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Development of Fluorescent Probes that Target Serotonin 5-HT2B Receptors

Scientific reports, 2017-09, Vol.7 (1), p.1-16, Article 10765

2017

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How Do Molecular Dynamics Data Complement Static Structural Data of GPCRs

International journal of molecular sciences, 2020-08, Vol.21 (16), p.5933

2020

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Protein-Protein Docking in Drug Design and Discovery

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1762, p.285

2018

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Ligand with Two Modes of Interaction with the Dopamine D 2 Receptor–An Induced-Fit Mechanism of Insurmountable Antagonism

ACS chemical neuroscience, 2020-10, Vol.11 (19), p.3130-3143

2020

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Ligand with Two Modes of Interaction with the Dopamine D2 Receptor–An Induced-Fit Mechanism of Insurmountable Antagonism

ACS chemical neuroscience, 2020-10, Vol.11 (19), p.3130-3143

2020

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Glutamate, GABA, and Presynaptic Markers Involved in Neurotransmission Are Differently Affected by Age in Distinct Mouse Brain Regions

ACS chemical neuroscience, 2019-11, Vol.10 (11), p.4449-4461

2019

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GPCRmd uncovers the dynamics of the 3D-GPCRome

Nature methods, 2020-08, Vol.17 (8), p.777-787

2020

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Do they make a good match? Molecular dynamics studies on CALB-catalyzed esterification of 3-phenylpropionic and cinnamic acids

Archives of biochemistry and biophysics, 2023-12, Vol.750, p.109807-109807, Article 109807

2023

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A highly conserved δ‐opioid receptor region determines RGS4 interaction

The FEBS journal, 2020-02, Vol.287 (4), p.736-748

2020

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Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody

Nature communications, 2022-08, Vol.13 (1), p.4634-4634, Article 4634

2022

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Dopamine D2 Receptor Agonist Binding Kinetics—Role of a Conserved Serine Residue

International journal of molecular sciences, 2021-04, Vol.22 (8), p.4078

2021

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G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits

Nature communications, 2024-05, Vol.15 (1), p.4307-15, Article 4307

2024

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Entrectinib-A SARS-CoV-2 Inhibitor in Human Lung Tissue (HLT) Cells

International journal of molecular sciences, 2021-12, Vol.22 (24), p.13592

2021

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Challenges and Opportunities in Drug Discovery of Biased Ligands

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1705, p.321

2018

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Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists

Bioorganic & medicinal chemistry, 2018-07, Vol.26 (12), p.3580-3587

2018

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Ligand entry pathways control the chemical space recognized by GPR183

Chemical science (Cambridge), 2023-10, Vol.14 (39), p.1671-1683

2023

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Dopamine D 2 Receptor Agonist Binding Kinetics-Role of a Conserved Serine Residue

International journal of molecular sciences, 2021-04, Vol.22 (8)

2021

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Key phosphorylation sites in GPCRs orchestrate the contribution of β‐Arrestin 1 in ERK1/2 activation

EMBO reports, 2020-09, Vol.21 (9), p.e49886-n/a

2020

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Relevance of G protein‐coupled receptor (GPCR) dynamics for receptor activation, signalling bias and allosteric modulation

British journal of pharmacology, 2024-07

2024

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Development of Fluorescent Probes that Target Serotonin 5-HT 2B Receptors

Scientific reports, 2017-09, Vol.7 (1), p.10765

2017

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Palmitoylation of cysteine 415 of CB1 receptor affects ligand-stimulated internalization and selective interaction with membrane cholesterol and caveolin 1

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2017-05, Vol.1862 (5), p.523-532

2017

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Mechanistic insights into dopaminergic and serotonergic neurotransmission - concerted interactions with helices 5 and 6 drive the functional outcome

Chemical science (Cambridge), 2021-08, Vol.12 (33), p.199-113

2021

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Phosphorylation patterns in the AT1R C-terminal tail specify distinct downstream signaling pathways

Science signaling, 2024-08, Vol.17 (849)

2024

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Phosphorylation barcodes direct biased chemokine signaling at CXCR3

Cell chemical biology, 2023-04, Vol.30 (4), p.362-382.e8

2023

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Development of Fluorescent Probes that Target Serotonin 5-HT2B Receptors

How Do Molecular Dynamics Data Complement Static Structural Data of GPCRs

Protein-Protein Docking in Drug Design and Discovery

Ligand with Two Modes of Interaction with the Dopamine D 2 Receptor–An Induced-Fit Mechanism of Insurmountable Antagonism

Ligand with Two Modes of Interaction with the Dopamine D2 Receptor–An Induced-Fit Mechanism of Insurmountable Antagonism

Glutamate, GABA, and Presynaptic Markers Involved in Neurotransmission Are Differently Affected by Age in Distinct Mouse Brain Regions

GPCRmd uncovers the dynamics of the 3D-GPCRome

Do they make a good match? Molecular dynamics studies on CALB-catalyzed esterification of 3-phenylpropionic and cinnamic acids

A highly conserved δ‐opioid receptor region determines RGS4 interaction

Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody

Dopamine D2 Receptor Agonist Binding Kinetics—Role of a Conserved Serine Residue

G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits

Entrectinib-A SARS-CoV-2 Inhibitor in Human Lung Tissue (HLT) Cells

Challenges and Opportunities in Drug Discovery of Biased Ligands

Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists

Ligand entry pathways control the chemical space recognized by GPR183

Dopamine D 2 Receptor Agonist Binding Kinetics-Role of a Conserved Serine Residue

Key phosphorylation sites in GPCRs orchestrate the contribution of β‐Arrestin 1 in ERK1/2 activation

Relevance of G protein‐coupled receptor (GPCR) dynamics for receptor activation, signalling bias and allosteric modulation

Development of Fluorescent Probes that Target Serotonin 5-HT 2B Receptors

Palmitoylation of cysteine 415 of CB1 receptor affects ligand-stimulated internalization and selective interaction with membrane cholesterol and caveolin 1

Altered desensitization and internalization patterns of rodent versus human glucose‐dependent insulinotropic polypeptide (GIP) receptors. An important drug discovery challenge

Mechanistic insights into dopaminergic and serotonergic neurotransmission - concerted interactions with helices 5 and 6 drive the functional outcome

Phosphorylation patterns in the AT1R C-terminal tail specify distinct downstream signaling pathways

Phosphorylation barcodes direct biased chemokine signaling at CXCR3

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