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From arylamine N-acetyltransferase to folate-dependent acetyl CoA hydrolase: impact of folic acid on the activity of (HUMAN)NAT1 and its homologue (MOUSE)NAT2

PloS one, 2014-05, Vol.9 (5), p.e96370

2014

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Modeling human cytochrome P450 2D6 metabolism and drug-drug interaction by a novel panel of knockout and humanized mouse lines

Molecular pharmacology, 2012-01, Vol.81 (1), p.63-72

2012

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Through a glass, darkly? HepaRG and HepG2 cells as models of human phase I drug metabolism

Drug metabolism reviews, 2022-01, Vol.54 (1), p.46-62

2022

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PXR and CAR: Nuclear Receptors which Play a Pivotal Role in Drug Disposition and Chemical Toxicity

Drug metabolism reviews, 2006-01, Vol.38 (3), p.515-597

2006

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Update on the pharmacogenetics of NATs: structural considerations

Pharmacogenomics, 2008-11, Vol.9 (11), p.1673-1693

2008

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Cytochrome b5 is a major determinant of human cytochrome P450 CYP2D6 and CYP3A4 activity in vivo

Molecular pharmacology, 2015-04, Vol.87 (4), p.733

2015

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Drug transporters: Gatekeepers controlling access of xenobiotics to the cellular interior

Drug metabolism reviews, 2009, Vol.41 (1), p.27-65

2009

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Lack of evidence for metabolism of p-phenylenediamine by human hepatic cytochrome P450 enzymes

Toxicology (Amsterdam), 2005-06, Vol.210 (2), p.147-157

2005

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Evidence that the capacity of nongenotoxic carcinogens to induce oxidative stress is subject to marked variability

Toxicological sciences, 2015-05, Vol.145 (1), p.138-148

2015

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Dermal penetration and metabolism of p-aminophenol and p-phenylenediamine: Application of the EpiDerm™ human reconstructed epidermis model

Toxicology letters, 2009-07, Vol.188 (2), p.119-129

2009

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Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding

BMC pharmacology & toxicology, 2014-11, Vol.15 (1), p.68-68, Article 68

2014

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Antitumor Benzothiazoles. 7. Synthesis of 2-(4-Acylaminophenyl)benzothiazoles and Investigations into the Role of Acetylation in the Antitumor Activities of the Parent Amines

Journal of medicinal chemistry, 1999-02, Vol.42 (3), p.381-392

1999

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Molecular aspects of chemical carcinogenesis: The roles of oncogenes and tumour suppressor genes

Toxicology, 1995-02, Vol.96 (3), p.173-194

Stanley, Lesley A.

1995

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Cytochrome b 5 Is a Major Determinant of Human Cytochrome P450 CYP2D6 and CYP3A4 Activity In Vivo

Molecular pharmacology, 2015-04, Vol.87 (4), p.733-739

2015

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Association of tamoxifen biliary excretion rate with prior tamoxifen exposure and increased mdr1b expression

Biochemical pharmacology, 2000-07, Vol.60 (2), p.233-239

2000

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Proto-oncogene activation in liver tumors of hepatocarcinogenesis-resistant strains of mice

Carcinogenesis (New York), 1992-12, Vol.13 (12), p.2427-2433

1992

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Potentiation and suppression of mouse liver cytochrome P‐450 isozymes during the acute‐phase response induced by bacterial endotoxin

European journal of biochemistry, 1988-05, Vol.174 (1), p.31-36

1988

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Immunochemical detection of arylamine N-acetyltransferase in normal and neoplastic bladder

The journal of histochemistry and cytochemistry, 1996-09, Vol.44 (9), p.1059-1067

1996

Volltextzugriff (PDF)

Xenogenetics in multifactorial disease susceptibility

Trends in genetics, 1995-12, Vol.11 (12), p.509-512

1995

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Differential effects of recombinant interferon α on constitutive and inducible cytochrome P450 isozymes in mouse liver

Biochemical pharmacology, 1991-07, Vol.42 (2), p.311-320

1991

Volltextzugriff (PDF)

Immunotoxic side-effects of drug therapy

Drug safety, 1990-05, Vol.5 (3), p.168-178

1990

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Cytochrome P‐450 induction in human lung tumor‐derived cell lines

European journal of biochemistry, 1992-09, Vol.208 (2), p.521-529

1992

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Cytochrome P-450 induction in human lung tumor-derived cell lines : characterisation and effects of inflammatory mediators

European journal of biochemistry, 1992-09, Vol.208 (2), p.521-529

1992

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Localization of polymorphic N-acetyltransferase (NAT2) in tissues of inbred mice

Pharmacogenetics (London), 1997-04, Vol.7 (2), p.121-130

1997

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Implications of Time on Donor Behavior and Processes in Relation to Localization

Negotiation journal, 2023-10, Vol.39 (4), p.455-480

2023

Volltextzugriff (PDF)

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From arylamine N-acetyltransferase to folate-dependent acetyl CoA hydrolase: impact of folic acid on the activity of (HUMAN)NAT1 and its homologue (MOUSE)NAT2

Modeling human cytochrome P450 2D6 metabolism and drug-drug interaction by a novel panel of knockout and humanized mouse lines

Through a glass, darkly? HepaRG and HepG2 cells as models of human phase I drug metabolism

PXR and CAR: Nuclear Receptors which Play a Pivotal Role in Drug Disposition and Chemical Toxicity

Update on the pharmacogenetics of NATs: structural considerations

Cytochrome b5 is a major determinant of human cytochrome P450 CYP2D6 and CYP3A4 activity in vivo

Drug transporters: Gatekeepers controlling access of xenobiotics to the cellular interior

Lack of evidence for metabolism of p-phenylenediamine by human hepatic cytochrome P450 enzymes

Evidence that the capacity of nongenotoxic carcinogens to induce oxidative stress is subject to marked variability

Dermal penetration and metabolism of p-aminophenol and p-phenylenediamine: Application of the EpiDerm™ human reconstructed epidermis model

Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding

Antitumor Benzothiazoles. 7. Synthesis of 2-(4-Acylaminophenyl)benzothiazoles and Investigations into the Role of Acetylation in the Antitumor Activities of the Parent Amines

Molecular aspects of chemical carcinogenesis: The roles of oncogenes and tumour suppressor genes

Cytochrome b 5 Is a Major Determinant of Human Cytochrome P450 CYP2D6 and CYP3A4 Activity In Vivo

Association of tamoxifen biliary excretion rate with prior tamoxifen exposure and increased mdr1b expression

Proto-oncogene activation in liver tumors of hepatocarcinogenesis-resistant strains of mice

Potentiation and suppression of mouse liver cytochrome P‐450 isozymes during the acute‐phase response induced by bacterial endotoxin

Immunochemical detection of arylamine N-acetyltransferase in normal and neoplastic bladder

Xenogenetics in multifactorial disease susceptibility

Differential effects of recombinant interferon α on constitutive and inducible cytochrome P450 isozymes in mouse liver

Immunotoxic side-effects of drug therapy

Cytochrome P‐450 induction in human lung tumor‐derived cell lines

Cytochrome P-450 induction in human lung tumor-derived cell lines : characterisation and effects of inflammatory mediators

Localization of polymorphic N-acetyltransferase (NAT2) in tissues of inbred mice

Implications of Time on Donor Behavior and Processes in Relation to Localization

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