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AMP-activated protein kinase: the current landscape for drug development

Nature reviews. Drug discovery, 2019-07, Vol.18 (7), p.527-551

2019

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AMPK as a Therapeutic Target for Treating Metabolic Diseases

Trends in endocrinology and metabolism, 2017-08, Vol.28 (8), p.545-560

2017

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AMPK in Health and Disease

Physiological reviews, 2009-07, Vol.89 (3), p.1025-1078

2009

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GDF15: emerging biology and therapeutic applications for obesity and cardiometabolic disease

Nature reviews. Endocrinology, 2021-10, Vol.17 (10), p.592-607

2021

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Emerging Roles for Serotonin in Regulating Metabolism: New Implications for an Ancient Molecule

Endocrine reviews, 2019-08, Vol.40 (4), p.1092-1107

2019

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High-intensity exercise training increases the diversity and metabolic capacity of the mouse distal gut microbiota during diet-induced obesity

American journal of physiology: endocrinology and metabolism, 2016-06, Vol.310 (11), p.E982-E993

2016

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Treatment of nonalcoholic fatty liver disease: role of AMPK

American journal of physiology: endocrinology and metabolism, 2016-10, Vol.311 (4), p.E730-E740

2016

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Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function

Cell metabolism, 2016-07, Vol.24 (1), p.118-129

2016

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Race/ethnicity reporting and representation in US clinical trials: A cohort study

Lancet Regional Health - Americas (Online), 2022-07, Vol.11, p.100252, Article 100252

2022

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Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis

Nature communications, 2016-11, Vol.7 (1), p.13457-13457, Article 13457

2016

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AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity

Molecular and cellular endocrinology, 2013-02, Vol.366 (2), p.135-151

2013

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The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels

Diabetes (New York, N.Y.), 2016-09, Vol.65 (9), p.2784-2794

2016

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AMPK Activation of Muscle Autophagy Prevents Fasting-Induced Hypoglycemia and Myopathy during Aging

Cell metabolism, 2015-06, Vol.21 (6), p.883-890

2015

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Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

Nature medicine, 2013-12, Vol.19 (12), p.1649-1654

2013

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Growth Differentiation Factor 15 as a Novel Biomarker for Metformin

Diabetes care, 2017-02, Vol.40 (2), p.280-283

2017

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The role of AMPK in controlling metabolism and mitochondrial biogenesis during exercise

Experimental physiology, 2014-12, Vol.99 (12), p.1581-1585

2014

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Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis

Nature medicine, 2015-02, Vol.21 (2), p.166-172

2015

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Robert Schumann in the psychiatric hospital in Endenich near Bonn

Nervenarzt, 2017-11, Vol.88 (11), p.1298-1313

Steinberg, R

2017

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MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis

The Journal of clinical investigation, 2015-12, Vol.125 (12), p.4334-4348

2015

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The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

Science (American Association for the Advancement of Science), 2012-05, Vol.336 (6083), p.918-922

2012

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Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4

Cell metabolism, 2017-05, Vol.25 (5), p.1063-1074.e3

2017

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Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss

Nature metabolism, 2019-12, Vol.1 (12), p.1202-1208

2019

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The gut microbiome regulates host glucose homeostasis via peripheral serotonin

Proceedings of the National Academy of Sciences - PNAS, 2019-10, Vol.116 (40), p.19802-19804

2019

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Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance

Nature communications, 2022-02, Vol.13 (1), p.770-770, Article 770

2022

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AMP-activated protein kinase: the current landscape for drug development

AMPK as a Therapeutic Target for Treating Metabolic Diseases

AMPK in Health and Disease

GDF15: emerging biology and therapeutic applications for obesity and cardiometabolic disease

Emerging Roles for Serotonin in Regulating Metabolism: New Implications for an Ancient Molecule

High-intensity exercise training increases the diversity and metabolic capacity of the mouse distal gut microbiota during diet-induced obesity

Treatment of nonalcoholic fatty liver disease: role of AMPK

Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function

Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma

Race/ethnicity reporting and representation in US clinical trials: A cohort study

Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis

AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity

The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels

AMPK Activation of Muscle Autophagy Prevents Fasting-Induced Hypoglycemia and Myopathy during Aging

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

Growth Differentiation Factor 15 as a Novel Biomarker for Metformin

The role of AMPK in controlling metabolism and mitochondrial biogenesis during exercise

Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis

Robert Schumann in the psychiatric hospital in Endenich near Bonn

MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis

The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4

Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss

The gut microbiome regulates host glucose homeostasis via peripheral serotonin

Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance

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