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Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble

Molecular cell, 2015-05, Vol.58 (3), p.534-540

2015

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The Mechanism of E. coli RNA Polymerase Regulation by ppGpp Is Suggested by the Structure of their Complex

Molecular cell, 2013-05, Vol.50 (3), p.430-436

2013

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Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design

Annual review of biochemistry, 2018-06, Vol.87 (1), p.451-478

2018

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The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin

Nature structural & molecular biology, 2015-06, Vol.22 (6), p.466-469

2015

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Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly

Nature structural & molecular biology, 2015-04, Vol.22 (4), p.342-344

2015

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The initiation of mammalian protein synthesis and mRNA scanning mechanism

Nature (London), 2013-08, Vol.500 (7462), p.307-311

2013

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A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome

Nature structural & molecular biology, 2014-09, Vol.21 (9), p.787-793

2014

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Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation

Cell, 2015-01, Vol.160 (1-2), p.219-227

2015

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The Hexameric Helicase DnaB Adopts a Nonplanar Conformation during Translocation

Cell, 2012-10, Vol.151 (2), p.267-277

2012

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How Hibernation Factors RMF, HPF, and YfiA Turn Off Protein Synthesis

Science (American Association for the Advancement of Science), 2012-05, Vol.336 (6083), p.915-918

2012

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Revisiting the structures of several antibiotics bound to the bacterial ribosome

Proceedings of the National Academy of Sciences - PNAS, 2010-10, Vol.107 (40), p.17158-17163

2010

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Structural basis for the fast self-cleavage reaction catalyzed by the twister ribozyme

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (36), p.13028-13033

2014

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The structural changes of T7 RNA polymerase from transcription initiation to elongation

Current opinion in structural biology, 2009-12, Vol.19 (6), p.683-690

Steitz, Thomas A

2009

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Structural basis for transcription reactivation by RapA

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (7), p.2006-2010

2015

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From the Structure and Function of the Ribosome to New Antibiotics (Nobel Lecture)

Angewandte Chemie (International ed.), 2010-06, Vol.49 (26), p.4381-4398

Steitz, Thomas A

2010

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Poly(A) Tail Recognition by a Viral RNA Element Through Assembly of a Triple Helix

Science (American Association for the Advancement of Science), 2010-11, Vol.330 (6008), p.1244-1247

2010

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Polyspecific pyrrolysyl-tRNA synthetases from directed evolution

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (47), p.16724-16729

2014

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Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2- d ]pyrimidine non-nucleoside inhibitors

eLife, 2018-07, Vol.7 (2018)

2018

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Structural Basis for the Rescue of Stalled Ribosomes: Structure of YaeJ Bound to the Ribosome

Science (American Association for the Advancement of Science), 2012-03, Vol.335 (6074), p.1370-1372

2012

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Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome

Science (American Association for the Advancement of Science), 2014-08, Vol.345 (6197), p.684-687

2014

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Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance

Cell, 2005-04, Vol.121 (2), p.257-270

2005

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Elongation factor 4 remodels the A-site tRNA on the ribosome

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (18), p.4994-4999

2016

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Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit

Journal of medicinal chemistry, 2008-06, Vol.51 (12), p.3353-3356

2008

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Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A

Molecular cell, 2015-06, Vol.58 (5), p.832-844

2015

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A structural understanding of the dynamic ribosome machine

Nature reviews. Molecular cell biology, 2008-03, Vol.9 (3), p.242-253

Steitz, Thomas A

2008

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Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble

The Mechanism of E. coli RNA Polymerase Regulation by ppGpp Is Suggested by the Structure of their Complex

Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design

The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin

Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly

The initiation of mammalian protein synthesis and mRNA scanning mechanism

A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome

Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation

The Hexameric Helicase DnaB Adopts a Nonplanar Conformation during Translocation

How Hibernation Factors RMF, HPF, and YfiA Turn Off Protein Synthesis

Revisiting the structures of several antibiotics bound to the bacterial ribosome

Structural basis for the fast self-cleavage reaction catalyzed by the twister ribozyme

The structural changes of T7 RNA polymerase from transcription initiation to elongation

Structural basis for transcription reactivation by RapA

From the Structure and Function of the Ribosome to New Antibiotics (Nobel Lecture)

Poly(A) Tail Recognition by a Viral RNA Element Through Assembly of a Triple Helix

Polyspecific pyrrolysyl-tRNA synthetases from directed evolution

Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2- d ]pyrimidine non-nucleoside inhibitors

Structural Basis for the Rescue of Stalled Ribosomes: Structure of YaeJ Bound to the Ribosome

Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome

Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance

Elongation factor 4 remodels the A-site tRNA on the ribosome

Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit

Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A

A structural understanding of the dynamic ribosome machine

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