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A Transporter Interactome Is Essential for the Acquisition of Antimicrobial Resistance to Antibiotics

PloS one, 2016-04, Vol.11 (4), p.e0152917

2016

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New Substrates on the Block: Clinically Relevant Resistances for EmrE and Homologues

Journal of Bacteriology, 2012-12, Vol.194 (24), p.6766-6770

2012

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In vitro Synthesis of Fully Functional EmrE, a Multidrug Transporter, and Study of Its Oligomeric State

Proceedings of the National Academy of Sciences - PNAS, 2004-02, Vol.101 (6), p.1519-1524

2004

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Parallel topology of genetically fused EmrE homodimers

The EMBO journal, 2008-01, Vol.27 (1), p.17-26

2008

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Identification of Tyrosine Residues Critical for the Function of an Ion-coupled Multidrug Transporter

The Journal of biological chemistry, 2006-07, Vol.281 (27), p.18715-18722

2006

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Crosslinking of Membrane-Embedded Cysteines Reveals Contact Points in the EmrE Oligomer

Proceedings of the National Academy of Sciences - PNAS, 2002-09, Vol.99 (19), p.12043-12048

2002

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Exploring the Binding Domain of EmrE, the Smallest Multidrug Transporter

The Journal of biological chemistry, 2005-09, Vol.280 (38), p.32849-32855

2005

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An Amino Acid Cluster around the Essential Glu-14 Is Part of the Substrate- and Proton-binding Domain of EmrE, a Multidrug Transporter from Escherichia coli

The Journal of biological chemistry, 2003-05, Vol.278 (18), p.16082-16087

2003

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Characterization of Bacterial Drug Antiporters Homologous to Mammalian Neurotransmitter Transporters

Journal of Bacteriology, 2005-11, Vol.187 (21), p.7518-7525

2005

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Scanning Cysteine Accessibility of EmrE, an H+-coupled Multidrug Transporter from Escherichia coli, Reveals a Hydrophobic Pathway for Solutes

The Journal of biological chemistry, 1999-07, Vol.274 (27), p.19480-19486

1999

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A Single Carboxyl Mutant of the Multidrug Transporter EmrE Is Fully Functional

The Journal of biological chemistry, 2001-04, Vol.276 (16), p.12744-12748

2001

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Modification of the pH Profile and Tetrabenazine Sensitivity of Rat VMAT1 by Replacement of Aspartate 404 with Glutamate

The Journal of biological chemistry, 1996-05, Vol.271 (22), p.13048-13054

1996

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Topologically Random Insertion of EmrE Supports a Pathway for Evolution of Inverted Repeats in Ion-coupled Transporters

The Journal of biological chemistry, 2010-05, Vol.285 (20), p.15234-15244

2010

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Substrate-Induced Tryptophan Fluorescence Changes in EmrE, the Smallest Ion-Coupled Multidrug Transporter

Biochemistry (Easton), 2005-05, Vol.44 (19), p.7369-7377

2005

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Glycosylation of a Vesicular Monoamine Transporter: A Mutation in a Conserved Proline Residue Affects the Activity, Glycosylation, and Localization of the Transporter

Journal of neurochemistry, 1998-12, Vol.71 (6), p.2518-2527

1998

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Cloning and functional expression of a tetrabenazine sensitive vesicular monoamine transporter from bovine chromaffin granules

FEBS letters, 1994-01, Vol.338 (1), p.16-22

1994

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Energetics of reserpine binding and occlusion by the chromaffin granule biogenic amine transporter

Biochemistry (Easton), 1990-01, Vol.29 (3), p.603-608

1990

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Histidine-419 plays a role in energy coupling in the vesicular monoamine transporter from rat

FEBS letters, 1994-12, Vol.356 (1), p.145-150

1994

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From Bacterial Antibiotic Resistance to Neurotransmitter Uptake

Annals of the New York Academy of Sciences, 1994-09, Vol.733 (1), p.174-184

1994

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Amphetamine derivatives interact with both plasma membrane and secretory vesicle biogenic amine transporters

Molecular pharmacology, 1993-12, Vol.44 (6), p.1227-1231

1993

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Topology determination of untagged membrane proteins

Methods in molecular biology (Clifton, N.J.), 2013, Vol.1033, p.121

2013

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Killing of intraerythrocytic Plasmodium falciparum by lysosomotropic amino acid esters

Parasitology research (1987), 2003-04, Vol.89 (6), p.451-458

2003

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Function of the delipidated β‐adrenergic receptor appears to require a fatty acid or a neutral lipid in addition to phospholipids

European journal of biochemistry, 1987-07, Vol.166 (1), p.221-228

1987

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Homology of a Vesicular Amine Transporter to a Gene Conferring Resistance to 1-Methyl-4-Phenylpyridinium

Proceedings of the National Academy of Sciences - PNAS, 1992-10, Vol.89 (20), p.9730-9733

1992

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Free fatty acids decouple oxidative phosphorylation by dissipating intramembranal protons without inhibiting ATP synthesis driven by the proton electrochemical gradient

FEBS letters, 1986-07, Vol.202 (2), p.314-318

1986

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A Transporter Interactome Is Essential for the Acquisition of Antimicrobial Resistance to Antibiotics

New Substrates on the Block: Clinically Relevant Resistances for EmrE and Homologues

In vitro Synthesis of Fully Functional EmrE, a Multidrug Transporter, and Study of Its Oligomeric State

Parallel topology of genetically fused EmrE homodimers

Identification of Tyrosine Residues Critical for the Function of an Ion-coupled Multidrug Transporter

Crosslinking of Membrane-Embedded Cysteines Reveals Contact Points in the EmrE Oligomer

Exploring the Binding Domain of EmrE, the Smallest Multidrug Transporter

An Amino Acid Cluster around the Essential Glu-14 Is Part of the Substrate- and Proton-binding Domain of EmrE, a Multidrug Transporter from Escherichia coli

Characterization of Bacterial Drug Antiporters Homologous to Mammalian Neurotransmitter Transporters

Scanning Cysteine Accessibility of EmrE, an H+-coupled Multidrug Transporter from Escherichia coli, Reveals a Hydrophobic Pathway for Solutes

A Single Carboxyl Mutant of the Multidrug Transporter EmrE Is Fully Functional

Modification of the pH Profile and Tetrabenazine Sensitivity of Rat VMAT1 by Replacement of Aspartate 404 with Glutamate

Topologically Random Insertion of EmrE Supports a Pathway for Evolution of Inverted Repeats in Ion-coupled Transporters

Substrate-Induced Tryptophan Fluorescence Changes in EmrE, the Smallest Ion-Coupled Multidrug Transporter

Glycosylation of a Vesicular Monoamine Transporter: A Mutation in a Conserved Proline Residue Affects the Activity, Glycosylation, and Localization of the Transporter

Cloning and functional expression of a tetrabenazine sensitive vesicular monoamine transporter from bovine chromaffin granules

Energetics of reserpine binding and occlusion by the chromaffin granule biogenic amine transporter

Histidine-419 plays a role in energy coupling in the vesicular monoamine transporter from rat

From Bacterial Antibiotic Resistance to Neurotransmitter Uptake

Amphetamine derivatives interact with both plasma membrane and secretory vesicle biogenic amine transporters

Topology determination of untagged membrane proteins

Killing of intraerythrocytic Plasmodium falciparum by lysosomotropic amino acid esters

Function of the delipidated β‐adrenergic receptor appears to require a fatty acid or a neutral lipid in addition to phospholipids

Homology of a Vesicular Amine Transporter to a Gene Conferring Resistance to 1-Methyl-4-Phenylpyridinium

Free fatty acids decouple oxidative phosphorylation by dissipating intramembranal protons without inhibiting ATP synthesis driven by the proton electrochemical gradient

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