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Obesity and cancer, a case for insulin signaling

Cell death & disease, 2015-12, Vol.6 (12), p.e2037-e2037

2015

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Nuclear PTEN Controls DNA Repair and Sensitivity to Genotoxic Stress

Science (American Association for the Advancement of Science), 2013-07, Vol.341 (6144), p.395-399

2013

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The acetyltransferase Tip60 contributes to mammary tumorigenesis by modulating DNA repair

Cell death and differentiation, 2016-07, Vol.23 (7), p.1198-1208

2016

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Characterization of nuclear PTEN and its post translational modifications

Methods (San Diego, Calif.), 2015-05, Vol.77-78, p.104-111

2015

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PTEN, here, there, everywhere

Cell death and differentiation, 2013-12, Vol.20 (12), p.1595-1596

2013

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Regulation of PTEN Transcription by p53

Molecular cell, 2001-08, Vol.8 (2), p.317-325

2001

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Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation

Biochemical journal, 1994-11, Vol.303 ( Pt 3) (3), p.701-704

1994

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mTORC1 and CK2 coordinate ternary and eIF4F complex assembly

Nature communications, 2016-04, Vol.7 (1), p.11127-11127, Article 11127

2016

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Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells

Current biology, 1996-12, Vol.6 (12), p.1664-1669

1996

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Effect of metformin vs placebo on and metabolic factors in NCIC CTG MA.32

JNCI : Journal of the National Cancer Institute, 2015-03, Vol.107 (3), p.djv006-djv006

2015

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Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

Nature genetics, 2001-12, Vol.29 (4), p.396-403

2001

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Abstract P6-02-03: Leptin receptor (OB-R) in breast carcinoma tissue: Ubiquitous expression and correlation with leptin-mediated signaling, but not with systemic markers of obesity

Cancer research (Chicago, Ill.), 2017-02, Vol.77 (4_Supplement), p.P6-P6-02-03

2017

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Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN

Cell, 1998-10, Vol.95 (1), p.29-39

1998

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Abstract OT1-12-01: Exploration of factors associated with imminent risk of late recurrence in hormone receptor positive breast cancer

Cancer research (Chicago, Ill.), 2019-02, Vol.79 (4_Supplement), p.OT1-12-01-OT1-12-01

2019

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Abstract P1-02-03: Circulating inflammatory markers, growth factors, and tumor associated antigens in women with early stage breast cancer receiving neoadjuvant metformin

Cancer research (Chicago, Ill.), 2017-02, Vol.77 (4_Supplement), p.P1-P1-02-03

2017

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Abstract P1-16-03: Phase II randomized clinical trial (RCT) of metformin (MET) vs placebo (PLAC) in combination with chemotherapy (CXT) in refractory locally advanced (LABC) or metastatic breast cancer (MBC)

Cancer research (Chicago, Ill.), 2019-02, Vol.79 (4_Supplement), p.P1-P1-16-03

2019

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High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice

Cancer research (Chicago, Ill.), 2000-07, Vol.60 (13), p.3605-3611

2000

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Early Onset of Neoplasia in the Prostate and Skin of Mice with Tissue-Specific Deletion of PTEN

Proceedings of the National Academy of Sciences - PNAS, 2004-02, Vol.101 (6), p.1725-1730

2004

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Restricted Accumulation of Phosphatidylinositol 3-Kinase Products in a Plasmalemmal Subdomain during Fcγ Receptor-Mediated Phagocytosis

The Journal of cell biology, 2001-06, Vol.153 (7), p.1369-1380

2001

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Abstract P2-09-14: Association between BMI and residual estradiol levels in post-menopausal women using adjuvant letrozole: Results of a prospective study

Cancer research (Chicago, Ill.), 2017-02, Vol.77 (4_Supplement), p.P2-P2-09-14

2017

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High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

Current biology, 1998-10, Vol.8 (21), p.1169-1178

1998

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P3.03-008 Organoid Cultures of Lung Squamous Cell Carcinoma for Drug Screening

Journal of thoracic oncology, 2017-11, Vol.12 (11), p.S2276-S2276

2017

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Abstract P5-12-02: Effect of 5 vs 2.5 mg/day letrozole on residual estrogen levels in post-menopausal women with high BMI - A prospective crossover study

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P5-P5-12-02

2016

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Abstract P2-02-12: Association of inflammatory and tumor markers with circulating tumor cells in metastatic breast cancer

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P2-P2-02-12

2016

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Abstract P2-02-09: Obesity associated factors are inversely associated with circulating tumor cells in metastatic breast cancer

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P2-P2-02-09

2016

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Obesity and cancer, a case for insulin signaling

Nuclear PTEN Controls DNA Repair and Sensitivity to Genotoxic Stress

The acetyltransferase Tip60 contributes to mammary tumorigenesis by modulating DNA repair

Characterization of nuclear PTEN and its post translational modifications

PTEN, here, there, everywhere

Regulation of PTEN Transcription by p53

Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation

mTORC1 and CK2 coordinate ternary and eIF4F complex assembly

Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells

Effect of metformin vs placebo on and metabolic factors in NCIC CTG MA.32

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

Abstract P6-02-03: Leptin receptor (OB-R) in breast carcinoma tissue: Ubiquitous expression and correlation with leptin-mediated signaling, but not with systemic markers of obesity

Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN

Abstract OT1-12-01: Exploration of factors associated with imminent risk of late recurrence in hormone receptor positive breast cancer

Abstract P1-02-03: Circulating inflammatory markers, growth factors, and tumor associated antigens in women with early stage breast cancer receiving neoadjuvant metformin

Abstract P1-16-03: Phase II randomized clinical trial (RCT) of metformin (MET) vs placebo (PLAC) in combination with chemotherapy (CXT) in refractory locally advanced (LABC) or metastatic breast cancer (MBC)

High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice

Early Onset of Neoplasia in the Prostate and Skin of Mice with Tissue-Specific Deletion of PTEN

Restricted Accumulation of Phosphatidylinositol 3-Kinase Products in a Plasmalemmal Subdomain during Fcγ Receptor-Mediated Phagocytosis

Abstract P2-09-14: Association between BMI and residual estradiol levels in post-menopausal women using adjuvant letrozole: Results of a prospective study

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

P3.03-008 Organoid Cultures of Lung Squamous Cell Carcinoma for Drug Screening

Abstract P5-12-02: Effect of 5 vs 2.5 mg/day letrozole on residual estrogen levels in post-menopausal women with high BMI - A prospective crossover study

Abstract P2-02-12: Association of inflammatory and tumor markers with circulating tumor cells in metastatic breast cancer

Abstract P2-02-09: Obesity associated factors are inversely associated with circulating tumor cells in metastatic breast cancer

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