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Mitochondria-associated endoplasmic reticulum membranes (MAMs) and their role in glaucomatous retinal ganglion cell degeneration-a mini review

Frontiers in neuroscience, 2023-05, Vol.17, p.1198343-1198343

2023

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Modulating mitochondrial calcium channels (TRPM2/MCU/NCX) as a therapeutic strategy for neurodegenerative disorders

Frontiers in neuroscience, 2023-10, Vol.17, p.1202167-1202167

2023

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Role of mitophagy in ocular neurodegeneration

Frontiers in neuroscience, 2023-10, Vol.17, p.1299552-1299552

2023

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Modulation of Mitochondrial Metabolic Parameters and Antioxidant Enzymes in Healthy and Glaucomatous Trabecular Meshwork Cells with Hybrid Small Molecule SA-2

International journal of molecular sciences, 2023-07, Vol.24 (14), p.11557

2023

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Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma

Cell death & disease, 2022-11, Vol.13 (11), p.958-958, Article 958

2022

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Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice

International journal of molecular sciences, 2020-03, Vol.21 (5), p.1795

2020

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Elimination of autofluorescence background from fluorescence tissue images by use of time-gated detection and the AzaDiOxaTriAngulenium (ADOTA) fluorophore

Analytical and bioanalytical chemistry, 2013-02, Vol.405 (6), p.2065-2075

2013

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Neuroprotective effects of inhibitors of Acid-Sensing ion channels (ASICs) in optic nerve crush model in rodents

Current eye research, 2018-01, Vol.43 (1), p.84-95

2018

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Endothelin B receptors contribute to retinal ganglion cell loss in a rat model of glaucoma

PloS one, 2012-08, Vol.7 (8), p.e43199-e43199

2012

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Neuroprotection of Rodent and Human Retinal Ganglion Cells In Vitro/Ex Vivo by the Hybrid Small Molecule SA-2

Cells (Basel, Switzerland), 2022-11, Vol.11 (23), p.3741

2022

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Mechanisms contributing to inhibition of retinal ganglion cell death by cell permeable peptain-1 under glaucomatous stress

Cell death discovery, 2024-06, Vol.10 (1), p.305-12, Article 305

2024

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Involvement of AP-1 and C/EBPβ in upregulation of endothelin B (ETB) receptor expression in a rodent model of glaucoma

PloS one, 2013-11, Vol.8 (11), p.e79183-e79183

2013

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The endothelin receptor antagonist macitentan ameliorates endothelin-mediated vasoconstriction and promotes the survival of retinal ganglion cells in rats

Frontiers in ophthalmology, 2023, Vol.3

2023

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Targets of Neuroprotection in Glaucoma

Journal of ocular pharmacology and therapeutics, 2018-03, Vol.34 (1-2), p.85-106

2018

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Involvement of c-Jun N-terminal kinase 2 (JNK2) in Endothelin-1 (ET-1) Mediated Neurodegeneration of Retinal Ganglion Cells

Investigative ophthalmology & visual science, 2021-05, Vol.62 (6), p.13-13

2021

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Endothelin-1 Mediated Decrease in Mitochondrial Gene Expression and Bioenergetics Contribute to Neurodegeneration of Retinal Ganglion Cells

Scientific reports, 2020-02, Vol.10 (1), p.3571-3571, Article 3571

2020

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CSP7 Protects Alveolar Epithelial Cells by Targeting p53 -Fibrinolytic Pathways During Lung Injuries

American journal of respiratory cell and molecular biology, 2024-09

2024

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Oral administration of a dual ETA/ETB receptor antagonist promotes neuroprotection in a rodent model of glaucoma

Molecular vision, 2022, Vol.28, p.165-177

2022

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Hybrid Compound SA-2 is Neuroprotective in Animal Models of Retinal Ganglion Cell Death

Investigative ophthalmology & visual science, 2019-07, Vol.60 (8), p.3064

2019

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Bcl-2, Bcl-xL, and p-AKT are involved in neuroprotective effects of transcription factor Brn3b in an ocular hypertension rat model of glaucoma

Molecular vision, 2016-08, Vol.22, p.1048-1061

2016

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Nanoencapsulated hybrid compound SA-2 with long-lasting intraocular pressure-lowering activity in rodent eyes

Molecular vision, 2021, Vol.27, p.37-49

2021

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Upregulation of the endothelin A (ET A ) receptor and its association with neurodegeneration in a rodent model of glaucoma

BMC neuroscience, 2017-03, Vol.18 (1), p.27-27, Article 27

2017

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Neuroprotective effects of curcumin on endothelin-1 mediated cell death in hippocampal neurons

Nutritional neuroscience, 2017-05, Vol.20 (5), p.273-283

2017

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Design and synthesis of novel hybrid sydnonimine and prodrug useful for glaucomatous optic neuropathy

Bioorganic & medicinal chemistry letters, 2016-03, Vol.26 (5), p.1490-1494

2016

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Sigma-1 receptor stimulation attenuates calcium influx through activated L-type Voltage Gated Calcium Channels in purified retinal ganglion cells

Experimental eye research, 2013-02, Vol.107, p.21-31

2013

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Mitochondria-associated endoplasmic reticulum membranes (MAMs) and their role in glaucomatous retinal ganglion cell degeneration-a mini review

Modulating mitochondrial calcium channels (TRPM2/MCU/NCX) as a therapeutic strategy for neurodegenerative disorders

Role of mitophagy in ocular neurodegeneration

Modulation of Mitochondrial Metabolic Parameters and Antioxidant Enzymes in Healthy and Glaucomatous Trabecular Meshwork Cells with Hybrid Small Molecule SA-2

Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma

Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice

Elimination of autofluorescence background from fluorescence tissue images by use of time-gated detection and the AzaDiOxaTriAngulenium (ADOTA) fluorophore

Neuroprotective effects of inhibitors of Acid-Sensing ion channels (ASICs) in optic nerve crush model in rodents

Endothelin B receptors contribute to retinal ganglion cell loss in a rat model of glaucoma

Neuroprotection of Rodent and Human Retinal Ganglion Cells In Vitro/Ex Vivo by the Hybrid Small Molecule SA-2

Mechanisms contributing to inhibition of retinal ganglion cell death by cell permeable peptain-1 under glaucomatous stress

Involvement of AP-1 and C/EBPβ in upregulation of endothelin B (ETB) receptor expression in a rodent model of glaucoma

The endothelin receptor antagonist macitentan ameliorates endothelin-mediated vasoconstriction and promotes the survival of retinal ganglion cells in rats

Targets of Neuroprotection in Glaucoma

Involvement of c-Jun N-terminal kinase 2 (JNK2) in Endothelin-1 (ET-1) Mediated Neurodegeneration of Retinal Ganglion Cells

Endothelin-1 Mediated Decrease in Mitochondrial Gene Expression and Bioenergetics Contribute to Neurodegeneration of Retinal Ganglion Cells

CSP7 Protects Alveolar Epithelial Cells by Targeting p53 -Fibrinolytic Pathways During Lung Injuries

Oral administration of a dual ETA/ETB receptor antagonist promotes neuroprotection in a rodent model of glaucoma

Hybrid Compound SA-2 is Neuroprotective in Animal Models of Retinal Ganglion Cell Death

Bcl-2, Bcl-xL, and p-AKT are involved in neuroprotective effects of transcription factor Brn3b in an ocular hypertension rat model of glaucoma

Nanoencapsulated hybrid compound SA-2 with long-lasting intraocular pressure-lowering activity in rodent eyes

Upregulation of the endothelin A (ET A ) receptor and its association with neurodegeneration in a rodent model of glaucoma

Neuroprotective effects of curcumin on endothelin-1 mediated cell death in hippocampal neurons

Design and synthesis of novel hybrid sydnonimine and prodrug useful for glaucomatous optic neuropathy

Sigma-1 receptor stimulation attenuates calcium influx through activated L-type Voltage Gated Calcium Channels in purified retinal ganglion cells

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