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Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab

Angiogenesis (London), 2012-06, Vol.15 (2), p.171-185

2012

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Vascular-specific growth factors and blood vessel formation

Nature (London), 2000-09, Vol.407 (6801), p.242-248

2000

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Effect of VEGF trap on normal retinal vascular development and oxygen-induced retinopathy in the dog

Investigative ophthalmology & visual science, 2011-06, Vol.52 (7), p.4039-4047

2011

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The Dll4/Notch pathway controls postangiogenic blood vessel remodeling and regression by modulating vasoconstriction and blood flow

Blood, 2011-06, Vol.117 (24), p.6728-6737

2011

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VEGF-Trap: A VEGF Blocker with Potent Antitumor Effects

Proceedings of the National Academy of Sciences - PNAS, 2002-08, Vol.99 (17), p.11393-11398

2002

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VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade

Proceedings of the National Academy of Sciences - PNAS, 2007-11, Vol.104 (47), p.18363-18370

2007

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Angiopoietin-2 Is Required for Postnatal Angiogenesis and Lymphatic Patterning, and Only the Latter Role Is Rescued by Angiopoietin-1

Developmental cell, 2002-09, Vol.3 (3), p.411-423

2002

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A subretinal matrigel rat choroidal neovascularization (CNV) model and inhibition of CNV and associated inflammation and fibrosis by VEGF trap

Investigative ophthalmology & visual science, 2010-11, Vol.51 (11), p.6009-6017

2010

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Genetic Deletion of Ghrelin Does Not Decrease Food Intake but Influences Metabolic Fuel Preference

Proceedings of the National Academy of Sciences - PNAS, 2004-05, Vol.101 (21), p.8227-8232

2004

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Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity

Nature medicine, 2005-02, Vol.11 (2), p.199-205

2005

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Retinal Vascular Endothelial Growth Factor Induces Intercellular Adhesion Molecule-1 and Endothelial Nitric Oxide Synthase Expression and Initiates Early Diabetic Retinal Leukocyte Adhesion in Vivo

The American journal of pathology, 2002-02, Vol.160 (2), p.501-509

2002

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Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells

The Journal of clinical investigation, 2002-12, Vol.110 (11), p.1619-1628

2002

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Suppression of Diabetic Retinopathy with Angiopoietin-1

The American journal of pathology, 2002-05, Vol.160 (5), p.1683-1693

2002

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Inhibition of Delta-Like Ligand 4 Induces Luteal Hypervascularization Followed by Functional and Structural Luteolysis in the Primate Ovary

Endocrinology (Philadelphia), 2012-04, Vol.153 (4), p.1972-1983

2012

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Anterograde transport of brain-derived neurotrophic factor and its role in the brain

Nature (London), 1997-10, Vol.389 (6653), p.856-860

1997

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Agouti-related protein-deficient mice display an age-related lean phenotype

Cell metabolism, 2005-12, Vol.2 (6), p.421-427

2005

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Ciliary Neurotrophic Factor and Stress Stimuli Activate the Jak-STAT Pathway in Retinal Neurons and Glia

The Journal of neuroscience, 2000-06, Vol.20 (11), p.4081-4090

2000

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Vascular endothelial growth factor regulates reendothelialization and neointima formation in a mouse model of arterial injury

Circulation (New York, N.Y.), 2004-10, Vol.110 (16), p.2430-2435

2004

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Vascular Apoptosis and Involution in Gliomas Precede Neovascularization: A Novel Concept for Glioma Growth and Angiogenesis

Laboratory investigation, 2000-06, Vol.80 (6), p.837-849

2000

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The Role of Vascular Endothelial Growth Factor and Estradiol in the Regulation of Endometrial Angiogenesis and Cell Proliferation in the Marmoset

Endocrinology (Philadelphia), 2008-09, Vol.149 (9), p.4413-4420

2008

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Vascular Endothelial Growth Factor Mediates the Estrogen-Induced Breakdown of Tight Junctions between and Increase in Proliferation of Microvessel Endothelial Cells in the Baboon Endometrium

Endocrinology (Philadelphia), 2008-12, Vol.149 (12), p.6076-6083

2008

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VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment

The Journal of clinical investigation, 2004-04, Vol.113 (7), p.1040-1050

2004

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Administration of vascular endothelial growth factor Trap during the ‘post-angiogenic’ period of the luteal phase causes rapid functional luteolysis and selective endothelial cell death in the marmoset

Reproduction (Cambridge, England), 2006-10, Vol.132 (4), p.589-600

2006

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VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment

The Journal of clinical investigation, 2004-04, Vol.113 (7), p.1040-1050

2004

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A liver Hif-2α–Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition

Nature Medicine, 2013-10, Vol.19 (10), p.1331-1337

2013

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Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab

Vascular-specific growth factors and blood vessel formation

Effect of VEGF trap on normal retinal vascular development and oxygen-induced retinopathy in the dog

The Dll4/Notch pathway controls postangiogenic blood vessel remodeling and regression by modulating vasoconstriction and blood flow

VEGF-Trap: A VEGF Blocker with Potent Antitumor Effects

VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade

Angiopoietin-2 Is Required for Postnatal Angiogenesis and Lymphatic Patterning, and Only the Latter Role Is Rescued by Angiopoietin-1

A subretinal matrigel rat choroidal neovascularization (CNV) model and inhibition of CNV and associated inflammation and fibrosis by VEGF trap

Genetic Deletion of Ghrelin Does Not Decrease Food Intake but Influences Metabolic Fuel Preference

Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity

Retinal Vascular Endothelial Growth Factor Induces Intercellular Adhesion Molecule-1 and Endothelial Nitric Oxide Synthase Expression and Initiates Early Diabetic Retinal Leukocyte Adhesion in Vivo

Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells

Suppression of Diabetic Retinopathy with Angiopoietin-1

Inhibition of Delta-Like Ligand 4 Induces Luteal Hypervascularization Followed by Functional and Structural Luteolysis in the Primate Ovary

Anterograde transport of brain-derived neurotrophic factor and its role in the brain

Agouti-related protein-deficient mice display an age-related lean phenotype

Ciliary Neurotrophic Factor and Stress Stimuli Activate the Jak-STAT Pathway in Retinal Neurons and Glia

Vascular endothelial growth factor regulates reendothelialization and neointima formation in a mouse model of arterial injury

Vascular Apoptosis and Involution in Gliomas Precede Neovascularization: A Novel Concept for Glioma Growth and Angiogenesis

The Role of Vascular Endothelial Growth Factor and Estradiol in the Regulation of Endometrial Angiogenesis and Cell Proliferation in the Marmoset

Vascular Endothelial Growth Factor Mediates the Estrogen-Induced Breakdown of Tight Junctions between and Increase in Proliferation of Microvessel Endothelial Cells in the Baboon Endometrium

VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment

Administration of vascular endothelial growth factor Trap during the ‘post-angiogenic’ period of the luteal phase causes rapid functional luteolysis and selective endothelial cell death in the marmoset

VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment

A liver Hif-2α–Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition

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