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DOT1L inhibitors block abnormal self-renewal induced by cohesin loss

Scientific reports, 2021-03, Vol.11 (1), p.7288-7288, Article 7288

2021

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Loss of Fbxw7 triggers mammary tumorigenesis associated with E2F/c-Myc activation and Trp53 mutation

Neoplasia (New York, N.Y.), 2020-11, Vol.22 (11), p.644-658

2020

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Enhancer transcribed RNAs arise from hypomethylated, Tet-occupied genomic regions

Epigenetics, 2013-12, Vol.8 (12), p.1303-1320

2013

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Cohesin Loss Dominantly Influences the Accessibility Landscape of Npm1cA/+ AML

Blood, 2022-11, Vol.140 (Supplement 1), p.5884-5884

2022

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The cohesin-associated protein Wapal is required for proper Polycomb-mediated gene silencing

Epigenetics & chromatin, 2016-04, Vol.9 (14), p.14-14, Article 14

2016

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Abstract P152: Chromatin Accessibility Landscape Of The Proximal Tubule And Thick Ascending Limb In Humans And Rats

Hypertension (Dallas, Tex. 1979), 2023-09, Vol.80 (Suppl_1)

2023

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Histone Modifications and Their Contributions to Hypertension

Hypertension (Dallas, Tex. 1979), 2024-02, Vol.81 (2), p.229

2024

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Effects of hydroxyapatite particulate debris on the production of cytokines and proteases in human fibroblasts

Journal of orthopaedic research, 2001-07, Vol.19 (4), p.621-628

2001

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Genome editing demonstrates that the −5 kb Nanog enhancer regulates Nanog expression by modulating RNAPII initiation and/or recruitment

The Journal of biological chemistry, 2021-01, Vol.296, p.100189-100189, Article 100189

2021

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The cohesin subunit Rad21 is a negative regulator of hematopoietic self-renewal through epigenetic repression of Hoxa7 and Hoxa9

Leukemia, 2017-03, Vol.31 (3), p.712-719

2017

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Combinatorial Genetic Uncovers DOCK1/RAC2 As Specific Targets for the Treatment of NPM1;Cohesin Mutated AML

Blood, 2021-11, Vol.138 (Supplement 1), p.3288-3288

2021

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Combinatorial genetics reveals the Dock1-Rac2 axis as a potential target for the treatment of NPM1;Cohesin mutated AML

Leukemia, 2022-08, Vol.36 (8), p.2032-2041

2022

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Combinatorial Genetics Uncovers Novel Targets for the Treatment of Npm1/Cohesin Mutated AML

Blood, 2019-11, Vol.134 (Supplement_1), p.2515-2515

2019

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Nmp1 and Cohesin Mutations Cooperate to Generate Acute Myeloid Leukemia

Blood, 2017-12, Vol.130, p.1206-1206

2017

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Combinatorial Genetics Uncovers Novel Targets for the Treatment of Npm1/Cohesin Mutated AML

Blood, 2018-11, Vol.132 (Supplement 1), p.2598-2598

2018

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Prematurity in mice leads to reduction in nephron number, hypertension, and proteinuria

Translational research : the journal of laboratory and clinical medicine, 2012-02, Vol.159 (2), p.80-89

2012

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Stem Cell Factor Sall4 Regulates Normal and Malignant Hematopoiesis In an Isoform-Specific Manner

Blood, 2013-11, Vol.122 (21), p.3728-3728

2013

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Dot1l Reverses the Abnormal Self-Renewal Conferred on HSPCs through Cohesin Haploinsufficiency By Diminishing Expression of Hoxa7 and Hoxa9

Blood, 2017-12, Vol.130, p.246-246

2017

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Sall4 overexpression blocks murine hematopoiesis in a dose-dependent manner

Experimental hematology, 2015-01, Vol.43 (1), p.53-64.e8

2015

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The Cohesin Subunit Rad21 Is a Negative Regulator of Hematopoietic Self-Renewal through Epigenetic Repression of HoxA7 and HoxA9

Blood, 2016-12, Vol.128 (22), p.1708-1708

2016

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Genetic Variants in Arhgef11 Are Associated With Kidney Injury in the Dahl Salt-Sensitive Rat

Hypertension (Dallas, Tex. 1979), 2012-11, Vol.60 (5), p.1157-1168

2012

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Interaction of nonylphenol and hepatic CYP1A in rats

Biochemical pharmacology, 1996-09, Vol.52 (6), p.885-889

1996

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Heterogeneous stock rats: a new model to study the genetics of renal phenotypes

American Journal of Physiology - Renal Physiology, 2010-06, Vol.298 (6), p.F1484-F1491

2010

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GENETIC VARIANTS IN ARHGEF11 ARE ASSOCIATED WITH KIDNEY INJURY IN THE DAHL S RAT

Hypertension (Dallas, Tex. 1979), 2012-09, Vol.60 (5), p.1157-1168

2012

Volltextzugriff (PDF)

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DOT1L inhibitors block abnormal self-renewal induced by cohesin loss

Loss of Fbxw7 triggers mammary tumorigenesis associated with E2F/c-Myc activation and Trp53 mutation

Enhancer transcribed RNAs arise from hypomethylated, Tet-occupied genomic regions

Cohesin Loss Dominantly Influences the Accessibility Landscape of Npm1cA/+ AML

The cohesin-associated protein Wapal is required for proper Polycomb-mediated gene silencing

Abstract P152: Chromatin Accessibility Landscape Of The Proximal Tubule And Thick Ascending Limb In Humans And Rats

Histone Modifications and Their Contributions to Hypertension

Effects of hydroxyapatite particulate debris on the production of cytokines and proteases in human fibroblasts

Genome editing demonstrates that the −5 kb Nanog enhancer regulates Nanog expression by modulating RNAPII initiation and/or recruitment

The cohesin subunit Rad21 is a negative regulator of hematopoietic self-renewal through epigenetic repression of Hoxa7 and Hoxa9

Combinatorial Genetic Uncovers DOCK1/RAC2 As Specific Targets for the Treatment of NPM1;Cohesin Mutated AML

Combinatorial genetics reveals the Dock1-Rac2 axis as a potential target for the treatment of NPM1;Cohesin mutated AML

Decitabine and vorinostat with FLAG chemotherapy in pediatric relapsed/refractory AML: Report from the therapeutic advances in childhood leukemia and lymphoma (TACL) consortium

Combinatorial Genetics Uncovers Novel Targets for the Treatment of Npm1/Cohesin Mutated AML

Nmp1 and Cohesin Mutations Cooperate to Generate Acute Myeloid Leukemia

Combinatorial Genetics Uncovers Novel Targets for the Treatment of Npm1/Cohesin Mutated AML

Prematurity in mice leads to reduction in nephron number, hypertension, and proteinuria

Stem Cell Factor Sall4 Regulates Normal and Malignant Hematopoiesis In an Isoform-Specific Manner

Dot1l Reverses the Abnormal Self-Renewal Conferred on HSPCs through Cohesin Haploinsufficiency By Diminishing Expression of Hoxa7 and Hoxa9

Sall4 overexpression blocks murine hematopoiesis in a dose-dependent manner

The Cohesin Subunit Rad21 Is a Negative Regulator of Hematopoietic Self-Renewal through Epigenetic Repression of HoxA7 and HoxA9

Genetic Variants in Arhgef11 Are Associated With Kidney Injury in the Dahl Salt-Sensitive Rat

Interaction of nonylphenol and hepatic CYP1A in rats

Heterogeneous stock rats: a new model to study the genetics of renal phenotypes

GENETIC VARIANTS IN ARHGEF11 ARE ASSOCIATED WITH KIDNEY INJURY IN THE DAHL S RAT

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