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Reduction in Lipoprotein(a) With PCSK9 Monoclonal Antibody Evolocumab (AMG 145)

Journal of the American College of Cardiology, 2014-04, Vol.63 (13), p.1278-1288

2014

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Safety and Efficacy of a Monoclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 Serine Protease, SAR236553/REGN727, in Patients With Primary Hypercholesterolemia Receiving Ongoing Stable Atorvastatin Therapy

Journal of the American College of Cardiology, 2012-06, Vol.59 (25), p.2344-2353

2012

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Effect of Alirocumab, a Monoclonal Proprotein Convertase Subtilisin/Kexin 9 Antibody, on Lipoprotein(a) Concentrations (a Pooled Analysis of 150 mg Every Two Weeks Dosing from Phase 2 Trials)

The American journal of cardiology, 2014-09, Vol.114 (5), p.711-715

2014

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Effect of Mipomersen, an Apolipoprotein B Synthesis Inhibitor, on Low-Density Lipoprotein Cholesterol in Patients With Familial Hypercholesterolemia

The American journal of cardiology, 2010-05, Vol.105 (10), p.1413-1419

2010

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Efficacy and tolerability of adding prescription Omega-3 fatty acids 4 g/d to Simvastatin 40 mg/d in hypertriglyceridemic patients: An 8-week, randomized, double-blind, placebo-controlled study

Clinical therapeutics, 2007-07, Vol.29 (7), p.1354-1367

2007

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Efficacy and Safety of Rosuvastatin Therapy for Children With Familial Hypercholesterolemia

Journal of the American College of Cardiology, 2010-03, Vol.55 (11), p.1121-1126

2010

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Non-statin Treatments for Managing LDL Cholesterol and Their Outcomes

Clinical therapeutics, 2015-12, Vol.37 (12), p.2751-2769

2015

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Safety and Tolerability of Dalcetrapib

The American journal of cardiology, 2009-07, Vol.104 (1), p.82-91

2009

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Targeting LDL: Is lower better and is it safe?

Baillière's best practice & research. Clinical endocrinology & metabolism, 2014-06, Vol.28 (3), p.309-324

2014

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Effect of dalcetrapib plus pravastatin on lipoprotein metabolism and high-density lipoprotein composition and function in dyslipidemic patients: Results of a phase IIb dose-ranging study

The American heart journal, 2012-03, Vol.163 (3), p.515-521.e3

2012

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Colesevelam Hydrochloride: Efficacy and Safety in Pediatric Subjects with Heterozygous Familial Hypercholesterolemia

The Journal of pediatrics, 2010-02, Vol.156 (2), p.231-236.e3

2010

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Efficacy and Tolerability of Fluvastatin XL 80 mg Alone, Ezetimibe Alone, and the Combination of Fluvastatin XL 80 mg With Ezetimibe in Patients With a History of Muscle-Related Side Effects With Other Statins

The American journal of cardiology, 2008-02, Vol.101 (4), p.490-496

2008

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Additional Lipid Lowering Trials Using Surrogate Measurements of Atherosclerosis by Carotid Intima-Media Thickness

Journal of the American College of Cardiology, 2008-12, Vol.52 (25), p.2206-2209

Stein, Evan A., MD, PhD

2008

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Other Therapies for Reducing Low-Density Lipoprotein Cholesterol: Medications in Development

Endocrinology and metabolism clinics of North America, 2009-03, Vol.38 (1), p.99-119

Stein, Evan A., MD, PhD

2009

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Low-Density Lipoprotein Cholesterol Reduction and Prevention of Cardiovascular Disease

Mayo Clinic proceedings, 2009, Vol.84 (4), p.307-309

Stein, Evan A., MD, PhD

2009

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Effects of AMG 145 on Low-Density Lipoprotein Cholesterol Levels

Journal of the American College of Cardiology, 2012-11, Vol.60 (19), p.1888-1898

2012

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Long-Term Efficacy and Safety of Rosuvastatin 40 mg in Patients With Severe Hypercholesterolemia

The American journal of cardiology, 2007-11, Vol.100 (9), p.1387-1396

2007

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Comparison of short-term renal effects and efficacy of rosuvastatin 40 mg and simvastatin 80 mg, followed by assessment of long-term renal effects of rosuvastatin 40 mg, in patients with dyslipidemia

Journal of clinical lipidology, 2007-08, Vol.1 (4), p.287-299

2007

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Long-term treatment with evolocumab added to conventional drug therapy, with or without apheresis, in patients with homozygous familial hypercholesterolaemia: an interim subset analysis of the open-label TAUSSIG study

The lancet. Diabetes & endocrinology, 2017-04, Vol.5 (4), p.280-290

2017

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Effect of a monoclonal antibody to PCSK9, REGN727/SAR236553, to reduce low-density lipoprotein cholesterol in patients with heterozygous familial hypercholesterolaemia on stable statin dose with or without ezetimibe therapy: a phase 2 randomised controlled trial

The Lancet (British edition), 2012-07, Vol.380 (9836), p.29-36

2012

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Efficacy and Safety of Eicosapentaenoic Acid Ethyl Ester (AMR101) Therapy in Statin-Treated Patients With Persistent High Triglycerides (from the ANCHOR Study)

The American journal of cardiology, 2012-10, Vol.110 (7), p.984-992

2012

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Safety and efficacy of dalcetrapib on atherosclerotic disease using novel non-invasive multimodality imaging (dal-PLAQUE): a randomised clinical trial

The Lancet (British edition), 2011-10, Vol.378 (9802), p.1547-1559

2011

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Cancer survival in Australia, Canada, Denmark, Norway, Sweden, and the UK, 1995–2007 (the International Cancer Benchmarking Partnership): an analysis of population-based cancer registry data

The Lancet (British edition), 2011, Vol.377 (9760), p.127-138

2011

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Effects of Maximal Atorvastatin and Rosuvastatin Treatment on Markers of Glucose Homeostasis and Inflammation

The American journal of cardiology, 2011-02, Vol.107 (3), p.387-392

2011

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Reduction in Lipoprotein(a) With PCSK9 Monoclonal Antibody Evolocumab (AMG 145)

Safety and Efficacy of a Monoclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 Serine Protease, SAR236553/REGN727, in Patients With Primary Hypercholesterolemia Receiving Ongoing Stable Atorvastatin Therapy

Effect of Alirocumab, a Monoclonal Proprotein Convertase Subtilisin/Kexin 9 Antibody, on Lipoprotein(a) Concentrations (a Pooled Analysis of 150 mg Every Two Weeks Dosing from Phase 2 Trials)

Effect of Mipomersen, an Apolipoprotein B Synthesis Inhibitor, on Low-Density Lipoprotein Cholesterol in Patients With Familial Hypercholesterolemia

Efficacy and tolerability of adding prescription Omega-3 fatty acids 4 g/d to Simvastatin 40 mg/d in hypertriglyceridemic patients: An 8-week, randomized, double-blind, placebo-controlled study

Efficacy and Safety of Rosuvastatin Therapy for Children With Familial Hypercholesterolemia

Non-statin Treatments for Managing LDL Cholesterol and Their Outcomes

Safety and Tolerability of Dalcetrapib

Targeting LDL: Is lower better and is it safe?

Efficacy and safety of rosuvastatin therapy in children and adolescents with familial hypercholesterolemia: Results from the CHARON study

Effect of dalcetrapib plus pravastatin on lipoprotein metabolism and high-density lipoprotein composition and function in dyslipidemic patients: Results of a phase IIb dose-ranging study

Colesevelam Hydrochloride: Efficacy and Safety in Pediatric Subjects with Heterozygous Familial Hypercholesterolemia

Efficacy and Tolerability of Fluvastatin XL 80 mg Alone, Ezetimibe Alone, and the Combination of Fluvastatin XL 80 mg With Ezetimibe in Patients With a History of Muscle-Related Side Effects With Other Statins

Additional Lipid Lowering Trials Using Surrogate Measurements of Atherosclerosis by Carotid Intima-Media Thickness

Other Therapies for Reducing Low-Density Lipoprotein Cholesterol: Medications in Development

Low-Density Lipoprotein Cholesterol Reduction and Prevention of Cardiovascular Disease

Effects of AMG 145 on Low-Density Lipoprotein Cholesterol Levels

Long-Term Efficacy and Safety of Rosuvastatin 40 mg in Patients With Severe Hypercholesterolemia

Comparison of short-term renal effects and efficacy of rosuvastatin 40 mg and simvastatin 80 mg, followed by assessment of long-term renal effects of rosuvastatin 40 mg, in patients with dyslipidemia

Long-term treatment with evolocumab added to conventional drug therapy, with or without apheresis, in patients with homozygous familial hypercholesterolaemia: an interim subset analysis of the open-label TAUSSIG study

Effect of a monoclonal antibody to PCSK9, REGN727/SAR236553, to reduce low-density lipoprotein cholesterol in patients with heterozygous familial hypercholesterolaemia on stable statin dose with or without ezetimibe therapy: a phase 2 randomised controlled trial

Efficacy and Safety of Eicosapentaenoic Acid Ethyl Ester (AMR101) Therapy in Statin-Treated Patients With Persistent High Triglycerides (from the ANCHOR Study)

Safety and efficacy of dalcetrapib on atherosclerotic disease using novel non-invasive multimodality imaging (dal-PLAQUE): a randomised clinical trial

Cancer survival in Australia, Canada, Denmark, Norway, Sweden, and the UK, 1995–2007 (the International Cancer Benchmarking Partnership): an analysis of population-based cancer registry data

Effects of Maximal Atorvastatin and Rosuvastatin Treatment on Markers of Glucose Homeostasis and Inflammation

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