UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Carbazole-containing amides and ureas: Discovery of cryptochrome modulators as antihyperglycemic agents

Bioorganic & medicinal chemistry letters, 2018-02, Vol.28 (3), p.293-297

2018

Volltextzugriff (PDF)

Carbazole-containing sulfonamides and sulfamides: Discovery of cryptochrome modulators as antidiabetic agents

Bioorganic & medicinal chemistry letters, 2016-02, Vol.26 (3), p.757-760

2016

Volltextzugriff (PDF)

A Novel Multivalent Ligand That Bridges the Allosteric and Orthosteric Binding Sites of the M2 Muscarinic Receptor

Molecular pharmacology, 2007-08, Vol.72 (2), p.291-302

2007

Volltextzugriff (PDF)

Vasopressin 1A (V1A) Receptor Antagonists Reduce Anxiety in Marmosets

Biological psychiatry (1969), 2020-05, Vol.87 (9), p.S239

2020

Volltextzugriff (PDF)

A Novel Multivalent Ligand That Bridges the Allosteric and Orthosteric Binding Sites of the M 2 Muscarinic Receptor

Molecular pharmacology, 2007-08, Vol.72 (2), p.291-302

2007

Volltextzugriff (PDF)

Discovery of (R)‑1-(3-((2-Chloro-4-(((2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)methyl)-5-methoxyphenyl)amino)-3-oxopropyl)piperidin-4-yl [1,1′-Biphenyl]-2-ylcarbamate (TD-5959, GSK961081, Batefenterol): First-in-Class Dual Pharmacology Multivalent Muscarinic Antagonist and β2 Agonist (MABA) for the Treatment of Chronic Obstructive Pulmonary Disease (COPD)

Journal of medicinal chemistry, 2015-03, Vol.58 (6), p.2609-2622

2015

Volltextzugriff (PDF)

Discovery of ( R )-1-(3-((2-Chloro-4-(((2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)methyl)-5-methoxyphenyl)amino)-3-oxopropyl)piperidin-4-yl [1,1′-Biphenyl]-2-ylcarbamate (TD-5959, GSK961081, Batefenterol): First-in-Class Dual Pharmacology Multivalent Muscarinic Antagonist and β 2 Agonist (MABA) for the Treatment of Chronic Obstructive Pulmonary Disease (COPD)

Journal of medicinal chemistry, 2015-03, Vol.58 (6), p.2609-2622

2015

Volltextzugriff (PDF)

Pharmacologic characterization of GSK-961081 (TD-5959), a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties

The Journal of pharmacology and experimental therapeutics, 2014-10, Vol.351 (1), p.190

2014

Volltextzugriff (PDF)

Pharmacologic Characterization of GSK-961081 (TD-5959), a First-in-Class Inhaled Bifunctional Bronchodilator Possessing Muscarinic Receptor Antagonist and β 2 -Adrenoceptor Agonist Properties

The Journal of pharmacology and experimental therapeutics, 2014-10, Vol.351 (1), p.190-199

2014

Volltextzugriff (PDF)

Pharmacological properties of revefenacin (TD‐4208), a novel, nebulized long‐acting, and lung selective muscarinic antagonist, at human recombinant muscarinic receptors and in rat, guinea pig, and human isolated airway tissues

Pharmacology research & perspectives, 2018-06, Vol.6 (3), p.e00400-n/a

2018

Volltextzugriff (PDF)

A multivalent approach towards linked dual-pharmacology prostaglandin F receptor agonist/carbonic anhydrase-II inhibitors for the treatment of glaucoma

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (4), p.939-943

2013

Volltextzugriff (PDF)

THRX-198321 Is a Bifunctional Muscarinic Receptor Antagonist and β 2 -Adrenoceptor Agonist (MABA) That Binds in a Bimodal and Multivalent Manner

Molecular pharmacology, 2011-03, Vol.79 (3), p.389-399

2011

Volltextzugriff (PDF)

Preclinical efficacy of THRX-200495, a dual pharmacology muscarinic receptor antagonist and β2 -adrenoceptor agonist (MABA)

Pulmonary pharmacology & therapeutics, 2012-10, Vol.25 (5), p.357-363

2012

Volltextzugriff (PDF)

Discovery of muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonist (MABA) dual pharmacology molecules

Bioorganic & medicinal chemistry letters, 2011-03, Vol.21 (5), p.1354-1358

2011

Volltextzugriff (PDF)

Muscarinic receptor subtypes and signalling involved in the attenuation of isoprenaline-induced rat urinary bladder relaxation

Naunyn-Schmiedeberg's archives of pharmacology, 2011-12, Vol.384 (6), p.555-563

2011

Volltextzugriff (PDF)

Preclinical efficacy of THRX-200495, a dual pharmacology muscarinic receptor antagonist and β(2)-adrenoceptor agonist (MABA)

Pulmonary pharmacology & therapeutics, 2012-10, Vol.25 (5), p.357-363

2012

Volltextzugriff (PDF)

THRX‐198321: A bifunctional muscarinic receptor antagonist and beta2‐adrenoceptor agonist which binds in a bimodal multivalent fashion to orthosteric and allosteric sites at both receptors

The FASEB journal, 2009-04, Vol.23 (S1)

2009

Volltextzugriff (PDF)

Allosteric modulation of muscarinic receptors by the multivalent ligand THRX‐160209

The FASEB journal, 2006-03, Vol.20 (5), p.A1118-A1119

2006

Volltextzugriff (PDF)

A Novel Multivalent Ligand That Bridges the Allosteric and Orthosteric Binding Sites of the M sub(2) Muscarinic Receptor

Molecular pharmacology, 2007-08, Vol.72 (2), p.291-302

2007

Volltextzugriff (PDF)

Pharmacological properties of TD-6301, a novel bladder selective muscarinic receptor antagonist

European journal of pharmacology, 2009-03, Vol.605 (1), p.145-152

2009

Volltextzugriff (PDF)

A multivalent ligand that bridges the orthosteric and allosteric sites of the muscarinic M 2 receptor

The FASEB journal, 2006-03, Vol.20 (5)

2006

Volltextzugriff (PDF)

A multivalent ligand that bridges the orthosteric and allosteric sites of the muscarinic M2 receptor

The FASEB journal, 2006-03, Vol.20 (5), p.A1118-A1118

2006

Volltextzugriff (PDF)

Multivalent dual pharmacology muscarinic antagonist and β₂ agonist (MABA) molecules for the treatment of COPD

Progress in medicinal chemistry, 2012, Vol.51, p.71

2012

Volltextzugriff (PDF)

THRX-198321 is a bifunctional muscarinic receptor antagonist and beta2-adrenoceptor agonist (MABA) that binds in a bimodal and multivalent manner

Molecular pharmacology, 2011-03, Vol.79 (3), p.389-399

2011

Volltextzugriff (PDF)

In Vivo Pharmacodynamic Assays for M 2 and M 3 Muscarinic Receptors

Current Protocols in Pharmacology, 2010-03, Vol.48 (1)

2010

Volltextzugriff (PDF)

1 – 25 von 28

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(24)
Mit Volltextzugriff
(25)

Publikationsform

Artikel
(27)
Buchkapitel
(1)

Sprache

Englisch
(28)

Erscheinungsjahr

n.n

Thema

Animals
(12)
Muscarinic Antagonists - Pharmacology
(10)
Humans
(9)
Life Sciences & Biomedicine
(9)
Pharmacology & Pharmacy
(9)
Science & Technology
(9)
Cho Cells
(5)
Cricetulus
(5)
Guinea Pigs
(5)
Muscarinic
(5)
Muscarinic Agonists - Pharmacology
(5)
Rats
(5)
Adrenergic Beta-2 Receptor Agonists - Pharmacology
(4)
Carbamates - Pharmacology
(4)
Chemistry
(4)
Chemistry, Medicinal
(4)
Chemistry, Organic
(4)
Cricetinae
(4)
Male
(4)
Physical Sciences
(4)

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Carbazole-containing amides and ureas: Discovery of cryptochrome modulators as antihyperglycemic agents

Carbazole-containing sulfonamides and sulfamides: Discovery of cryptochrome modulators as antidiabetic agents

A Novel Multivalent Ligand That Bridges the Allosteric and Orthosteric Binding Sites of the M2 Muscarinic Receptor

Vasopressin 1A (V1A) Receptor Antagonists Reduce Anxiety in Marmosets

A Novel Multivalent Ligand That Bridges the Allosteric and Orthosteric Binding Sites of the M 2 Muscarinic Receptor

Pharmacologic characterization of GSK-961081 (TD-5959), a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties

Pharmacologic Characterization of GSK-961081 (TD-5959), a First-in-Class Inhaled Bifunctional Bronchodilator Possessing Muscarinic Receptor Antagonist and β 2 -Adrenoceptor Agonist Properties

Pharmacological properties of revefenacin (TD‐4208), a novel, nebulized long‐acting, and lung selective muscarinic antagonist, at human recombinant muscarinic receptors and in rat, guinea pig, and human isolated airway tissues

A multivalent approach towards linked dual-pharmacology prostaglandin F receptor agonist/carbonic anhydrase-II inhibitors for the treatment of glaucoma

THRX-198321 Is a Bifunctional Muscarinic Receptor Antagonist and β 2 -Adrenoceptor Agonist (MABA) That Binds in a Bimodal and Multivalent Manner

Preclinical efficacy of THRX-200495, a dual pharmacology muscarinic receptor antagonist and β2 -adrenoceptor agonist (MABA)

Discovery of muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonist (MABA) dual pharmacology molecules

Muscarinic receptor subtypes and signalling involved in the attenuation of isoprenaline-induced rat urinary bladder relaxation

Preclinical efficacy of THRX-200495, a dual pharmacology muscarinic receptor antagonist and β(2)-adrenoceptor agonist (MABA)

THRX‐198321: A bifunctional muscarinic receptor antagonist and beta2‐adrenoceptor agonist which binds in a bimodal multivalent fashion to orthosteric and allosteric sites at both receptors

Allosteric modulation of muscarinic receptors by the multivalent ligand THRX‐160209

A Novel Multivalent Ligand That Bridges the Allosteric and Orthosteric Binding Sites of the M sub(2) Muscarinic Receptor

Pharmacological properties of TD-6301, a novel bladder selective muscarinic receptor antagonist

A multivalent ligand that bridges the orthosteric and allosteric sites of the muscarinic M 2 receptor

A multivalent ligand that bridges the orthosteric and allosteric sites of the muscarinic M2 receptor

Multivalent dual pharmacology muscarinic antagonist and β₂ agonist (MABA) molecules for the treatment of COPD

THRX-198321 is a bifunctional muscarinic receptor antagonist and beta2-adrenoceptor agonist (MABA) that binds in a bimodal and multivalent manner

In Vivo Pharmacodynamic Assays for M 2 and M 3 Muscarinic Receptors

Suchergebnisse filtern