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In Silico Discovery and Subsequent Characterization of Potent 4R-Tauopathy Positron Emission Tomography Radiotracers

Journal of medicinal chemistry, 2023-08, Vol.66 (15), p.10628-10638

2023

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DECREASED BRAINSTEM AND PUTAMEN SERT BINDING POTENTIAL IN DEPRESSED SUICIDE ATTEMPTERS USING [11C]-ZIENT PET IMAGING

Depression and anxiety, 2013-10, Vol.30 (10), p.902-907

2013

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Radiosynthesis, In Vitro and In Vivo Evaluation of [18F]CBD-2115 as a First-in-Class Radiotracer for Imaging 4R-Tauopathies

ACS chemical neuroscience, 2021-02, Vol.12 (4), p.596-602

2021

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Fluorinated tropanes

Current topics in medicinal chemistry, 2013-04, Vol.13 (8), p.920-935

Stehouwer, Jeffrey S

2013

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Ligand-based design of [18F]OXD-2314 for PET imaging in non-Alzheimer’s disease tauopathies

Nature communications, 2024-06, Vol.15 (1), p.5109-13

2024

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Development of a PET radioligand selective for cerebral amyloid angiopathy

Nuclear medicine and biology, 2021-01, Vol.92, p.85-96

2021

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Erratum to “Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor” [Bioorg. Med. Chem. 23 (2015) 4286–4302]

Bioorganic & medicinal chemistry, 2020-10, Vol.28 (19), p.115660-115660, Article 115660

2020

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Preparation of 1-tosyloxy-4-substituted-2-butenes using Ag(I) salts

Tetrahedron letters, 2015-07, Vol.56 (30), p.4480-4482

2015

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Neurobiological Changes Mediating the Effects of Chronic Fluoxetine on Cocaine Use

Neuropsychopharmacology (New York, N.Y.), 2012-07, Vol.37 (8), p.1816-1824

2012

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Synthesis, binding affinity, radiolabeling, and microPET evaluation of 4-(2-substituted-4-substituted)-8-(dialkylamino)-6-methyl-1-substituted-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-ones as ligands for brain corticotropin-releasing factor type-1 (CRF1) receptors

Bioorganic & medicinal chemistry letters, 2015-11, Vol.25 (22), p.5111-5114

2015

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Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor

Bioorganic & medicinal chemistry, 2015-08, Vol.23 (15), p.4286-4302

2015

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(11) C and (18) F PET radioligands for the serotonin transporter (SERT)

Journal of labelled compounds & radiopharmaceuticals, 2013-03, Vol.56 (3-4), p.114-119

2013

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11C and 18F PET radioligands for the serotonin transporter (SERT)

Journal of labelled compounds & radiopharmaceuticals, 2013-03, Vol.56 (3-4), p.114-119

2013

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Synthesis, Fluorine-18 Radiolabeling, and Biological Evaluation of N-((E)-4-Fluorobut-2-en-1-yl)-2β-carbomethoxy-3β-(4′-halophenyl)nortropanes: Candidate Radioligands for In Vivo Imaging of the Brain Dopamine Transporter with Positron Emission Tomography

Journal of medicinal chemistry, 2010-08, Vol.53 (15), p.5549-5557

2010

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In vivo evaluation of [123 I]mZIENT as a SPECT radioligand for the serotonin transporter

Nuclear medicine and biology, 2012-11, Vol.39 (8), p.1137-1141

2012

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Synthesis, Radiosynthesis, and Biological Evaluation of Carbon-11 and Fluorine-18 Labeled Reboxetine Analogues: Potential Positron Emission Tomography Radioligands for in Vivo Imaging of the Norepinephrine Transporter

Journal of medicinal chemistry, 2009-01, Vol.52 (1), p.62-73

2009

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Fluorine-18 Radiolabeled PET Tracers for Imaging Monoamine Transporters: Dopamine, Serotonin, and Norepinephrine

PET clinics, 2009, Vol.4 (1), p.101-128

2009

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Synthesis, Radiosynthesis, and Biological Evaluation of Fluorine-18-Labeled 2β-Carbo(fluoroalkoxy)-3β-(3′-((Z)-2-haloethenyl)phenyl)nortropanes: Candidate Radioligands for In Vivo Imaging of the Serotonin Transporter with Positron Emission Tomography

Journal of medicinal chemistry, 2008-12, Vol.51 (24), p.7788-7799

2008

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Biodistribution and dosimetry of 123I-mZIENT: a novel ligand for imaging serotonin transporters

European journal of nuclear medicine and molecular imaging, 2012-05, Vol.39 (5), p.786-791

2012

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Synthesis and in Vivo Evaluation of Fluorine-18 and Iodine-123 Labeled 2β-Carbo(2-fluoroethoxy)-3β-(4‘-((Z)-2-iodoethenyl)phenyl)nortropane as a Candidate Serotonin Transporter Imaging Agent

Journal of medicinal chemistry, 2007-09, Vol.50 (19), p.4553-4560

2007

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Formation of a Macrobicyclic Tris(disulfide) by Molecular Self-Assembly

Journal of organic chemistry, 1999-01, Vol.64 (2), p.334-335

1999

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Synthesis, Radiosynthesis, and Biological Evaluation of Carbon-11 Labeled 2β-Carbomethoxy-3β-(3‘-((Z)-2-haloethenyl)phenyl)nortropanes: Candidate Radioligands for in Vivo Imaging of the Serotonin Transporter with Positron Emission Tomography

Journal of medicinal chemistry, 2006-11, Vol.49 (23), p.6760-6767

2006

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Synthesis, in vitro characterization, and radiolabeling of reboxetine analogs as potential PET radioligands for imaging the norepinephrine transporter

Bioorganic & medicinal chemistry, 2008-01, Vol.16 (2), p.783-793

2008

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Ligand-based design of 18FOXD-2314 for PET imaging in non-Alzheimer's disease tauopathies

Nature communications, 2024-06, Vol.15 (1), p.5109

2024

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Synthesis, Radiosynthesis, and Biological Evaluation of Carbon-11 and Fluorine-18 (N-Fluoroalkyl) Labeled 2β-Carbomethoxy-3β-(4'-(3-furyl)phenyl)tropanes and -nortropanes: Candidate Radioligands for in Vivo Imaging of the Serotonin Transporter with Positron Emission Tomography

Journal of medicinal chemistry, 2005-11, Vol.48 (22), p.7080-7083

2005

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In Silico Discovery and Subsequent Characterization of Potent 4R-Tauopathy Positron Emission Tomography Radiotracers

DECREASED BRAINSTEM AND PUTAMEN SERT BINDING POTENTIAL IN DEPRESSED SUICIDE ATTEMPTERS USING [11C]-ZIENT PET IMAGING

Radiosynthesis, In Vitro and In Vivo Evaluation of [18F]CBD-2115 as a First-in-Class Radiotracer for Imaging 4R-Tauopathies

Fluorinated tropanes

Ligand-based design of [18F]OXD-2314 for PET imaging in non-Alzheimer’s disease tauopathies

Development of a PET radioligand selective for cerebral amyloid angiopathy

Erratum to “Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor” [Bioorg. Med. Chem. 23 (2015) 4286–4302]

Preparation of 1-tosyloxy-4-substituted-2-butenes using Ag(I) salts

Neurobiological Changes Mediating the Effects of Chronic Fluoxetine on Cocaine Use

Synthesis, binding affinity, radiolabeling, and microPET evaluation of 4-(2-substituted-4-substituted)-8-(dialkylamino)-6-methyl-1-substituted-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-ones as ligands for brain corticotropin-releasing factor type-1 (CRF1) receptors

Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor

(11) C and (18) F PET radioligands for the serotonin transporter (SERT)

11C and 18F PET radioligands for the serotonin transporter (SERT)

Synthesis, Fluorine-18 Radiolabeling, and Biological Evaluation of N-((E)-4-Fluorobut-2-en-1-yl)-2β-carbomethoxy-3β-(4′-halophenyl)nortropanes: Candidate Radioligands for In Vivo Imaging of the Brain Dopamine Transporter with Positron Emission Tomography

In vivo evaluation of [123 I]mZIENT as a SPECT radioligand for the serotonin transporter

Synthesis, Radiosynthesis, and Biological Evaluation of Carbon-11 and Fluorine-18 Labeled Reboxetine Analogues: Potential Positron Emission Tomography Radioligands for in Vivo Imaging of the Norepinephrine Transporter

Fluorine-18 Radiolabeled PET Tracers for Imaging Monoamine Transporters: Dopamine, Serotonin, and Norepinephrine

Synthesis, Radiosynthesis, and Biological Evaluation of Fluorine-18-Labeled 2β-Carbo(fluoroalkoxy)-3β-(3′-((Z)-2-haloethenyl)phenyl)nortropanes: Candidate Radioligands for In Vivo Imaging of the Serotonin Transporter with Positron Emission Tomography

Biodistribution and dosimetry of 123I-mZIENT: a novel ligand for imaging serotonin transporters

Synthesis and in Vivo Evaluation of Fluorine-18 and Iodine-123 Labeled 2β-Carbo(2-fluoroethoxy)-3β-(4‘-((Z)-2-iodoethenyl)phenyl)nortropane as a Candidate Serotonin Transporter Imaging Agent

Formation of a Macrobicyclic Tris(disulfide) by Molecular Self-Assembly

Synthesis, Radiosynthesis, and Biological Evaluation of Carbon-11 Labeled 2β-Carbomethoxy-3β-(3‘-((Z)-2-haloethenyl)phenyl)nortropanes: Candidate Radioligands for in Vivo Imaging of the Serotonin Transporter with Positron Emission Tomography

Synthesis, in vitro characterization, and radiolabeling of reboxetine analogs as potential PET radioligands for imaging the norepinephrine transporter

Ligand-based design of 18FOXD-2314 for PET imaging in non-Alzheimer's disease tauopathies

Synthesis, Radiosynthesis, and Biological Evaluation of Carbon-11 and Fluorine-18 (N-Fluoroalkyl) Labeled 2β-Carbomethoxy-3β-(4'-(3-furyl)phenyl)tropanes and -nortropanes: Candidate Radioligands for in Vivo Imaging of the Serotonin Transporter with Positron Emission Tomography

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