UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Structural analysis of human KDM5B guides histone demethylase inhibitor development

Nature chemical biology, 2016-07, Vol.12 (7), p.539-545

2016

Volltextzugriff (PDF)

An Organometallic Inhibitor for the Human Repair Enzyme 7,8-Dihydro-8-oxoguanosine Triphosphatase

Angewandte Chemie (International ed.), 2014-01, Vol.53 (1), p.305-309

International ed. in English, 2014

Volltextzugriff (PDF)

Novel dengue virus NS2B/NS3 protease inhibitors

Antimicrobial agents and chemotherapy, 2015-02, Vol.59 (2), p.1100-1109

2015

Volltextzugriff (PDF)

Recent advances in targeting viral proteases for the discovery of novel antivirals

Current topics in medicinal chemistry, 2010-02, Vol.10 (3), p.323-345

2010

Volltextzugriff (PDF)

Structure and functionality in flavivirus NS-proteins: Perspectives for drug design

Antiviral research, 2010-08, Vol.87 (2), p.125-148

2010

Volltextzugriff (PDF)

The E. coli effector protein NleF is a caspase inhibitor

PloS one, 2013-03, Vol.8 (3), p.e58937

2013

Volltextzugriff (PDF)

Tracing Binding Modes in Hit-to-Lead Optimization: Chameleon-Like Poses of Aspartic Protease Inhibitors

Angewandte Chemie (International ed.), 2015-02, Vol.54 (9), p.2849-2853

International ed. in English, 2015

Volltextzugriff (PDF)

A combined spectroscopic and crystallographic approach to probing drug–human serum albumin interactions

Bioorganic & medicinal chemistry, 2010-11, Vol.18 (21), p.7486-7496

2010

Volltextzugriff (PDF)

Identification of Small Molecules that Modulate Mutant p53 Condensation

iScience, 2020-09, Vol.23 (9), p.101517-101517, Article 101517

2020

Volltextzugriff (PDF)

Factorizing Selectivity Determinants of Inhibitor Binding toward Aldose and Aldehyde Reductases: Structural and Thermodynamic Properties of the Aldose Reductase Mutant Leu300Pro−Fidarestat Complex

Journal of medicinal chemistry, 2005-09, Vol.48 (18), p.5659-5665

2005

Volltextzugriff (PDF)

Darolutamide is a potent androgen receptor antagonist with strong efficacy in prostate cancer models

International journal of cancer, 2019-09, Vol.145 (5), p.1382-1394

2019

Volltextzugriff (PDF)

An Old NSAID Revisited: Crystal Structure of Aldose Reductase in Complex with Sulindac at 1.0 Å Supports a Novel Mechanism for its Anticancer and Antiproliferative Effects

ChemMedChem, 2011-12, Vol.6 (12), p.2155-2157

Steuber, Holger

2011

Volltextzugriff (PDF)

Privileged Structures Meet Human T-Cell Leukemia Virus-1 (HTLV-1): C 2 -Symmetric 3,4-Disubstituted Pyrrolidines as Nonpeptidic HTLV-1 Protease Inhibitors

Journal of medicinal chemistry, 2015-06, Vol.58 (11), p.4845-4850

2015

Volltextzugriff (PDF)

Thermodynamic Inhibition Profile of a Cyclopentyl and a Cyclohexyl Derivative towards Thrombin: The Same but for Different Reasons

Angewandte Chemie (International ed.), 2007-01, Vol.46 (44), p.8511-8514

2007

Volltextzugriff (PDF)

Macrocyclic Statine-Based Inhibitors of BACE-1

Chembiochem : a European journal of chemical biology, 2007-11, Vol.8 (17), p.2078-2091

2007

Volltextzugriff (PDF)

Structural and Thermodynamic Study on Aldose Reductase: Nitro-substituted Inhibitors with Strong Enthalpic Binding Contribution

Journal of molecular biology, 2007-05, Vol.368 (3), p.618-638

2007

Volltextzugriff (PDF)

Structural Basis for HTLV‑1 Protease Inhibition by the HIV‑1 Protease Inhibitor Indinavir

Journal of medicinal chemistry, 2014-07, Vol.57 (14), p.6266-6272

2014

Volltextzugriff (PDF)

XanthomoninsI-III: A New Class of Lasso Peptides with a Seven-Residue Macrolactam Ring

Angewandte Chemie International Edition, 2014-02, Vol.53 (8), p.2230-2234

International ed. in English, 2014

Volltextzugriff (PDF)

Xanthomonins I-III: A New Class of Lasso Peptides with a Seven-Residue Macrolactam Ring

Angewandte Chemie (International ed.), 2014-02, Vol.53 (8), p.2230-2234

International ed. in English, 2014

Volltextzugriff (PDF)

Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839

Journal of medicinal chemistry, 2024-01, Vol.67 (2), p.1225-1242

2024

Volltextzugriff (PDF)

Structural Hot Spots Determine Functional Diversity of the Candida glabrata Epithelial Adhesin Family

The Journal of biological chemistry, 2015-08, Vol.290 (32), p.19597-19613

2015

Volltextzugriff (PDF)

BAY-7081: A Potent, Selective, and Orally Bioavailable Cyanopyridone-Based PDE9A Inhibitor

Journal of medicinal chemistry, 2022-12, Vol.65 (24), p.16420-16431

2022

Volltextzugriff (PDF)

Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling

Cell chemical biology, 2024-07, Vol.31 (7), p.1247-1263.e16

2024

Volltextzugriff (PDF)

Privileged Structures Meet Human T‑Cell Leukemia Virus‑1 (HTLV-1): C2‑Symmetric 3,4-Disubstituted Pyrrolidines as Nonpeptidic HTLV‑1 Protease Inhibitors

Journal of medicinal chemistry, 2015-06, Vol.58 (11), p.4845-4850

2015

Volltextzugriff (PDF)

Expect the Unexpected or Caveat for Drug Designers: Multiple Structure Determinations Using Aldose Reductase Crystals Treated under Varying Soaking and Co-crystallisation Conditions

Journal of molecular biology, 2006-10, Vol.363 (1), p.174-187

2006

Volltextzugriff (PDF)

1 – 25 von 75

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(73)
Mit Volltextzugriff
(70)

Publikationsform

Sprache

Englisch
(68)
Deutsch
(7)

Erscheinungsjahr

n.n

Thema

Science & Technology
(47)
Life Sciences & Biomedicine
(33)
Humans
(29)
Chemistry
(18)
Models, Molecular
(17)
Physical Sciences
(16)
Binding Sites
(15)
Biochemistry & Molecular Biology
(15)
Pharmacology & Pharmacy
(15)
Crystallography, X-Ray
(14)
Chemistry, Medicinal
(13)
Enzyme Inhibitors - Chemistry
(12)
Structure-Activity Relationship
(12)
Aldehyde Reductase - Antagonists & Inhibitors
(10)
Drug Design
(10)
Aldose Reductase
(9)
Enzyme Inhibitors - Pharmacology
(9)
Ligands
(9)
Chemistry, Multidisciplinary
(8)
Animals
(7)

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Structural analysis of human KDM5B guides histone demethylase inhibitor development

An Organometallic Inhibitor for the Human Repair Enzyme 7,8-Dihydro-8-oxoguanosine Triphosphatase

Novel dengue virus NS2B/NS3 protease inhibitors

Recent advances in targeting viral proteases for the discovery of novel antivirals

Structure and functionality in flavivirus NS-proteins: Perspectives for drug design

The E. coli effector protein NleF is a caspase inhibitor

Tracing Binding Modes in Hit-to-Lead Optimization: Chameleon-Like Poses of Aspartic Protease Inhibitors

A combined spectroscopic and crystallographic approach to probing drug–human serum albumin interactions

Identification of Small Molecules that Modulate Mutant p53 Condensation

Factorizing Selectivity Determinants of Inhibitor Binding toward Aldose and Aldehyde Reductases: Structural and Thermodynamic Properties of the Aldose Reductase Mutant Leu300Pro−Fidarestat Complex

Darolutamide is a potent androgen receptor antagonist with strong efficacy in prostate cancer models

An Old NSAID Revisited: Crystal Structure of Aldose Reductase in Complex with Sulindac at 1.0 Å Supports a Novel Mechanism for its Anticancer and Antiproliferative Effects

Privileged Structures Meet Human T-Cell Leukemia Virus-1 (HTLV-1): C 2 -Symmetric 3,4-Disubstituted Pyrrolidines as Nonpeptidic HTLV-1 Protease Inhibitors

Thermodynamic Inhibition Profile of a Cyclopentyl and a Cyclohexyl Derivative towards Thrombin: The Same but for Different Reasons

Macrocyclic Statine-Based Inhibitors of BACE-1

Structural and Thermodynamic Study on Aldose Reductase: Nitro-substituted Inhibitors with Strong Enthalpic Binding Contribution

Structural Basis for HTLV‑1 Protease Inhibition by the HIV‑1 Protease Inhibitor Indinavir

XanthomoninsI-III: A New Class of Lasso Peptides with a Seven-Residue Macrolactam Ring

Xanthomonins I-III: A New Class of Lasso Peptides with a Seven-Residue Macrolactam Ring

Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839

Structural Hot Spots Determine Functional Diversity of the Candida glabrata Epithelial Adhesin Family

BAY-7081: A Potent, Selective, and Orally Bioavailable Cyanopyridone-Based PDE9A Inhibitor

Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling

Privileged Structures Meet Human T‑Cell Leukemia Virus‑1 (HTLV-1): C2‑Symmetric 3,4-Disubstituted Pyrrolidines as Nonpeptidic HTLV‑1 Protease Inhibitors

Expect the Unexpected or Caveat for Drug Designers: Multiple Structure Determinations Using Aldose Reductase Crystals Treated under Varying Soaking and Co-crystallisation Conditions

Suchergebnisse filtern