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Leveraging genetic diversity to identify small molecules that reverse mouse skeletal muscle insulin resistance

eLife, 2023-07, Vol.12

2023

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The metabolic consequences of ‘yo-yo’ dieting are markedly influenced by genetic diversity

International Journal of Obesity, 2024-08, Vol.48 (8), p.1170-1179

2024

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Dual Tracer Test to Measure Tissue-Specific Insulin Action in Individual Mice Identifies In Vivo Insulin Resistance Without Fasting Hyperinsulinemia

Diabetes (New York, N.Y.), 2024-03, Vol.73 (3), p.359-373

2024

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The genetic and dietary landscape of the muscle insulin signalling network

eLife, 2024-02, Vol.12

2024

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Improvement in prediction of coronary heart disease risk over conventional risk factors using SNPs identified in genome-wide association studies

PloS one, 2013-02, Vol.8 (2), p.e57310-e57310

2013

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Aspirin for prevention of cardiovascular events in a general population screened for a low ankle brachial index: a randomized controlled trial

JAMA : the journal of the American Medical Association, 2010-03, Vol.303 (9), p.841

2010

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A role for β‐catenin in diet‐induced skeletal muscle insulin resistance

Physiological reports, 2023-02, Vol.11 (4), p.e15536-n/a

2023

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Scottish smoke-free legislation and trends in smoking cessation

Addiction (Abingdon, England), 2008-11, Vol.103 (11), p.1888-1895

2008

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Systems-level analysis of insulin action in mouse strains provides insight into tissue- and pathway-specific interactions that drive insulin resistance

Cell metabolism, 2022-02, Vol.34 (2), p.227-239.e6

2022

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Untreated 24-h intraocular pressures measured with Goldmann applanation tonometry vs nighttime supine pressures with Perkins applanation tonometry

Eye (London), 2010-07, Vol.24 (7), p.1252-1258

2010

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Twenty-four-hour intraocular pressure and blood pressure levels with bimatoprost versus latanoprost in patients with normal-tension glaucoma

British journal of ophthalmology, 2008-09, Vol.92 (9), p.1227-1231

2008

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The clinical validity of the treatment satisfaction survey for intraocular pressure in ocular hypertensive and glaucoma patients

Eye (London), 2006-05, Vol.20 (5), p.583-590

2006

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β‐Catenin is required for optimal exercise‐ and contraction‐stimulated skeletal muscle glucose uptake

The Journal of physiology, 2021-08, Vol.599 (16), p.3897-3912

2021

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Twenty-four-hour intraocular pressure control with the travoprost/timolol maleate fixed combination compared with travoprost when both are dosed in the evening in primary open-angle glaucoma

British journal of ophthalmology, 2009-04, Vol.93 (4), p.481-485

2009

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Cost-effectiveness of latanoprost and timolol maleate for the treatment of glaucoma in Scandinavia and the United Kingdom, using a decision-analytic health economic model

Eye (London), 2009-01, Vol.23 (1), p.132-140

2009

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β-catenin regulates muscle glucose transport via actin remodelling and M-cadherin binding

Molecular metabolism (Germany), 2020-12, Vol.42, p.101091-101091, Article 101091

2020

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Sirtuin 1 is not required for contraction-stimulated glucose uptake in mouse skeletal muscle

Journal of applied physiology (1985), 2021-06, Vol.130 (6), p.1893-1902

2021

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Investigation of a Q Fever Outbreak in a Scottish Co‐Located Slaughterhouse and Cutting Plant

Zoonoses and public health, 2010-12, Vol.57 (7), p.493-498

2010

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24-h Intraocular pressure control with evening-dosed travoprost timolol, compared with latanoprost timolol, fixed combinations in exfoliative glaucoma

Eye (London), 2010-10, Vol.24 (10), p.1606-1613

2010

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Mitochondrial glycerol 3-phosphate facilitates bumblebee pre-flight thermogenesis

Scientific reports, 2017-10, Vol.7 (1), p.13107-7, Article 13107

2017

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α1-Antitrypsin A treatment attenuates neutrophil elastase accumulation and enhances insulin sensitivity in adipose tissue of mice fed a high-fat diet

American journal of physiology: endocrinology and metabolism, 2021-10, Vol.321 (4), p.E560-E570

2021

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Organic and inorganic selenium: II. Transfer efficiency from ewes to lambs1

Journal of animal science, 2012-02, Vol.90 (2), p.577-584

2012

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Second-line therapy with dorzolamide/timolol or latanoprost/timolol fixed combination versus adding dorzolamide/timolol fixed combination to latanoprost monotherapy

British journal of ophthalmology, 2008-11, Vol.92 (11), p.1498-1502

2008

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Intelligence and persisting with medication for two years: Analysis in a randomised controlled trial

Intelligence (Norwood), 2009-11, Vol.37 (6), p.607-612

2009

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Using clinical and genetic data to predict pulmonary hypertension in bronchopulmonary dysplasia

Acta Paediatrica, 2018-12, Vol.107 (12), p.2158-2164

2018

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Leveraging genetic diversity to identify small molecules that reverse mouse skeletal muscle insulin resistance

The metabolic consequences of ‘yo-yo’ dieting are markedly influenced by genetic diversity

Dual Tracer Test to Measure Tissue-Specific Insulin Action in Individual Mice Identifies In Vivo Insulin Resistance Without Fasting Hyperinsulinemia

The genetic and dietary landscape of the muscle insulin signalling network

Improvement in prediction of coronary heart disease risk over conventional risk factors using SNPs identified in genome-wide association studies

Aspirin for prevention of cardiovascular events in a general population screened for a low ankle brachial index: a randomized controlled trial

A role for β‐catenin in diet‐induced skeletal muscle insulin resistance

Scottish smoke-free legislation and trends in smoking cessation

Systems-level analysis of insulin action in mouse strains provides insight into tissue- and pathway-specific interactions that drive insulin resistance

Untreated 24-h intraocular pressures measured with Goldmann applanation tonometry vs nighttime supine pressures with Perkins applanation tonometry

Twenty-four-hour intraocular pressure and blood pressure levels with bimatoprost versus latanoprost in patients with normal-tension glaucoma

The clinical validity of the treatment satisfaction survey for intraocular pressure in ocular hypertensive and glaucoma patients

β‐Catenin is required for optimal exercise‐ and contraction‐stimulated skeletal muscle glucose uptake

Twenty-four-hour intraocular pressure control with the travoprost/timolol maleate fixed combination compared with travoprost when both are dosed in the evening in primary open-angle glaucoma

Cost-effectiveness of latanoprost and timolol maleate for the treatment of glaucoma in Scandinavia and the United Kingdom, using a decision-analytic health economic model

β-catenin regulates muscle glucose transport via actin remodelling and M-cadherin binding

Sirtuin 1 is not required for contraction-stimulated glucose uptake in mouse skeletal muscle

Investigation of a Q Fever Outbreak in a Scottish Co‐Located Slaughterhouse and Cutting Plant

24-h Intraocular pressure control with evening-dosed travoprost timolol, compared with latanoprost timolol, fixed combinations in exfoliative glaucoma

Mitochondrial glycerol 3-phosphate facilitates bumblebee pre-flight thermogenesis

α1-Antitrypsin A treatment attenuates neutrophil elastase accumulation and enhances insulin sensitivity in adipose tissue of mice fed a high-fat diet

Organic and inorganic selenium: II. Transfer efficiency from ewes to lambs1

Second-line therapy with dorzolamide/timolol or latanoprost/timolol fixed combination versus adding dorzolamide/timolol fixed combination to latanoprost monotherapy

Intelligence and persisting with medication for two years: Analysis in a randomised controlled trial

Using clinical and genetic data to predict pulmonary hypertension in bronchopulmonary dysplasia

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