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HGF/c-Met acts as an alternative angiogenic pathway in sunitinib-resistant tumors

Cancer research (Chicago, Ill.), 2010-12, Vol.70 (24), p.10090-10100

2010

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Discovery of (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a macrocyclic inhibitor of anaplastic lymphoma kinase (ALK) and c-ros oncogene 1 (ROS1) with preclinical brain exposure and broad-spectrum potency against ALK-resistant mutations

Journal of medicinal chemistry, 2014-06, Vol.57 (11), p.4720-4744

2014

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Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate (R)-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2H)-one (PF-06821497)

Journal of medicinal chemistry, 2018-02, Vol.61 (3), p.650-665

2018

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Characterization of Specific N -α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library

ACS medicinal chemistry letters, 2020-06, Vol.11 (6), p.1175-1184

2020

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Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation

Nature structural biology, 1999-02, Vol.6 (2), p.174-181

1999

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Incorporating anomalous scattering centres into macromolecules

Current opinion in structural biology, 1996-10, Vol.6 (5), p.611-616

1996

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Eukaryotic Methionyl Aminopeptidases: Two Classes of Cobalt-Dependent Enzymes

Proceedings of the National Academy of Sciences - PNAS, 1995-08, Vol.92 (17), p.7714-7718

1995

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Analysis of protein modifications: recent advances in detection, characterization and mapping

Current opinion in biotechnology, 1994, Vol.5 (1), p.85-93

1994

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A Mouse Amidase Specific for N-terminal Asparagine

The Journal of biological chemistry, 1996-11, Vol.271 (45), p.28521-28532

1996

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Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate (R)‑5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2H)‑one (PF-06821497)

Journal of medicinal chemistry, 2018-02, Vol.61 (3), p.650-665

2018

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A mouse amidase specific for N-terminal asparagine. The gene, the enzyme, and their function in the N-end rule pathway

The Journal of biological chemistry, 1996-11, Vol.271 (45), p.28521-28532

1996

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Discovery of (10R)‑7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H‑8,4-(metheno)pyrazolo[4,3‑h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations

Journal of medicinal chemistry, 2014-06, Vol.57 (11), p.4720-4744

2014

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The Sequence of Porcine Protein NH2-terminal Asparagine Amidohydrolase

The Journal of biological chemistry, 1995-01, Vol.270 (1), p.25-28

1995

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The Sequence of Porcine Protein NH-terminal Asparagine Amidohydrolase

The Journal of biological chemistry, 1995-01, Vol.270 (1), p.25

1995

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Protein NH2-terminal asparagine deamidase. Isolation and characterization of a new enzyme

The Journal of biological chemistry, 1994-09, Vol.269 (38), p.23509-23517

1994

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The disulfide bond pairing of the pheromones Er‐1 and Er‐2 of the ciliated protozoan Euplotes raikovi

Protein science, 1992-06, Vol.1 (6), p.777-785

1992

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The great conspiracy trial of '69. (Chicago conspiracy trial)

The Nation (New York, N.Y.), 1979-09, Vol.229, p.257

1979

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Advancing Crop Transformation in the Era of Genome Editing

The Plant cell, 2016-07, Vol.28 (7), p.1510-1520

2016

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NGA-West2 database

Earthquake spectra, 2014-08, Vol.30 (3), p.989-1005

2014

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Measuring Antimicrobial Efficacy against Biofilms: a Meta-analysis

Antimicrobial agents and chemotherapy, 2019-05, Vol.63 (5)

2019

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Direct electric current treatment under physiologic saline conditions kills Staphylococcus epidermidis biofilms via electrolytic generation of hypochlorous acid

PloS one, 2013-02, Vol.8 (2), p.e55118

2013

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Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists

Molecular cell, 2020-11, Vol.80 (3), p.485-500.e7

2020

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Testosterone therapy, association with age, initiation and mode of therapy with cardiovascular events: a systematic review

Clinical endocrinology (Oxford), 2016-09, Vol.85 (3), p.436-443

2016

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Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3‑(5-Fluoro‑1H‑indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate

HGF/c-Met acts as an alternative angiogenic pathway in sunitinib-resistant tumors

Design of Potent and Selective Inhibitors to Overcome Clinical Anaplastic Lymphoma Kinase Mutations Resistant to Crizotinib

Characterization of Specific N -α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library

Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation

Incorporating anomalous scattering centres into macromolecules

Eukaryotic Methionyl Aminopeptidases: Two Classes of Cobalt-Dependent Enzymes

Analysis of protein modifications: recent advances in detection, characterization and mapping

A Mouse Amidase Specific for N-terminal Asparagine

A mouse amidase specific for N-terminal asparagine. The gene, the enzyme, and their function in the N-end rule pathway

The Sequence of Porcine Protein NH2-terminal Asparagine Amidohydrolase

The Sequence of Porcine Protein NH-terminal Asparagine Amidohydrolase

Protein NH2-terminal asparagine deamidase. Isolation and characterization of a new enzyme

The disulfide bond pairing of the pheromones Er‐1 and Er‐2 of the ciliated protozoan Euplotes raikovi

The great conspiracy trial of '69. (Chicago conspiracy trial)

Advancing Crop Transformation in the Era of Genome Editing

NGA-West2 database

Measuring Antimicrobial Efficacy against Biofilms: a Meta-analysis

Direct electric current treatment under physiologic saline conditions kills Staphylococcus epidermidis biofilms via electrolytic generation of hypochlorous acid

Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists

Testosterone therapy, association with age, initiation and mode of therapy with cardiovascular events: a systematic review

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