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AMP-activated protein kinase: the current landscape for drug development

Nature reviews. Drug discovery, 2019-07, Vol.18 (7), p.527-551

2019

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AMPK as a Therapeutic Target for Treating Metabolic Diseases

Trends in endocrinology and metabolism, 2017-08, Vol.28 (8), p.545-560

2017

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AMPK in Health and Disease

Physiological reviews, 2009-07, Vol.89 (3), p.1025-1078

2009

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GDF15: emerging biology and therapeutic applications for obesity and cardiometabolic disease

Nature reviews. Endocrinology, 2021-10, Vol.17 (10), p.592-607

2021

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Emerging Roles for Serotonin in Regulating Metabolism: New Implications for an Ancient Molecule

Endocrine reviews, 2019-08, Vol.40 (4), p.1092-1107

2019

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High-intensity exercise training increases the diversity and metabolic capacity of the mouse distal gut microbiota during diet-induced obesity

American journal of physiology: endocrinology and metabolism, 2016-06, Vol.310 (11), p.E982-E993

2016

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Treatment of nonalcoholic fatty liver disease: role of AMPK

American journal of physiology: endocrinology and metabolism, 2016-10, Vol.311 (4), p.E730-E740

2016

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Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function

Cell metabolism, 2016-07, Vol.24 (1), p.118-129

2016

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Race/ethnicity reporting and representation in US clinical trials: A cohort study

Lancet Regional Health - Americas (Online), 2022-07, Vol.11, p.100252, Article 100252

2022

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Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis

Nature communications, 2016-11, Vol.7 (1), p.13457-13457, Article 13457

2016

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AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity

Molecular and cellular endocrinology, 2013-02, Vol.366 (2), p.135-151

2013

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The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels

Diabetes (New York, N.Y.), 2016-09, Vol.65 (9), p.2784-2794

2016

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AMPK Activation of Muscle Autophagy Prevents Fasting-Induced Hypoglycemia and Myopathy during Aging

Cell metabolism, 2015-06, Vol.21 (6), p.883-890

2015

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Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

Nature medicine, 2013-12, Vol.19 (12), p.1649-1654

2013

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Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis

Nature medicine, 2015-02, Vol.21 (2), p.166-172

2015

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Growth Differentiation Factor 15 as a Novel Biomarker for Metformin

Diabetes care, 2017-02, Vol.40 (2), p.280-283

2017

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Robert Schumann in the psychiatric hospital in Endenich near Bonn

Nervenarzt, 2017-11, Vol.88 (11), p.1298-1313

Steinberg, R

2017

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The role of AMPK in controlling metabolism and mitochondrial biogenesis during exercise

Experimental physiology, 2014-12, Vol.99 (12), p.1581-1585

2014

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MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis

The Journal of clinical investigation, 2015-12, Vol.125 (12), p.4334-4348

2015

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The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

Science (American Association for the Advancement of Science), 2012-05, Vol.336 (6083), p.918-922

2012

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Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4

Cell metabolism, 2017-05, Vol.25 (5), p.1063-1074.e3

2017

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The gut microbiome regulates host glucose homeostasis via peripheral serotonin

Proceedings of the National Academy of Sciences - PNAS, 2019-10, Vol.116 (40), p.19802-19804

2019

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Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance

Nature communications, 2022-02, Vol.13 (1), p.770-770, Article 770

2022

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Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss

Nature metabolism, 2019-12, Vol.1 (12), p.1202-1208

2019

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AMP-activated protein kinase: the current landscape for drug development

AMPK as a Therapeutic Target for Treating Metabolic Diseases

AMPK in Health and Disease

GDF15: emerging biology and therapeutic applications for obesity and cardiometabolic disease

Emerging Roles for Serotonin in Regulating Metabolism: New Implications for an Ancient Molecule

High-intensity exercise training increases the diversity and metabolic capacity of the mouse distal gut microbiota during diet-induced obesity

Treatment of nonalcoholic fatty liver disease: role of AMPK

Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function

Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma

Race/ethnicity reporting and representation in US clinical trials: A cohort study

Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis

AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity

The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels

AMPK Activation of Muscle Autophagy Prevents Fasting-Induced Hypoglycemia and Myopathy during Aging

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis

Growth Differentiation Factor 15 as a Novel Biomarker for Metformin

Robert Schumann in the psychiatric hospital in Endenich near Bonn

The role of AMPK in controlling metabolism and mitochondrial biogenesis during exercise

MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis

The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4

The gut microbiome regulates host glucose homeostasis via peripheral serotonin

Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance

Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss

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