.406-418

2019

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A new role for FBP21 as regulator of Brr2 helicase activity

Nucleic acids research, 2017-07, Vol.45 (13), p.7922-7937

2017

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MHC Class II Complexes Sample Intermediate States along the Antigenic Peptide Exchange Pathway

Biophysical journal, 2018-02, Vol.114 (3), p.399a-399a

2018

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D120 and K152 within the PH Domain of T Cell Adapter SKAP55 Regulate Plasma Membrane Targeting of SKAP55 and LFA-1 Affinity Modulation in Human T Lymphocytes

Molecular and cellular biology, 2017-04, Vol.37 (7)

2017

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Exon Inclusion Modulates Conformational Plasticity and Autoinhibition of the Intersectin 1 SH3A Domain

Structure (London), 2019-06, Vol.27 (6), p.977-987.e5

2019

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Xenon-129 Biosensor for Monitoring MHC-Peptide Interactions

Angewandte Chemie (International ed.), 2009-05, Vol.48 (23), p.4142-4145

2009

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A peptide inhibitor of HIV-1 assembly in vitro

Nature structural & molecular biology, 2005-08, Vol.12 (8), p.671-677

2005

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Peptide Linkage to the α-Subunit of MHCII Creates a Stably Inverted Antigen Presentation Complex

Journal of molecular biology, 2012-10, Vol.423 (3), p.294-302

2012

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Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation

Exchange catalysis by tapasin exploits conserved and allele-specific features of MHC-I molecules

Type 1 Diabetes and the HLA Region: Genetic Association Besides Classical HLA Class II Genes

MHC class II complexes sample intermediate states along the peptide exchange pathway

Human leukocyte Antigen-DM polymorphisms in autoimmune diseases

Bidirectional binding of invariant chain peptides to an MHC class II molecule

The Na,K-ATPase acts upstream of phosphoinositide PI(4,5)P2 facilitating unconventional secretion of Fibroblast Growth Factor 2

Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein

Major histocompatibility complex (MHC) class I and class II proteins: impact of polymorphism on antigen presentation

Proline-rich Sequence Recognition

Target Recognition in Tandem WW Domains: Complex Structures for Parallel and Antiparallel Ligand Orientation in h‑FBP21 Tandem WW

MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange

Kinetics, Thermodynamics, and Structural Effects of Quinoline-2-Carboxylates, Zinc-Binding Inhibitors of New Delhi Metallo-β-lactamase‑1 Re-sensitizing Multidrug-Resistant Bacteria for Carbapenems

Intrinsically Disordered Protein Ntr2 Modulates the Spliceosomal RNA Helicase Brr2

Noninvasive Imaging of Human Immune Responses in a Human Xenograft Model of Graft-Versus-Host Disease

HLA-DMA polymorphisms differentially affect MHC class II peptide loading

Susceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with Peptide

FBP21’s C-Terminal Domain Remains Dynamic When Wrapped around the c-Sec63 Unit of Brr2 Helicase

A new role for FBP21 as regulator of Brr2 helicase activity

MHC Class II Complexes Sample Intermediate States along the Antigenic Peptide Exchange Pathway

D120 and K152 within the PH Domain of T Cell Adapter SKAP55 Regulate Plasma Membrane Targeting of SKAP55 and LFA-1 Affinity Modulation in Human T Lymphocytes

Exon Inclusion Modulates Conformational Plasticity and Autoinhibition of the Intersectin 1 SH3A Domain

Xenon-129 Biosensor for Monitoring MHC-Peptide Interactions

A peptide inhibitor of HIV-1 assembly in vitro

Peptide Linkage to the α-Subunit of MHCII Creates a Stably Inverted Antigen Presentation Complex

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