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Studies of house dust mites can now fully embrace the “-omics” era

Journal of allergy and clinical immunology, 2015-02, Vol.135 (2), p.549-550

Stewart, Geoffrey A., PhD

2015

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House Dust Mite Allergens Induce Proinflammatory Cytokines from Respiratory Epithelial Cells: The Cysteine Protease Allergen, Der p 1, Activates Protease-Activated Receptor (PAR)-2 and Inactivates PAR-1

The Journal of immunology (1950), 2002-10, Vol.169 (8), p.4572-4578

2002

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Activation of Protease-Activated Receptor (PAR)-1, PAR-2, and PAR-4 Stimulates IL-6, IL-8, and Prostaglandin E2 Release from Human Respiratory Epithelial Cells

The Journal of immunology (1950), 2002-04, Vol.168 (7), p.3577-3585

2002

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Dermatophagoides pteronyssinus lytFM encoding an NlpC/P60 endopeptidase is also present in mite‐associated bacteria that express LytFM variants

FEBS open bio, 2017-09, Vol.7 (9), p.1267-1280

2017

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Dust Mite Proteolytic Allergens Induce Cytokine Release from Cultured Airway Epithelium

The Journal of immunology (1950), 1998-10, Vol.161 (7), p.3645-3651

1998

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Th2 polarization by Der p 1–pulsed monocyte-derived dendritic cells is due to the allergic status of the donors

Blood, 2001-08, Vol.98 (4), p.1135-1141

2001

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House dust mites possess a polymorphic, single domain putative peptidoglycan d,l endopeptidase belonging to the NlpC/P60 Superfamily

FEBS open bio, 2015-01, Vol.5 (1), p.813-823

2015

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Role of protease-activated receptors in airway function: a target for therapeutic intervention?

Pharmacology & therapeutics (Oxford), 2002-09, Vol.95 (3), p.239-257

2002

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Activation of protease‐activated receptors (PARs)‐1 and ‐2 promotes alpha‐smooth muscle actin expression and release of cytokines from human lung fibroblasts

Physiological reports, 2015-02, Vol.3 (2), p.e12295-n/a

2015

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Der p 1-pulsed myeloid and plasmacytoid dendritic cells from house dust mite-sensitized allergic patients dysregulate the T cell response

Journal of leukocyte biology, 2003-01, Vol.73 (1), p.91-99

2003

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Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions

The Journal of clinical investigation, 1999-07, Vol.104 (1), p.123-133

1999

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Class specific inhibition of house dust mite proteinases which cleave cell adhesion, induce cell death and which increase the permeability of lung epithelium

British journal of pharmacology, 1998-07, Vol.124 (6), p.1048-1059

1998

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Protease-activated receptors in human airways: Upregulation of PAR-2 in respiratory epithelium from patients with asthma

Journal of allergy and clinical immunology, 2001-11, Vol.108 (5), p.797-803

2001

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Skin-associated Bacillus, staphylococcal and micrococcal species from the house dust mite, Dermatophagoides pteronyssinus and bacteriolytic enzymes

Experimental & applied acarology, 2013-12, Vol.61 (4), p.431-447

2013

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Fibrin sealant promotes migration and proliferation of human articular chondrocytes: Possible involvement of thrombin and protease-activated receptors

International journal of molecular medicine, 2006-04, Vol.17 (4), p.551-558

2006

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Activation of the plasma kallikrein-kinin system on human lung epithelial cells

Biological chemistry, 2010-09, Vol.391 (9), p.1067-1077

2010

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Immunomodulatory effects of functionalised chalcones on pro-inflammatory cytokine release from lung epithelial cells

New journal of chemistry, 2009, Vol.33 (9), p.1869-1873

2009

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Altered expression and in vivo lung function of protease-activated receptors during influenza A virus infection in mice

American journal of physiology. Lung cellular and molecular physiology, 2004-02, Vol.286 (2), p.388-L398

2004

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Mesothelial cells activate the plasma kallikrein-kinin system during pleural inflammation

Biological chemistry, 2011-07, Vol.392 (7), p.633-642

2011

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Alveolar Macrophages Bind and Phagocytose Allergen- Containing Pollen Starch Granules Via C-Type Lectin and Integrin Receptors: Implications for Airway Inflammatory Disease

The Journal of immunology (1950), 2000-04, Vol.164 (7), p.3878-3886

2000

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Monocyte-derived dendritic cells exposed to Der p 1 allergen enhance the recruitment of Th2 cells: major involvement of the chemokines TARC/CCL17 and MDC/CCL22

European cytokine network (Montrouge), 2003-10, Vol.14 (4), p.219-228

2003

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Nitric oxide production by alveolar macrophages in response to house dust mite fecal pellets and the mite allergens, Der p 1 and Der p 2

Journal of allergy and clinical immunology, 2003-09, Vol.112 (3), p.531-537

2003

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Peptidase allergen Der p 1 initiates apoptosis of epithelial cells independently of tight junction proteolysis

Molecular membrane biology, 2003, Vol.20 (1), p.71-81

2003

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Oncostatin M synergises with house dust mite proteases to induce the production of PGE2 from cultured lung epithelial cells

British journal of pharmacology, 2000-10, Vol.131 (3), p.465-472

2000

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Dermatophagoides pteronyssinus lyt FM encoding an NlpC/P60 endopeptidase is also present in mite‐associated bacteria that express Lyt FM variants

FEBS open bio, 2017-09, Vol.7 (9), p.1267-1280

2017

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Studies of house dust mites can now fully embrace the “-omics” era

House Dust Mite Allergens Induce Proinflammatory Cytokines from Respiratory Epithelial Cells: The Cysteine Protease Allergen, Der p 1, Activates Protease-Activated Receptor (PAR)-2 and Inactivates PAR-1

Activation of Protease-Activated Receptor (PAR)-1, PAR-2, and PAR-4 Stimulates IL-6, IL-8, and Prostaglandin E2 Release from Human Respiratory Epithelial Cells

Dermatophagoides pteronyssinus lytFM encoding an NlpC/P60 endopeptidase is also present in mite‐associated bacteria that express LytFM variants

Dust Mite Proteolytic Allergens Induce Cytokine Release from Cultured Airway Epithelium

Th2 polarization by Der p 1–pulsed monocyte-derived dendritic cells is due to the allergic status of the donors

House dust mites possess a polymorphic, single domain putative peptidoglycan d,l endopeptidase belonging to the NlpC/P60 Superfamily

Role of protease-activated receptors in airway function: a target for therapeutic intervention?

Activation of protease‐activated receptors (PARs)‐1 and ‐2 promotes alpha‐smooth muscle actin expression and release of cytokines from human lung fibroblasts

Der p 1-pulsed myeloid and plasmacytoid dendritic cells from house dust mite-sensitized allergic patients dysregulate the T cell response

Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions

Class specific inhibition of house dust mite proteinases which cleave cell adhesion, induce cell death and which increase the permeability of lung epithelium

Protease-activated receptors in human airways: Upregulation of PAR-2 in respiratory epithelium from patients with asthma

Skin-associated Bacillus, staphylococcal and micrococcal species from the house dust mite, Dermatophagoides pteronyssinus and bacteriolytic enzymes

Fibrin sealant promotes migration and proliferation of human articular chondrocytes: Possible involvement of thrombin and protease-activated receptors

Activation of the plasma kallikrein-kinin system on human lung epithelial cells

Immunomodulatory effects of functionalised chalcones on pro-inflammatory cytokine release from lung epithelial cells

Altered expression and in vivo lung function of protease-activated receptors during influenza A virus infection in mice

Mesothelial cells activate the plasma kallikrein-kinin system during pleural inflammation

Alveolar Macrophages Bind and Phagocytose Allergen- Containing Pollen Starch Granules Via C-Type Lectin and Integrin Receptors: Implications for Airway Inflammatory Disease

Monocyte-derived dendritic cells exposed to Der p 1 allergen enhance the recruitment of Th2 cells: major involvement of the chemokines TARC/CCL17 and MDC/CCL22

Nitric oxide production by alveolar macrophages in response to house dust mite fecal pellets and the mite allergens, Der p 1 and Der p 2

Peptidase allergen Der p 1 initiates apoptosis of epithelial cells independently of tight junction proteolysis

Oncostatin M synergises with house dust mite proteases to induce the production of PGE2 from cultured lung epithelial cells

Dermatophagoides pteronyssinus lyt FM encoding an NlpC/P60 endopeptidase is also present in mite‐associated bacteria that express Lyt FM variants

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