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Discovery of 5-substituent-N-arylbenzamide derivatives as potent, selective and orally bioavailable LRRK2 inhibitors
Bioorganic & medicinal chemistry letters, 2017-09, Vol.27 (17), p.4034-4038
2017
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Synthesis, pharmacophore modeling and in vitro activity of 10,11-dihydrodibenzo[b,f]oxepine-4-carboxamide derivatives as novel and potent antagonists of the prostaglandin EP₄ receptor
Bioorganic & medicinal chemistry letters, 2011-11, Vol.21 (21), p.6336-6340
2011
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Discovery of 4-ethoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amines as potent, selective and orally bioavailable LRRK2 inhibitors
Bioorganic & medicinal chemistry letters, 2018-05, Vol.28 (9), p.1615-1620
2018
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5-Substituted-N-pyridazinylbenzamides as potent and selective LRRK2 inhibitors: Improved brain unbound fraction enables efficacy
Bioorganic & medicinal chemistry letters, 2019-01, Vol.29 (2), p.212-215
2019
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A High-Throughput Screen to Identify LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease Using RapidFire Mass Spectrometry
Journal of biomolecular screening, 2016-02, Vol.21 (2), p.145-155
2016
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Prostaglandin EP4 antagonists
Pharmaceutical patent analyst, 2013-05, Vol.2 (3), p.387-397
2013
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Synthesis and Conformational Studies of 3'-(2'-Aminoborane-2'-deoxyuridyl)-5'-thymidilyl Hydrogen Phosphate to be Used in the Construction of Oligonucleotide Sequences
Heterocycles, 2003-12, Vol.61 (1), p.403
2003
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Prostaglandin EP 4 Antagonists
Pharmaceutical patent analyst, 2013-05, Vol.2 (3), p.387-397
2013
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Synthesis and Structure–Activity Relationship Studies in Translocator Protein Ligands Based on a Pyrazolo[3,4-b]quinoline Scaffold
Journal of medicinal chemistry, 2011-10, Vol.54 (20), p.7165-7175
2011
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Discovery, synthesis, selectivity modulation and DMPK characterization of 5-azaspiro[2.4]heptanes as potent orexin receptor antagonists
Bioorganic & medicinal chemistry letters, 2013-05, Vol.23 (9), p.2653-2658
2013
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Design, Synthesis, and Preliminary Biological Evaluation of Pyrrolo[3,4-c]quinolin-1-one and Oxoisoindoline Derivatives as Aggrecanase Inhibitors
ChemMedChem, 2010-05, Vol.5 (5), p.739-748
2010
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Synthesis, pharmacophore modeling and in vitro activity of 10,11-dihydrodibenzo[b,f]oxepine-4-carboxamide derivatives as novel and potent antagonists of the prostaglandin EP sub(4 receptor)
Bioorganic & medicinal chemistry letters, 2011-11, Vol.21 (21), p.6336-6340
2011
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Synthesis, pharmacophore modeling and in vitro activity of 10,11-dihydrodibenzo[ b, f]oxepine-4-carboxamide derivatives as novel and potent antagonists of the prostaglandin EP 4 receptor
Bioorganic & medicinal chemistry letters, 2011, Vol.21 (21), p.6336-6340
2011
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ChemInform Abstract: Synthesis, Pharmacophore Modeling and in vitro Activity of 10,11‐Dihydrodibenzo[b,f]oxepine‐4‐carboxamide Derivatives as Novel and Potent Antagonists of the Prostaglandin EP 4 Receptor
ChemInform, 2012-03, Vol.43 (10)
2012
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ChemInform Abstract: Synthesis, Pharmacophore Modeling and in vitro Activity of 10,11-Dihydrodibenzo[b,f]oxepine-4-carboxamide Derivatives as Novel and Potent Antagonists of the Prostaglandin EP4 Receptor
ChemInform, 2012-03, Vol.43 (10), p.no-no
2012
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Efficacy of a new technique - INtubate-RECruit-SURfactant-Extubate - "IN-REC-SUR-E" - in preterm neonates with respiratory distress syndrome: study protocol for a randomized controlled trial
Trials, 2016-08, Vol.17 (1), p.414-414, Article 414
2016
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Detection of soluble interleukin‐2 receptor and interleukin‐10 in the serum of patients with aggressive non‐Hodgkin's lymphoma.Identification of a subset at high risk of treatment failure
Cancer, 1994-09, Vol.74 (6), p.1792-1800
1994
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Prognostic value of serum IL‐10 and soluble IL‐2 receptor levels in aggressive non‐Hodgkin's lymphoma
British journal of haematology, 1994-12, Vol.88 (4), p.770-777
1994
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Clinical implications of cytokine and soluble receptor measurements in patients with newly-diagnosed aggressive non-Hodgkin's lymphoma
European journal of haematology, 1995-01, Vol.54 (1), p.9-17
1995
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