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Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A‐841720, a novel non‐competitive mGluR1 receptor antagonist

British journal of pharmacology, 2006-11, Vol.149 (6), p.761-774

2006

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Discovery of 4-Amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin- 3-yl)pyrido[2,3-d]pyrimidine, an Orally Active, Non-Nucleoside Adenosine Kinase Inhibitor

Journal of medicinal chemistry, 2001-06, Vol.44 (13), p.2133-2138

2001

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Symmetrical Bis(heteroarylmethoxyphenyl)alkylcarboxylic Acids as Inhibitors of Leukotriene Biosynthesis

Journal of medicinal chemistry, 2000-08, Vol.43 (17), p.3322-3334

2000

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Selective Inhibition of ICAM-1 and E-Selectin Expression in Human Endothelial Cells. 2. Aryl Modifications of 4-(Aryloxy)thieno[2,3-c]pyridines with Fine-Tuning at C-2 Carbamides

Journal of medicinal chemistry, 2001-10, Vol.44 (21), p.3469-3487

2001

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Heteroarylmethoxyphenylalkoxyiminoalkylcarboxylic Acids as Leukotriene Biosynthesis Inhibitors

Journal of medicinal chemistry, 2000-02, Vol.43 (4), p.690-705

2000

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Optimization of the potency and duration of action of N-hydroxyurea 5-lipoxygenase inhibitors

The Journal of pharmacology and experimental therapeutics, 1995-02, Vol.272 (2), p.724

1995

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(R)-(+)-N-[3-[5-[4-fluorophenylmethyl]-2-thienyl]-1-methyl-2-propynyl]-N-hydroxyurea (ABT-761), a second-generation 5-lipoxygenase inhibitor

Journal of medicinal chemistry, 1995-11, Vol.38 (24), p.4768-4775

1995

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Improving the in vivo duration of 5-lipoxygenase inhibitors: application of an in vitro glucuronosyltransferase assay

Drug metabolism and disposition, 1997-09, Vol.25 (9), p.1032

1997

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Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships

Journal of medicinal chemistry, 1990-03, Vol.33 (3), p.992-998

1990

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Design of inhibitors of leukotriene biosynthesis and their therapeutic potential

Pure and applied chemistry, 1998-02, Vol.70 (2), p.271-274

1998

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Preclinical and Clinical Activity of Zileuton and A-78773

Annals of the New York Academy of Sciences, 1993-11, Vol.696 (1), p.205-215

1993

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Structure-activity analysis of a class of orally active hydroxamic acid inhibitors of leukotriene biosynthesis

Journal of medicinal chemistry, 1988-10, Vol.31 (10), p.1960-1964

1988

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Structure–activity studies of 5-substituted pyridopyrimidines as adenosine kinase inhibitors

Bioorganic & medicinal chemistry letters, 2001-01, Vol.11 (1), p.83-86

2001

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Pyridopyrimidine analogues as novel adenosine kinase inhibitors

Bioorganic & medicinal chemistry letters, 2001-08, Vol.11 (16), p.2071-2074

2001

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Orally active hydroxamic acid inhibitors of leukotriene biosynthesis

Journal of medicinal chemistry, 1988-01, Vol.31 (1), p.3-5

1988

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Diagnosis and Treatment of Dystonia

Neurologic clinics, 2015-02, Vol.33 (1), p.77-100

2015

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Second generation leukotriene biosynthesis inhibitors

Pure and applied chemistry, 1994-01, Vol.66 (10), p.2197-2200

1994

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Changes in Firefighter Weight and Cardiovascular Disease Risk Factors over Five Years

Medicine and science in sports and exercise, 2020-11, Vol.52 (11), p.2476-2482

2020

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2-Siloxy-4-furanyl Anion: Remarkable Solvent Effect on Its Nucleophilicity

Synlett, 2000, Vol.2000 (9), p.1324-1326

2000

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Electrophysiological and in vivo characterization of A-317567, a novel blocker of acid sensing ion channels

Pain (Amsterdam), 2005-09, Vol.117 (1), p.88-96

2005

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N,O-Bis(phenoxycarbonyl)hydroxylamine: a new reagent for the direct synthesis of substituted N-hydroxyureas

Journal of organic chemistry, 1992-08, Vol.57 (18), p.5020-5023

1992

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Structure−Activity Relationships of N-Hydroxyurea 5-Lipoxygenase Inhibitors

Journal of medicinal chemistry, 1997-06, Vol.40 (13), p.1955-1968

1997

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C-Glycosidation of pyridyl thioglycosides

Journal of the American Chemical Society, 1985-07, Vol.107 (14), p.4289-4296

1985

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A-1048400 is a novel, orally active, state-dependent neuronal calcium channel blocker that produces dose-dependent antinociception without altering hemodynamic function in rats

Biochemical pharmacology, 2012-02, Vol.83 (3), p.406-418

2012

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Stereoselective Metabolism of the 5-Lipoxygenase Inhibitor A-78773

Annals of the New York Academy of Sciences, 1994-11, Vol.744 (1), p.262-273

1994

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Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A‐841720, a novel non‐competitive mGluR1 receptor antagonist

Discovery of 4-Amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin- 3-yl)pyrido[2,3-d]pyrimidine, an Orally Active, Non-Nucleoside Adenosine Kinase Inhibitor

Symmetrical Bis(heteroarylmethoxyphenyl)alkylcarboxylic Acids as Inhibitors of Leukotriene Biosynthesis

Selective Inhibition of ICAM-1 and E-Selectin Expression in Human Endothelial Cells. 2. Aryl Modifications of 4-(Aryloxy)thieno[2,3-c]pyridines with Fine-Tuning at C-2 Carbamides

Heteroarylmethoxyphenylalkoxyiminoalkylcarboxylic Acids as Leukotriene Biosynthesis Inhibitors

Optimization of the potency and duration of action of N-hydroxyurea 5-lipoxygenase inhibitors

(R)-(+)-N-[3-[5-[4-fluorophenylmethyl]-2-thienyl]-1-methyl-2-propynyl]-N-hydroxyurea (ABT-761), a second-generation 5-lipoxygenase inhibitor

Improving the in vivo duration of 5-lipoxygenase inhibitors: application of an in vitro glucuronosyltransferase assay

Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships

Design of inhibitors of leukotriene biosynthesis and their therapeutic potential

Preclinical and Clinical Activity of Zileuton and A-78773

Structure-activity analysis of a class of orally active hydroxamic acid inhibitors of leukotriene biosynthesis

Structure–activity studies of 5-substituted pyridopyrimidines as adenosine kinase inhibitors

Pyridopyrimidine analogues as novel adenosine kinase inhibitors

Orally active hydroxamic acid inhibitors of leukotriene biosynthesis

Diagnosis and Treatment of Dystonia

Second generation leukotriene biosynthesis inhibitors

Changes in Firefighter Weight and Cardiovascular Disease Risk Factors over Five Years

2-Siloxy-4-furanyl Anion: Remarkable Solvent Effect on Its Nucleophilicity

Electrophysiological and in vivo characterization of A-317567, a novel blocker of acid sensing ion channels

N,O-Bis(phenoxycarbonyl)hydroxylamine: a new reagent for the direct synthesis of substituted N-hydroxyureas

Structure−Activity Relationships of N-Hydroxyurea 5-Lipoxygenase Inhibitors

C-Glycosidation of pyridyl thioglycosides

A-1048400 is a novel, orally active, state-dependent neuronal calcium channel blocker that produces dose-dependent antinociception without altering hemodynamic function in rats

Stereoselective Metabolism of the 5-Lipoxygenase Inhibitor A-78773

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